ATE202481T1 - Reines, biologisch aktives colistin, seine bestandteile und eine colistin-zubereitung zur behandlung von entzündungen der atemwege - Google Patents

Reines, biologisch aktives colistin, seine bestandteile und eine colistin-zubereitung zur behandlung von entzündungen der atemwege

Info

Publication number
ATE202481T1
ATE202481T1 AT97954029T AT97954029T ATE202481T1 AT E202481 T1 ATE202481 T1 AT E202481T1 AT 97954029 T AT97954029 T AT 97954029T AT 97954029 T AT97954029 T AT 97954029T AT E202481 T1 ATE202481 T1 AT E202481T1
Authority
AT
Austria
Prior art keywords
colistine
biologically active
preparation
treatment
components
Prior art date
Application number
AT97954029T
Other languages
German (de)
English (en)
Inventor
Donald R Vandevanter
Alan B Montgomery
Original Assignee
Pathogenesis Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/799,200 external-priority patent/US5821623A/en
Application filed by Pathogenesis Corp filed Critical Pathogenesis Corp
Application granted granted Critical
Publication of ATE202481T1 publication Critical patent/ATE202481T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
AT97954029T 1996-11-15 1997-11-13 Reines, biologisch aktives colistin, seine bestandteile und eine colistin-zubereitung zur behandlung von entzündungen der atemwege ATE202481T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3093996P 1996-11-15 1996-11-15
US08/799,200 US5821623A (en) 1996-02-26 1997-02-13 Multi-layer gate structure
PCT/US1997/021829 WO1998020836A2 (en) 1996-11-15 1997-11-13 Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections

Publications (1)

Publication Number Publication Date
ATE202481T1 true ATE202481T1 (de) 2001-07-15

Family

ID=26706611

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97954029T ATE202481T1 (de) 1996-11-15 1997-11-13 Reines, biologisch aktives colistin, seine bestandteile und eine colistin-zubereitung zur behandlung von entzündungen der atemwege

Country Status (7)

Country Link
EP (1) EP0920324B1 (enExample)
JP (2) JP2001505557A (enExample)
AT (1) ATE202481T1 (enExample)
AU (1) AU730546B2 (enExample)
CA (1) CA2242335A1 (enExample)
DE (1) DE69705414T2 (enExample)
WO (1) WO1998020836A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ505651A (en) * 1998-01-16 2003-08-29 Takeda Chemical Industries Ltd Sustained release composition comprising biologically active substance, hydroxynaphthoic acid and biodegradable polymer
GB9820746D0 (en) * 1998-09-23 1998-11-18 Pharmax Limited Micronised pharmaceutical compositions
CA2635489A1 (en) * 2000-02-11 2001-08-16 Respironics Respiratory Drug Delivery (Uk) Ltd Drug delivery apparatus
US8820316B2 (en) 2000-02-11 2014-09-02 Respironics Respiratory Drug Delivery (Uk) Ltd Drug delivery apparatus
EP1129705A1 (en) * 2000-02-17 2001-09-05 Rijksuniversiteit te Groningen Powder formulation for inhalation
EP1488819A1 (en) 2003-06-16 2004-12-22 Rijksuniversiteit te Groningen Dry powder inhaler and method for pulmonary inhalation of dry powder
WO2008020474A1 (en) * 2006-08-15 2008-02-21 Meiji Seika Kaisha Ltd. Method of producing colistin bulk powder
CN102596987B (zh) * 2009-10-30 2014-06-25 埃克斯利亚制药有限公司 用于纯化粘菌素的方法和纯化的粘菌素组分
CN102190711A (zh) * 2010-01-22 2011-09-21 上海医药工业研究院 多黏菌素e组合物及其制备方法和用途
CA2895910C (en) 2013-01-11 2021-12-21 Xellia Pharmaceuticals Aps Polymyxins, compositions, methods of making and methods of use
JP6508655B2 (ja) 2014-01-24 2019-05-08 Ｅａファーマ株式会社 メガリン拮抗剤
FR3016888B1 (fr) 2014-01-27 2021-01-22 Centre Nat Rech Scient Synthetases de la colistine et cluster de genes correspondants
PT3166960T (pt) 2014-07-09 2019-10-25 Xellia Pharmaceuticals Aps Polimixinas de baixa substituição e composições das mesmas.
GB201416788D0 (en) * 2014-09-23 2014-11-05 Univ Glasgow Therapeutic applications for pyocins
PL3200762T3 (pl) * 2014-10-03 2019-08-30 Xellia Pharmaceuticals Aps Urządzenie do inhalacji
CN106794221B (zh) * 2014-10-03 2021-12-10 埃克斯利亚制药有限公司 组合物
EP3366284A1 (en) * 2017-02-27 2018-08-29 Zambon S.p.A. Association of n-acetylcysteine and colistin for use in bacterial infections
CN116744974A (zh) * 2021-01-01 2023-09-12 普渡研究基金会 用于吸入的多黏菌素的共制剂

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2124060B1 (enExample) * 1971-02-02 1974-04-12 Rhone Poulenc Sa

Also Published As

Publication number Publication date
EP0920324A2 (en) 1999-06-09
JP2007302698A (ja) 2007-11-22
DE69705414T2 (de) 2002-05-02
EP0920324A4 (enExample) 1999-06-09
EP0920324B1 (en) 2001-06-27
AU730546B2 (en) 2001-03-08
WO1998020836A3 (en) 1998-07-09
DE69705414D1 (de) 2001-08-02
WO1998020836A2 (en) 1998-05-22
AU5790998A (en) 1998-06-03
CA2242335A1 (en) 1998-05-22
JP2001505557A (ja) 2001-04-24

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