ATE208209T1 - Die kombination des wachstumhormones und des insulinähnlichen wachstumsfaktors-i zur behandlung von kongestivem herzversagen - Google Patents

Die kombination des wachstumhormones und des insulinähnlichen wachstumsfaktors-i zur behandlung von kongestivem herzversagen

Info

Publication number
ATE208209T1
ATE208209T1 AT95914882T AT95914882T ATE208209T1 AT E208209 T1 ATE208209 T1 AT E208209T1 AT 95914882 T AT95914882 T AT 95914882T AT 95914882 T AT95914882 T AT 95914882T AT E208209 T1 ATE208209 T1 AT E208209T1
Authority
AT
Austria
Prior art keywords
combination
mammal
heart failure
congestive heart
insulin
Prior art date
Application number
AT95914882T
Other languages
English (en)
Inventor
Ross G Clark
Hongkui Jin
Nicholas F Paoni
Renhui Yang
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/284,859 external-priority patent/US5661122A/en
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE208209T1 publication Critical patent/ATE208209T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
AT95914882T 1994-04-15 1995-03-30 Die kombination des wachstumhormones und des insulinähnlichen wachstumsfaktors-i zur behandlung von kongestivem herzversagen ATE208209T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22792394A 1994-04-15 1994-04-15
US08/284,859 US5661122A (en) 1994-04-15 1994-08-02 Treatment of congestive heart failure
US08/333,909 US5610134A (en) 1994-04-15 1994-11-03 Treatment of congestive heart failure
PCT/US1995/003755 WO1995028174A1 (en) 1994-04-15 1995-03-30 The combination of growth hormone and insulin-like growth factor, for treating congestive heart failure

Publications (1)

Publication Number Publication Date
ATE208209T1 true ATE208209T1 (de) 2001-11-15

Family

ID=27397790

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95914882T ATE208209T1 (de) 1994-04-15 1995-03-30 Die kombination des wachstumhormones und des insulinähnlichen wachstumsfaktors-i zur behandlung von kongestivem herzversagen

Country Status (13)

