IT1170232B - Composizioni terapeutiche ad attivita' antivirale - Google Patents
Composizioni terapeutiche ad attivita' antiviraleInfo
- Publication number
- IT1170232B IT1170232B IT23545/83A IT2354583A IT1170232B IT 1170232 B IT1170232 B IT 1170232B IT 23545/83 A IT23545/83 A IT 23545/83A IT 2354583 A IT2354583 A IT 2354583A IT 1170232 B IT1170232 B IT 1170232B
- Authority
- IT
- Italy
- Prior art keywords
- bvdu
- acyclovir
- compositions
- therapeutic compositions
- potentiated
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- ODZBBRURCPAEIQ-DJLDLDEBSA-N Brivudine Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(C=CBr)=C1 ODZBBRURCPAEIQ-DJLDLDEBSA-N 0.000 abstract 3
- MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 abstract 3
- 229960004150 aciclovir Drugs 0.000 abstract 3
- 239000007858 starting material Substances 0.000 abstract 1
- 238000011287 therapeutic dose Methods 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT23545/83A IT1170232B (it) | 1983-10-31 | 1983-10-31 | Composizioni terapeutiche ad attivita' antivirale |
| AT84113011T ATE40854T1 (de) | 1983-10-31 | 1984-10-29 | Therapeutische zusammensetzungen mit antiviraler wirksamkeit. |
| DE8484113011T DE3476784D1 (en) | 1983-10-31 | 1984-10-29 | Therapeutic compositions endowed with antiviral activity |
| EP84113011A EP0143987B1 (en) | 1983-10-31 | 1984-10-29 | Therapeutic compositions endowed with antiviral activity |
| JP59230031A JPS60120814A (ja) | 1983-10-31 | 1984-10-31 | 抗ウイルス活性の治療用組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT23545/83A IT1170232B (it) | 1983-10-31 | 1983-10-31 | Composizioni terapeutiche ad attivita' antivirale |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8323545A0 IT8323545A0 (it) | 1983-10-31 |
| IT1170232B true IT1170232B (it) | 1987-06-03 |
Family
ID=11208018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT23545/83A IT1170232B (it) | 1983-10-31 | 1983-10-31 | Composizioni terapeutiche ad attivita' antivirale |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0143987B1 (it) |
| JP (1) | JPS60120814A (it) |
| AT (1) | ATE40854T1 (it) |
| DE (1) | DE3476784D1 (it) |
| IT (1) | IT1170232B (it) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8700366A (nl) * | 1987-02-13 | 1988-09-01 | Stichting Rega V Z W | Combinatie van fu met bvdu als middel tegen adenocarcinoom. |
| GB8829571D0 (en) * | 1988-12-19 | 1989-02-08 | Wellcome Found | Antiviral compounds |
| DE69311135T2 (de) * | 1992-12-03 | 1997-09-25 | Merrell Pharmaceuticals Inc., Cincinnati, Ohio | Zubereitungen, die acyclovir-ähnliche verbindungen und 2'-vinylsubstituierte nukleosidanaloge enthalten, zur behandlung viraler infektionen |
| AU2768295A (en) * | 1994-07-11 | 1996-02-09 | Hoechst Marion Roussel, Inc. | Method of treating a neoplastic disease state by conjunctive therapy with 2'-fluoromethylidene derivatives and radiation or chemotherapy |
| US5789589A (en) * | 1996-04-22 | 1998-08-04 | Drug Innovation & Design, Inc. | Guanine analog phosphates |
| US6180790B1 (en) | 1997-05-15 | 2001-01-30 | Drug Innovation And Design, Inc. | Methods of preparing acyclovir prodrugs |
| DE69807464T2 (de) * | 1997-05-15 | 2003-05-15 | Drug Innovation & Design, Inc. | Diester-derivate von acyclovir |
| ITMI20010009A1 (it) * | 2001-01-03 | 2002-07-03 | Menarini Ricerche Spa | Composizioni farmaceutica contenente brivudina per la singola somministrazione giornaliera |
| DE10108851A1 (de) | 2001-02-23 | 2002-09-12 | Resprotect Gmbh | Verwendung von 5'-substituierten Nukleosiden und/oder deren Prodrugs zur resistenzfreien Therapie von Infektionskrankheiten |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4199574A (en) * | 1974-09-02 | 1980-04-22 | Burroughs Wellcome Co. | Methods and compositions for treating viral infections and guanine acyclic nucleosides |
| DE3275061D1 (en) * | 1982-02-12 | 1987-02-19 | Ens Bio Logicals Inc | Anti-viral compositions |
-
1983
- 1983-10-31 IT IT23545/83A patent/IT1170232B/it active
-
1984
- 1984-10-29 EP EP84113011A patent/EP0143987B1/en not_active Expired
- 1984-10-29 DE DE8484113011T patent/DE3476784D1/de not_active Expired
- 1984-10-29 AT AT84113011T patent/ATE40854T1/de not_active IP Right Cessation
- 1984-10-31 JP JP59230031A patent/JPS60120814A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0143987A1 (en) | 1985-06-12 |
| JPS60120814A (ja) | 1985-06-28 |
| ATE40854T1 (de) | 1989-03-15 |
| IT8323545A0 (it) | 1983-10-31 |
| EP0143987B1 (en) | 1989-02-22 |
| DE3476784D1 (en) | 1989-03-30 |
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