ATE218875T1 - Eisen-dextran formulierungen - Google Patents
Eisen-dextran formulierungenInfo
- Publication number
- ATE218875T1 ATE218875T1 AT96930686T AT96930686T ATE218875T1 AT E218875 T1 ATE218875 T1 AT E218875T1 AT 96930686 T AT96930686 T AT 96930686T AT 96930686 T AT96930686 T AT 96930686T AT E218875 T1 ATE218875 T1 AT E218875T1
- Authority
- AT
- Austria
- Prior art keywords
- iron dextran
- dextran formulations
- formulations
- daltons
- molecular weight
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- MVZXTUSAYBWAAM-UHFFFAOYSA-N iron;sulfuric acid Chemical compound [Fe].OS(O)(=O)=O MVZXTUSAYBWAAM-UHFFFAOYSA-N 0.000 title 1
- 229920002307 Dextran Polymers 0.000 abstract 1
- 206010022971 Iron Deficiencies Diseases 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/536,984 US5624668A (en) | 1995-09-29 | 1995-09-29 | Iron dextran formulations |
| PCT/US1996/014153 WO1997011711A1 (en) | 1995-09-29 | 1996-08-29 | Iron dextran formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE218875T1 true ATE218875T1 (de) | 2002-06-15 |
Family
ID=24140716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96930686T ATE218875T1 (de) | 1995-09-29 | 1996-08-29 | Eisen-dextran formulierungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5624668A (de) |
| EP (1) | EP0855913B1 (de) |
| JP (1) | JP3471363B2 (de) |
| AT (1) | ATE218875T1 (de) |
| AU (1) | AU702691B2 (de) |
| CA (1) | CA2184551C (de) |
| DE (1) | DE69621813T2 (de) |
| DK (1) | DK0855913T3 (de) |
| ES (1) | ES2179207T3 (de) |
| PT (1) | PT855913E (de) |
| WO (1) | WO1997011711A1 (de) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6306384B1 (en) * | 1996-10-01 | 2001-10-23 | E-L Management Corp. | Skin battery cosmetic composition |
| DK172860B1 (da) * | 1998-03-25 | 1999-08-16 | Pharmacosmos Holding As | Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman |
| US6610206B1 (en) | 1998-10-20 | 2003-08-26 | Advanced Renal Technologies | Buffered compositions for dialysis |
| US7670491B2 (en) * | 1998-10-20 | 2010-03-02 | Advanced Renal Technologies | Buffered compositions for dialysis |
| DK173138B1 (da) | 1998-11-20 | 2000-02-07 | Pharmacosmos Holding As | Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma |
| WO2001021233A1 (en) * | 1999-09-22 | 2001-03-29 | Advanced Renal Technologies | High citrate dialysate and uses thereof |
| EP1330226A4 (de) * | 2000-11-02 | 2005-11-23 | Chromaceutical Advanced Tech | Verfahren zur herstellung eines gereinigten hämatin-eisen-saccharid-komplexes und hergestelltes produkt |
| US6929954B2 (en) * | 2000-11-02 | 2005-08-16 | Chromaceutical Advanced Technologies, Inc. | Method for producing purified hematinic iron-saccharidic complex and product produced |
| EP1719496A3 (de) * | 2000-11-02 | 2007-05-16 | Chromaceutical Advanced Technologies, Inc. | Verfahren zur Herstellung eines gereinigten Hämatin-Eisen-Saccharid-Komplexes und hergestelltes Produkt |
| US6825032B2 (en) * | 2001-05-14 | 2004-11-30 | Sigma-Aldrich Co. | High capacity assay platforms |
| EP1540338B1 (de) * | 2002-08-26 | 2008-10-08 | Vifor (International) Ag | Bioäquivalenztest für eisenhaltige formulierungen |
| US7169359B2 (en) * | 2002-08-26 | 2007-01-30 | Luitpold Pharmaceuticals, Inc. | Bioequivalence test for iron-containing formulations |
| DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| US7390472B1 (en) * | 2002-10-29 | 2008-06-24 | Nei Corp. | Method of making nanostructured lithium iron phosphate—based powders with an olivine type structure |
| US20040161852A1 (en) * | 2003-02-14 | 2004-08-19 | Anderson Christopher G. | Method of assaying an Fe-Sugar complex |
