ATE215968T1 - Verfahren zur reinigung von thrombomodulin - Google Patents
Verfahren zur reinigung von thrombomodulinInfo
- Publication number
- ATE215968T1 ATE215968T1 AT96117071T AT96117071T ATE215968T1 AT E215968 T1 ATE215968 T1 AT E215968T1 AT 96117071 T AT96117071 T AT 96117071T AT 96117071 T AT96117071 T AT 96117071T AT E215968 T1 ATE215968 T1 AT E215968T1
- Authority
- AT
- Austria
- Prior art keywords
- thrombomodulin
- purified
- purifying
- purifying thrombomodulin
- content
- Prior art date
Links
- 102000012607 Thrombomodulin Human genes 0.000 title abstract 4
- 108010079274 Thrombomodulin Proteins 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 238000000746 purification Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/7455—Thrombomodulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP30068295A JP3745805B2 (ja) | 1995-10-24 | 1995-10-24 | トロンボモジュリンの精製方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE215968T1 true ATE215968T1 (de) | 2002-04-15 |
Family
ID=17887810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96117071T ATE215968T1 (de) | 1995-10-24 | 1996-10-24 | Verfahren zur reinigung von thrombomodulin |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5753123A (de) |
| EP (1) | EP0770626B1 (de) |
| JP (1) | JP3745805B2 (de) |
| CN (1) | CN1151406A (de) |
| AT (1) | ATE215968T1 (de) |
| DE (1) | DE69620539T2 (de) |
| TW (1) | TW408129B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1781778A4 (de) * | 2004-06-16 | 2007-09-12 | Ciphergen Biosystems Inc | Multichemiefraktionierung |
| EP1831242B1 (de) * | 2004-12-23 | 2012-09-26 | Novo Nordisk Health Care AG | Reduktion des gehaltes an kontaminierenden proteinen in zusammensetzungen, die vitamin k-abhängige proteine von interesse umfassen |
| MX2009003384A (es) | 2006-10-06 | 2009-04-08 | Asahi Kasei Pharma Corp | Agente terapeutico y/o de mejoramiento para la coagulacion intravascular diseminada. |
| CA2681294C (en) | 2007-03-23 | 2014-05-06 | Asahi Kasei Pharma Corporation | Method for producing high-purity soluble thrombomodulin |
| NZ602852A (en) * | 2010-04-30 | 2014-03-28 | Asahi Kasei Pharma Corp | Highly-purified soluble thrombomodulin and method for producing same |
| PT2781221T (pt) | 2011-11-15 | 2020-06-01 | Asahi Kasei Pharma Corp | Medicamento para tratamento e/ou melhoria de sepsia |
| DK2857037T3 (da) | 2012-05-31 | 2019-07-22 | Univ Kinki | Middel til forebyggelse og/eller behandling af perifere neuropatiske smerter forårsaget af anticancerlægemiddel |
| CN107987157A (zh) * | 2017-12-19 | 2018-05-04 | 江苏艾迪药业有限公司 | 一种可工业化生产的人来源血凝调节蛋白的制备方法 |
| CA3112679A1 (en) | 2018-09-28 | 2020-04-02 | Asahi Kasei Pharma Corporation | Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent |
| BR112021007460A2 (pt) | 2018-10-22 | 2021-11-03 | Asahi Kasei Pharma Corp | Medicamento para tratamento terapêutico e/ou melhora de um paciente com sepse |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USH1148H (en) * | 1987-04-17 | 1993-03-02 | Method of separating activated human protein C | |
| US5202421A (en) * | 1988-12-27 | 1993-04-13 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant substance obtained from urine and process for the preparation thereof |
| FR2658517B2 (fr) * | 1989-04-12 | 1992-06-19 | Fondation Nale Transfusion San | Preparation de la proteine c activee et solution de proteine c activee ainsi obtenue. |
| GB9007657D0 (en) * | 1990-04-04 | 1990-05-30 | Connaught Lab | Purification of a pertussis outer membrane protein(omp69) |
| US5378816A (en) * | 1992-12-16 | 1995-01-03 | Berlex Laboratories, Inc. | Methods for high purity chromatographic separation of proteins having EGF-like binding domains |
-
1995
- 1995-10-24 JP JP30068295A patent/JP3745805B2/ja not_active Expired - Fee Related
-
1996
- 1996-10-23 US US08/735,950 patent/US5753123A/en not_active Expired - Fee Related
- 1996-10-23 CN CN96112462A patent/CN1151406A/zh active Pending
- 1996-10-24 EP EP96117071A patent/EP0770626B1/de not_active Expired - Lifetime
- 1996-10-24 TW TW085113059A patent/TW408129B/zh not_active IP Right Cessation
- 1996-10-24 AT AT96117071T patent/ATE215968T1/de not_active IP Right Cessation
- 1996-10-24 DE DE69620539T patent/DE69620539T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69620539D1 (de) | 2002-05-16 |
| EP0770626B1 (de) | 2002-04-10 |
| JP3745805B2 (ja) | 2006-02-15 |
| EP0770626A2 (de) | 1997-05-02 |
| CN1151406A (zh) | 1997-06-11 |
| US5753123A (en) | 1998-05-19 |
| EP0770626A3 (de) | 1998-04-08 |
| JPH09110900A (ja) | 1997-04-28 |
| TW408129B (en) | 2000-10-11 |
| DE69620539T2 (de) | 2002-08-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |