ATE215068T1 - N-acylaminoalkylhydrazinecarboximidamide - Google Patents

N-acylaminoalkylhydrazinecarboximidamide

Info

Publication number
ATE215068T1
ATE215068T1 AT96945113T AT96945113T ATE215068T1 AT E215068 T1 ATE215068 T1 AT E215068T1 AT 96945113 T AT96945113 T AT 96945113T AT 96945113 T AT96945113 T AT 96945113T AT E215068 T1 ATE215068 T1 AT E215068T1
Authority
AT
Austria
Prior art keywords
carbon atoms
composition
group containing
inhibiting
protein
Prior art date
Application number
AT96945113T
Other languages
English (en)
Inventor
Peter C Ulrich
Dilip R Wagle
Original Assignee
Alteon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/771,959 external-priority patent/US5877217A/en
Application filed by Alteon Inc filed Critical Alteon Inc
Application granted granted Critical
Publication of ATE215068T1 publication Critical patent/ATE215068T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT96945113T 1995-12-26 1996-12-26 N-acylaminoalkylhydrazinecarboximidamide ATE215068T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US922095P 1995-12-26 1995-12-26
US61840796A 1996-03-19 1996-03-19
US08/771,959 US5877217A (en) 1995-12-26 1996-12-23 N-acylaminoalkyl-hydrazinecarboximidamides
PCT/US1996/020810 WO1997023447A1 (en) 1995-12-26 1996-12-26 N-acylaminoalkylhydrazinecarboximidamides

Publications (1)

Publication Number Publication Date
ATE215068T1 true ATE215068T1 (de) 2002-04-15

Family

ID=27358809

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96945113T ATE215068T1 (de) 1995-12-26 1996-12-26 N-acylaminoalkylhydrazinecarboximidamide

Country Status (15)

Country Link
EP (1) EP0888293B1 (de)
JP (1) JP2000502684A (de)
CN (1) CN1209117A (de)
AT (1) ATE215068T1 (de)
AU (1) AU720796B2 (de)
BR (1) BR9612304A (de)
CA (1) CA2241746A1 (de)
DE (1) DE69620253T2 (de)
DK (1) DK0888293T3 (de)
ES (1) ES2174132T3 (de)
NO (1) NO982976L (de)
NZ (1) NZ326238A (de)
PT (1) PT888293E (de)
TW (1) TW502012B (de)
WO (1) WO1997023447A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
MX2008014024A (es) 2006-05-04 2008-11-14 Boehringer Ingelheim Int Formas poliformas.
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
EP1852108A1 (de) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG Zusammensetzungen von DPP-IV-Inhibitoren
PE20140960A1 (es) 2008-04-03 2014-08-15 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
KR20200118243A (ko) 2008-08-06 2020-10-14 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
WO2010029089A2 (en) 2008-09-10 2010-03-18 Boehringer Ingelheim International Gmbh Combination therapy for the treatment of diabetes and related conditions
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
WO2010072776A1 (en) 2008-12-23 2010-07-01 Boehringer Ingelheim International Gmbh Salt forms of organic compound
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
CN102753161A (zh) 2009-11-27 2012-10-24 贝林格尔.英格海姆国际有限公司 基因型糖尿病患者利用dpp-iv抑制剂例如利拉利汀的治疗
ES2935300T3 (es) 2010-05-05 2023-03-03 Boehringer Ingelheim Int Combiterapia
CN106975074A (zh) 2010-06-24 2017-07-25 勃林格殷格翰国际有限公司 糖尿病治疗
US9034883B2 (en) 2010-11-15 2015-05-19 Boehringer Ingelheim International Gmbh Vasoprotective and cardioprotective antidiabetic therapy
WO2013010964A1 (en) 2011-07-15 2013-01-24 Boehringer Ingelheim International Gmbh Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
WO2013171167A1 (en) 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
US9526728B2 (en) 2014-02-28 2016-12-27 Boehringer Ingelheim International Gmbh Medical use of a DPP-4 inhibitor
BR112018072401A2 (pt) 2016-06-10 2019-02-19 Boehringer Ingelheim International Gmbh combinações de linagliptina e metformina

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758583A (en) * 1984-03-19 1988-07-19 The Rockefeller University Method and agents for inhibiting protein aging

Also Published As

Publication number Publication date
PT888293E (pt) 2002-07-31
JP2000502684A (ja) 2000-03-07
WO1997023447A1 (en) 1997-07-03
TW502012B (en) 2002-09-11
CN1209117A (zh) 1999-02-24
NO982976L (no) 1998-08-26
ES2174132T3 (es) 2002-11-01
NO982976D0 (no) 1998-06-26
CA2241746A1 (en) 1997-07-03
AU1356097A (en) 1997-07-17
DK0888293T3 (da) 2002-04-22
BR9612304A (pt) 1999-07-13
NZ326238A (en) 1999-11-29
EP0888293B1 (de) 2002-03-27
AU720796B2 (en) 2000-06-15
DE69620253T2 (de) 2002-09-19
DE69620253D1 (en) 2002-05-02
EP0888293A1 (de) 1999-01-07

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