| US20060116349A1 (en) * | 2003-03-14 | 2006-06-01 | Luitpold Pharmaceuticals, Inc. | Methods and compositions for administration of iron for the treatment of restless leg syndrome |
| US7964568B2 (en) * | 2003-05-30 | 2011-06-21 | Chromaceutical Advanced Technologies, Inc. | Synthesis of high molecular weight iron-saccharidic complexes |
| WO2006017179A1 (en) | 2004-07-09 | 2006-02-16 | Robert Sabin | Compositions and methods of use for treatment of mammalian diseases |
| US7449196B2 (en) * | 2004-07-09 | 2008-11-11 | Robert Sabin | Anti tumor compositions and methods of use |
| AU2016205002C1 (en) * | 2006-01-06 | 2020-09-24 | Vifor (International) Ag | Methods and compositions for administration of iron |
| PT1973549T (pt) | 2006-01-06 | 2016-10-25 | Luitpold Pharm Inc | Métodos e composições para administração de ferro |
| AU2013206429B2 (en) * | 2006-01-06 | 2016-04-28 | Vifor (International) Ag | Methods and compositions for administration of iron |
| US20080081051A1 (en) * | 2006-09-28 | 2008-04-03 | Robert Sabin | Method of manufacturing anti-tumor and anti-viral compositions |
| US20080132465A1 (en) * | 2006-12-05 | 2008-06-05 | Vincent Windisch | Apparatus and method for isolating iron components from serum |
| EP2123270B2 (de) * | 2006-12-12 | 2016-06-15 | Advanced Renal Technologies, Inc. | Mittel zur verbesserung des eisenstoffwechsels |
| TWI468167B (zh) | 2007-11-16 | 2015-01-11 | 威佛（國際）股份有限公司 | 藥學組成物 |
| EP2411053B1 (de) | 2009-03-25 | 2016-11-30 | Pharmacosmos Holding A/s | Stabile eisen-oligosaccharid-verbindung |
| US8058076B2 (en) * | 2009-03-31 | 2011-11-15 | Astron Research Limited | In-vitro method for testing bioequivalence of iron-sucrose formulation |
| PT104879B (pt) * | 2009-12-10 | 2012-10-17 | Univ Do Minho | Hidrogel de dextrino para aplicações biomédicas |
| CN103044571A (zh) * | 2011-10-13 | 2013-04-17 | 天津中敖生物科技有限公司 | 右旋糖酐铁原料药及其制备方法 |
| JP6189309B2 (ja) | 2011-10-13 | 2017-08-30 | ヴィダシム・インコーポレーテッド | 鉄−繊維組成物、その調製および使用 |
| AU2014226059B9 (en) * | 2013-03-08 | 2018-05-10 | Alebund Pharmaceuticals (Hong Kong) Limited | Metal ion-functional fiber component complex compositions, preparation and uses thereof |
| US9370202B2 (en) * | 2013-03-15 | 2016-06-21 | LG Bionano, LLC | Encapsulated metal ion nanoclusters |
| WO2018198135A1 (en) * | 2017-04-26 | 2018-11-01 | Mylan Laboratories Ltd. | Improved process for the preparation of iron complex |
| AU2018328052C1 (en) | 2017-09-11 | 2025-12-18 | Pharmacosmos Holding A/S | Iron complex compounds for therapeutic use |
| AU2018381338B2 (en) * | 2017-12-07 | 2022-12-08 | Commonwealth Scientific And Industrial Research Organisation | Sugar reduced products and method of producing thereof |
| CN119488480A (zh) | 2019-02-28 | 2025-02-21 | 雷尼布斯治疗公司 | 新型铁组合物及其制造和使用方法 |
| CN113567370A (zh) * | 2021-07-23 | 2021-10-29 | 广西南宁市桃源兽药厂 | 一种用于检测右旋糖酐铁注射液中糖酐含量的方法 |
| CN116712455B (zh) * | 2023-06-30 | 2024-04-05 | 重庆汉佩生物科技有限公司 | 一种氟苯尼考与葡庚糖酐铁的组合物 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE24642E (en) * | 1959-04-28 | Therapeutic preparations of iron | ||
| US2820740A (en) * | 1953-02-27 | 1958-01-21 | Benger Lab Ltd | Therapeutic preparations of iron |
| US2885393A (en) * | 1956-02-24 | 1959-05-05 | R K Laros Company | Dextran-iron complex and process for making same |
| US3697502A (en) * | 1969-11-03 | 1972-10-10 | Christensen Henry M | Method of making iron dextran-preparations |
| US3686397A (en) * | 1970-05-18 | 1972-08-22 | Mueller Arthur | Parenteral iron preparations |
