ATE217610T1 - Methansulfonatsalz eines arylpiperazinderivat von tryptamin und seine solvate zur pharmazeutische verwendung - Google Patents
Methansulfonatsalz eines arylpiperazinderivat von tryptamin und seine solvate zur pharmazeutische verwendungInfo
- Publication number
- ATE217610T1 ATE217610T1 AT97928341T AT97928341T ATE217610T1 AT E217610 T1 ATE217610 T1 AT E217610T1 AT 97928341 T AT97928341 T AT 97928341T AT 97928341 T AT97928341 T AT 97928341T AT E217610 T1 ATE217610 T1 AT E217610T1
- Authority
- AT
- Austria
- Prior art keywords
- solvates
- pct
- tryptamine
- salt
- pharmaceutical use
- Prior art date
Links
- 239000012453 solvate Substances 0.000 title abstract 2
- YKGMKSIHIVVYKY-UHFFFAOYSA-N dabrafenib mesylate Chemical compound CS(O)(=O)=O.S1C(C(C)(C)C)=NC(C=2C(=C(NS(=O)(=O)C=3C(=CC=CC=3F)F)C=CC=2)F)=C1C1=CC=NC(N)=N1 YKGMKSIHIVVYKY-UHFFFAOYSA-N 0.000 title 1
- APJYDQYYACXCRM-UHFFFAOYSA-N tryptamine Chemical class C1=CC=C2C(CCN)=CNC2=C1 APJYDQYYACXCRM-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical class CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 1
- SOHCKWZVTCTQBG-UHFFFAOYSA-N donitriptan Chemical compound C1=C2C(CCN)=CNC2=CC=C1OCC(=O)N(CC1)CCN1C1=CC=C(C#N)C=C1 SOHCKWZVTCTQBG-UHFFFAOYSA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002455 vasospastic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9607491A FR2749846B1 (fr) | 1996-06-17 | 1996-06-17 | Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique |
| PCT/FR1997/001053 WO1997048680A1 (fr) | 1996-06-17 | 1997-06-12 | Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE217610T1 true ATE217610T1 (de) | 2002-06-15 |
Family
ID=9493116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97928341T ATE217610T1 (de) | 1996-06-17 | 1997-06-12 | Methansulfonatsalz eines arylpiperazinderivat von tryptamin und seine solvate zur pharmazeutische verwendung |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6110917A (de) |
| EP (1) | EP0923549B1 (de) |
| JP (1) | JP2000512307A (de) |
| CN (1) | CN1086385C (de) |
| AT (1) | ATE217610T1 (de) |
| AU (1) | AU714471B2 (de) |
| BR (1) | BR9709807A (de) |
| CA (1) | CA2258919A1 (de) |
| DE (1) | DE69712626T2 (de) |
| DK (1) | DK0923549T3 (de) |
| ES (1) | ES2175424T3 (de) |
| FR (1) | FR2749846B1 (de) |
| NZ (1) | NZ333506A (de) |
| PT (1) | PT923549E (de) |
| WO (1) | WO1997048680A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001015677A2 (en) * | 1999-08-31 | 2001-03-08 | Alcon Laboratories, Inc. | Use of 5-ht1b/1d agonists to treat otic pain |
| AR043880A1 (es) * | 2003-04-22 | 2005-08-17 | Solvay Pharm Gmbh | Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas |
| NZ719671A (en) * | 2013-12-02 | 2017-03-31 | Suven Life Sciences Ltd | Process for large scale production of 1-[(2-bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1h-indole dimesylate monohydrate |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2162522B (en) * | 1984-08-01 | 1988-02-24 | Glaxo Group Ltd | An indole derivative |
| GB8600397D0 (en) * | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
| GB9026998D0 (en) * | 1990-12-12 | 1991-01-30 | Glaxo Group Ltd | Medicaments |
| FR2712591B1 (fr) * | 1993-11-19 | 1996-02-09 | Pf Medicament | Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique. |
-
1996
- 1996-06-17 FR FR9607491A patent/FR2749846B1/fr not_active Expired - Fee Related
-
1997
- 1997-06-12 CA CA002258919A patent/CA2258919A1/fr not_active Abandoned
- 1997-06-12 PT PT97928341T patent/PT923549E/pt unknown
- 1997-06-12 ES ES97928341T patent/ES2175424T3/es not_active Expired - Lifetime
- 1997-06-12 AU AU32670/97A patent/AU714471B2/en not_active Ceased
- 1997-06-12 AT AT97928341T patent/ATE217610T1/de not_active IP Right Cessation
- 1997-06-12 WO PCT/FR1997/001053 patent/WO1997048680A1/fr not_active Ceased
- 1997-06-12 BR BR9709807A patent/BR9709807A/pt not_active Application Discontinuation
- 1997-06-12 JP JP10502420A patent/JP2000512307A/ja not_active Ceased
- 1997-06-12 CN CN97196451A patent/CN1086385C/zh not_active Expired - Fee Related
- 1997-06-12 DE DE69712626T patent/DE69712626T2/de not_active Expired - Fee Related
- 1997-06-12 EP EP97928341A patent/EP0923549B1/de not_active Expired - Lifetime
- 1997-06-12 NZ NZ333506A patent/NZ333506A/xx unknown
- 1997-06-12 US US09/202,539 patent/US6110917A/en not_active Expired - Fee Related
- 1997-06-12 DK DK97928341T patent/DK0923549T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| DE69712626D1 (de) | 2002-06-20 |
| DE69712626T2 (de) | 2002-11-28 |
| FR2749846B1 (fr) | 1998-09-11 |
| WO1997048680A1 (fr) | 1997-12-24 |
| EP0923549A1 (de) | 1999-06-23 |
| US6110917A (en) | 2000-08-29 |
| FR2749846A1 (fr) | 1997-12-19 |
| EP0923549B1 (de) | 2002-05-15 |
| NZ333506A (en) | 2000-01-28 |
| PT923549E (pt) | 2002-10-31 |
| AU3267097A (en) | 1998-01-07 |
| DK0923549T3 (da) | 2002-09-09 |
| JP2000512307A (ja) | 2000-09-19 |
| CN1086385C (zh) | 2002-06-19 |
| AU714471B2 (en) | 2000-01-06 |
| ES2175424T3 (es) | 2002-11-16 |
| BR9709807A (pt) | 1999-08-10 |
| CA2258919A1 (fr) | 1997-12-24 |
| CN1225630A (zh) | 1999-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |