ATE205203T1 - D4t polymorphe form i verfahren - Google Patents

D4t polymorphe form i verfahren

Info

Publication number
ATE205203T1
ATE205203T1 AT96304030T AT96304030T ATE205203T1 AT E205203 T1 ATE205203 T1 AT E205203T1 AT 96304030 T AT96304030 T AT 96304030T AT 96304030 T AT96304030 T AT 96304030T AT E205203 T1 ATE205203 T1 AT E205203T1
Authority
AT
Austria
Prior art keywords
polymorphoic
approved
aids
iii
obtaining
Prior art date
Application number
AT96304030T
Other languages
English (en)
Inventor
Rajesh Babulal Gandhi
Joseph Ballard Bogardus
Peter Michael Garofalo
Timothy Richard Marr
Robert Kevin Perrone
Murray Arthur Kaplan
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE205203T1 publication Critical patent/ATE205203T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT96304030T 1995-06-05 1996-06-04 D4t polymorphe form i verfahren ATE205203T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/465,208 US5608048A (en) 1995-06-05 1995-06-05 d4 T polymorphic Form 1 process

Publications (1)

Publication Number Publication Date
ATE205203T1 true ATE205203T1 (de) 2001-09-15

Family

ID=23846880

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96304030T ATE205203T1 (de) 1995-06-05 1996-06-04 D4t polymorphe form i verfahren

Country Status (18)

Country Link
US (1) US5608048A (de)
EP (1) EP0749969B1 (de)
JP (1) JP4208976B2 (de)
KR (1) KR100375957B1 (de)
CN (1) CN1058723C (de)
AT (1) ATE205203T1 (de)
AU (1) AU694653B2 (de)
CA (1) CA2176181C (de)
DE (1) DE69614936T2 (de)
DK (1) DK0749969T3 (de)
ES (1) ES2160768T3 (de)
GR (1) GR3036768T3 (de)
HU (1) HU222285B1 (de)
IL (1) IL118527A (de)
MX (1) MX9601957A (de)
PT (1) PT749969E (de)
SG (1) SG43372A1 (de)
TW (1) TW336937B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001285197A1 (en) * 2000-09-06 2002-03-22 Bristol-Myers Squibb Company Stavudine polymorphic form 1 process
US7825106B2 (en) * 2003-09-03 2010-11-02 Agi Therapeutics Ltd. Modified release formulations and methods of treating inflammatory bowel disease
US7737133B2 (en) * 2003-09-03 2010-06-15 Agi Therapeutics Ltd. Formulations and methods of treating inflammatory bowel disease
US20050131224A1 (en) * 2003-12-15 2005-06-16 Cti Pet Systems, Inc. Method for preparing radiolabeled thymidine
US7160537B2 (en) * 2003-12-15 2007-01-09 Siemens Medical Solutions Usa, Inc. Method for preparing radiolabeled thymidine having low chromophoric byproducts
WO2007099389A1 (en) * 2005-07-11 2007-09-07 Aurobindo Pharma Limited A new improved process for the preparation of stavudine form i
ITMI20060360A1 (it) * 2006-02-28 2007-09-01 Clariant Lsm Italia Spa Novel method for the preparation of stavudine polymorphic form 1 and form ii
EP2674517B1 (de) * 2011-02-08 2018-10-03 Japan Agency for Marine-Earth Science and Technology Verfahren zur herstellung eines calcit-einkristalls

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen
US4978655A (en) * 1986-12-17 1990-12-18 Yale University Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses
US4904770A (en) * 1988-03-24 1990-02-27 Bristol-Myers Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides
US5539099A (en) * 1993-11-15 1996-07-23 Bristol-Myers Squibb Company Process for large-scale preparation of 2',3'-didehydro-2',3'-dideoxynucleosides
US5672698A (en) * 1993-11-15 1997-09-30 Bristol-Myers Squibb Co. Preparation of 2',3'-didehydro-3'-deoxythymidine from 5-methyluridine
US5608049A (en) * 1995-03-10 1997-03-04 Bristol-Myers Squibb Company Preparation of d4T from 5-methyluridine