| US3908004A (en) * | 1970-05-20 | 1975-09-23 | C L Basingstoke Limited | Process for making injectable iron compositions for treating iron-deficiency anemia |
| JPS5913521B2 (ja) * | 1975-06-19 | 1984-03-30 | メイトウサンギヨウ カブシキガイシヤ | 磁性酸化鉄・デキストラン複合体の製造法 |
| US4180567A (en) * | 1977-09-02 | 1979-12-25 | Pharmachem Corporation | Iron preparations and methods of making and administering the same |
| DE3026868C2 (de) * | 1980-07-16 | 1986-03-13 | Laboratorien Hausmann AG, St. Gallen | Verfahren zur Herstellung von Eisen(III)hydroxid-Dextran-Komplexen und sie enthaltende pharmazeutische sterile wäßrige Lösung |
| US4454773A (en) * | 1981-11-06 | 1984-06-19 | Texaco Inc. | Time interval automatic well multi-phase fluid sampler |
| US4452773A (en) * | 1982-04-05 | 1984-06-05 | Canadian Patents And Development Limited | Magnetic iron-dextran microspheres |
| JPS58199018A (ja) * | 1982-05-18 | 1983-11-19 | Nippon Denso Co Ltd | 電気的加熱手段を有する排気ガス微粒子浄化装置 |
| US4659697A (en) * | 1983-05-20 | 1987-04-21 | Kentaro Tanaka | Antianaemic composition and a process for producing the same |
| US4788281A (en) * | 1984-01-04 | 1988-11-29 | Tosoni Anthony L | Dextran hexonic acid derivative, ferric hydroxide complex and method manufacture thereof |
| DE3422249A1 (de) * | 1984-06-15 | 1985-12-19 | Pfeifer & Langen, 5000 Köln | Wasserloesliches eisendextran und verfahren zu seiner herstellung |
| US5248492A (en) * | 1986-07-03 | 1993-09-28 | Advanced Magnetics, Inc. | Low molecular weight carbohydrates as additives to stabilize metal oxide compositions |
| US5102652A (en) * | 1986-07-03 | 1992-04-07 | Advanced Magnetics Inc. | Low molecular weight carbohydrates as additives to stabilize metal oxide compositions |
| US5336506A (en) * | 1986-07-03 | 1994-08-09 | Advanced Magnetics Inc. | Targeting of therapeutic agents using polysaccharides |
| US5118513A (en) * | 1987-07-02 | 1992-06-02 | The Procter & Gamble Company | Method for enhancing bioavailability of iron-calcium mineral supplements |
| US5354350A (en) * | 1993-12-14 | 1994-10-11 | The Vigoro Corporation | Citrate soluble slow release iron humate |
-
1995
- 1995-09-29 US US08/536,984 patent/US5624668A/en not_active Expired - Lifetime
-
1996
- 1996-08-29 EP EP96930686A patent/EP0855913B1/de not_active Expired - Lifetime
- 1996-08-29 AU AU69647/96A patent/AU702691B2/en not_active Ceased
- 1996-08-29 WO PCT/US1996/014153 patent/WO1997011711A1/en not_active Ceased
- 1996-08-29 ES ES96930686T patent/ES2179207T3/es not_active Expired - Lifetime
- 1996-08-29 DE DE69621813T patent/DE69621813T2/de not_active Expired - Lifetime
- 1996-08-29 DK DK96930686T patent/DK0855913T3/da active
- 1996-08-29 PT PT96930686T patent/PT855913E/pt unknown
- 1996-08-29 JP JP51343997A patent/JP3471363B2/ja not_active Expired - Lifetime
- 1996-08-29 AT AT96930686T patent/ATE218875T1/de active
- 1996-08-30 CA CA002184551A patent/CA2184551C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT855913E (pt) | 2002-11-29 |
| US5624668A (en) | 1997-04-29 |
| EP0855913B1 (de) | 2002-06-12 |
| AU6964796A (en) | 1997-04-17 |
| DK0855913T3 (da) | 2002-10-07 |
| EP0855913A1 (de) | 1998-08-05 |
| JPH11512706A (ja) | 1999-11-02 |
| ES2179207T3 (es) | 2003-01-16 |
| DE69621813D1 (de) | 2002-07-18 |
| CA2184551A1 (en) | 1997-03-30 |
| CA2184551C (en) | 2001-11-27 |
| WO1997011711A1 (en) | 1997-04-03 |
| DE69621813T2 (de) | 2003-01-23 |
| AU702691B2 (en) | 1999-03-04 |
| EP0855913A4 (de) | 1999-01-20 |
| JP3471363B2 (ja) | 2003-12-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEIH | Change in the person of patent owner |