Country Link
US (1) US5610134A (de)
EP (1) EP0755265B1 (de)
JP (1) JP3473623B2 (de)
AT (1) ATE208209T1 (de)
AU (1) AU691273B2 (de)
CA (1) CA2185998C (de)
DE (1) DE69523747T2 (de)
DK (1) DK0755265T3 (de)
ES (1) ES2167427T3 (de)
HK (1) HK1003418A1 (de)
LV (1) LV12966B (de)
PT (1) PT755265E (de)
WO (1) WO1995028174A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3182307B2 (ja) * 1994-12-27 2001-07-03 株式会社荏原製作所 全周流型ポンプ
US5741776A (en) * 1995-05-22 1998-04-21 Genentech, Inc. Method of administration of IGF-I
TW432073B (en) 1995-12-28 2001-05-01 Pfizer Pyrazolopyridine compounds
AU2334097A (en) * 1996-03-21 1997-10-10 Merck & Co., Inc. 4-spiroindoline piperidines promote release of growth hormone
US6306826B1 (en) 1997-06-04 2001-10-23 The Regents Of The University Of California Treatment of heart failure with growth hormone
US6015384A (en) * 1998-08-31 2000-01-18 Acuson Corporation Ultrasonic system and method for tissue viability imaging
SE9901634D0 (sv) * 1999-05-05 1999-05-05 Sahltech Ab Treatment of myocardial infarction with a substance related to the growth hormone axis
JP2003504343A (ja) * 1999-07-12 2003-02-04 ジェネンテック・インコーポレーテッド 腫瘍壊死因子リガンド/レセプター相同体による血管形成及び心血管形成の促進と抑制
CA2378949C (en) * 1999-07-12 2015-03-31 Grandis Biotech Gmbh Growth hormone formulations
WO2001059100A2 (en) * 2000-02-11 2001-08-16 Genentech, Inc. Inhibitor of hepatocyte growth factor activator for use in modulation of angiogenesis and cardiovascularization
FR2805051B1 (fr) * 2000-02-14 2002-12-06 Geophysique Cie Gle Methode de surveillance sismique d'une zone souterraine par utilisation simultanee de plusieurs sources vibrosismiques
EP2792747A1 (de) 2000-06-23 2014-10-22 Genentech, Inc. Zusammensetzungen und Verfahren zur Diagnose und Behandlung von Erkrankungen in Verbindung mit Angiogenese
CA2648051A1 (en) 2000-06-23 2002-01-03 Genentech, Inc. Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
US7547674B2 (en) 2001-06-06 2009-06-16 New York Medical College Methods and compositions for the repair and/or regeneration of damaged myocardium
US7862810B2 (en) 2000-07-31 2011-01-04 New York Medical College Methods and compositions for the repair and/or regeneration of damaged myocardium
WO2002009650A2 (en) 2000-07-31 2002-02-07 New York Medical College Methods and compositions for the repair and/or regeneration of damaged myocardium
US20030224984A1 (en) * 2001-06-20 2003-12-04 Genentech, Inc. Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
US6607517B1 (en) 2001-08-24 2003-08-19 Radiant Medical, Inc. Method of inotropic treatment of heart disease using hypothermia
KR20050090430A (ko) 2002-12-31 2005-09-13 알투스 파마슈티컬스 인코포레이티드 인간 성장 호르몬 결정 및 이것의 제조 방법
US20080103457A1 (en) * 2005-01-11 2008-05-01 Heart Failure Technologies, Inc. University Enterprise Laboratories (Uel) Method and System for Treating Heart Failure
AU2008323719B2 (en) 2007-11-09 2013-04-04 New York Medical College Methods for the repair and/or regeneration of damaged myocardium using variants of hepatocyte growth factor
AU2008334058B2 (en) 2007-11-30 2014-07-10 New York Medical College Compositions comprising vascular and myocyte progenitor cells and methods of their use
US8512696B2 (en) 2007-11-30 2013-08-20 Autologous, Llc Methods of isolating non-senescent cardiac stem cells and uses thereof
EP2225362A1 (de) 2007-11-30 2010-09-08 New York Medical College Verfahren zur verminderung von transplantatabstossung und herz-allotransplantat-vaskulopathie mittels implantieren autologer stammzellen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126324A (en) * 1990-06-07 1992-06-30 Genentech, Inc. Method of enhancing growth in patients using combination therapy
WO1992007578A1 (en) * 1990-10-25 1992-05-14 Genentech, Inc. Use of protective agents against reactive oxygen species
SE9100099D0 (sv) * 1991-01-11 1991-01-11 Kabi Pharmacia Ab Use of growth factor
SE9101840L (sv) * 1991-06-14 1992-12-15 Kabi Pharmacia Ny medicinsk anvaendning
WO1993000109A1 (en) * 1991-06-28 1993-01-07 Genentech, Inc. Method of stimulating immune response using growth hormone
US5202119A (en) * 1991-06-28 1993-04-13 Genentech, Inc. Method of stimulating immune response

Also Published As

Publication number Publication date
EP0755265B1 (de) 2001-11-07
HK1003418A1 (en) 1998-10-30
JP3473623B2 (ja) 2003-12-08
ES2167427T3 (es) 2002-05-16
US5610134A (en) 1997-03-11
AU2195695A (en) 1995-11-10
DE69523747D1 (de) 2001-12-13
LV12966B (en) 2003-05-20
PT755265E (pt) 2002-04-29
DK0755265T3 (da) 2002-03-04
CA2185998C (en) 2011-02-22
CA2185998A1 (en) 1995-10-26
DE69523747T2 (de) 2002-08-01
EP0755265A1 (de) 1997-01-29
AU691273B2 (en) 1998-05-14
WO1995028174A1 (en) 1995-10-26
JPH09512008A (ja) 1997-12-02

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