Also Published As

Publication number Publication date
JP4208976B2 (ja) 2009-01-14
JPH08333364A (ja) 1996-12-17
KR970001369A (ko) 1997-01-24
PT749969E (pt) 2001-12-28
EP0749969A3 (de) 1997-03-19
DK0749969T3 (da) 2001-11-26
IL118527A0 (en) 1996-10-16
EP0749969B1 (de) 2001-09-05
HU9601517D0 (en) 1996-07-29
DE69614936D1 (de) 2001-10-11
AU5469296A (en) 1996-12-19
MX9601957A (es) 1997-08-30
US5608048A (en) 1997-03-04
TW336937B (en) 1998-07-21
EP0749969A2 (de) 1996-12-27
HU222285B1 (hu) 2003-05-28
KR100375957B1 (ko) 2003-12-31
CN1058723C (zh) 2000-11-22
CN1145903A (zh) 1997-03-26
AU694653B2 (en) 1998-07-23
HUP9601517A2 (en) 1997-05-28
GR3036768T3 (en) 2002-01-31
ES2160768T3 (es) 2001-11-16
HK1003435A1 (en) 1998-10-30
SG43372A1 (en) 1997-10-17
CA2176181C (en) 2007-03-13
IL118527A (en) 2000-07-16
DE69614936T2 (de) 2002-04-25
HUP9601517A3 (en) 2000-03-28
CA2176181A1 (en) 1996-12-06

Similar Documents

Publication Publication Date Title
ATE188460T1 (de) Verfahren zum herstellen von derivaten des 4a,5,9,10,11,12,-hexahydro-6h-benzofuro(3a,3,2- ef)(2)benzazepins
DE69936890D1 (de) Vorrichtung zur Behandlung von Ischämie
DE69613770D1 (de) Verfahren zur Herstellung von Ethylen-Propylen-Copolymeren
DE69707033D1 (de) Verfahren zur Behandlung von Gasen die Organohalogenzusammensetzungen enthalten
DE69516438D1 (de) Verfahren zur Herstellung von chlororganischen Silizium-Verbindungen
ATE227723T1 (de) Eintopfverfahren zur herstellung von 2- oxazolidinonderivate
DE69022269D1 (de) Verfahren zur thermischen Behandlung von Silizium.
DE69201530D1 (de) Verfahren zur Herstellung von Ethylen-Propylen-Blockkopolymerisate.
ATE205203T1 (de) D4t polymorphe form i verfahren
DK0785949T3 (da) Fremgangsmåde til oprensning af keratinocytvækstfaktorer
DE69918605D1 (de) Verfahren zur Herstellung von Kaliumoxonat
DE69300901D1 (de) Verfahren zur Reinigung von 1,1,1,2-Tetrafluorethan.
ATE251132T1 (de) Verfahren zur herstellung von s-aryl-l-cystein und derivate
NO903338L (no) Fremgangsmaate for mikrobiologisk fremstilling av l-carnitin.
ATE129238T1 (de) Verfahren zur herstellung von substituierten pyridylalkylketonen.
DE59611076D1 (de) Verfahren zur herstellung von 5,6-dihydro-1,3-oxazinen
ATE181556T1 (de) Darstellung von d4t aus 5-methyluridin
DE69909048D1 (de) Verfahren zur Herstellung von Raffinosekristallen
DE59806309D1 (de) Verfahren zur Herstellung von 1,2,3,6-Tetrahydro-2,2,6,6,-tetramethylpyridin-N-oxyl
DE69500362D1 (de) Verfahren zur Herstellung 5,6-dihydroxyindol-Derivate ausgehend von Dopa
DE59904904D1 (de) Verfahren zur Herstellung von Phenyldichloro-1,3,5-triazinverbindungen
DE59812729D1 (de) Verfahren zur Herstellung von 1,3-Dioxanverbindungen
ATE208388T1 (de) Eintopfverfahren zur herstellung von 2- oxazolidinonderivate
ATE168110T1 (de) Verfahren und zwischenprodukte zur herstellung von 5-oxaspiro (2.4> heptan-6-on
DE69501455D1 (de) Verfahren zur Herstellung von Silizium-Oxy-Karbid

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee