ATE199375T1 - Verfahren zur herstellung von 3-(2-(4-(3-chlor-2- methylphenyl)-1- piperazinyl) ethyl)-5,6- dimethoxy-1-(4-imidazolylmethyl)-1h-indazol- dihydrochlorid-3.5-hydrat. - Google Patents

Verfahren zur herstellung von 3-(2-(4-(3-chlor-2- methylphenyl)-1- piperazinyl) ethyl)-5,6- dimethoxy-1-(4-imidazolylmethyl)-1h-indazol- dihydrochlorid-3.5-hydrat.

Info

Publication number
ATE199375T1
ATE199375T1 AT95936786T AT95936786T ATE199375T1 AT E199375 T1 ATE199375 T1 AT E199375T1 AT 95936786 T AT95936786 T AT 95936786T AT 95936786 T AT95936786 T AT 95936786T AT E199375 T1 ATE199375 T1 AT E199375T1
Authority
AT
Austria
Prior art keywords
hydrate
dihydrochloride
imidazolylmethyl
dimethoxy
methylphenyl
Prior art date
Application number
AT95936786T
Other languages
English (en)
Inventor
Kenjiro Yamamoto
Akihiko Miyadera
Hiroaki Kitaoka
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of ATE199375T1 publication Critical patent/ATE199375T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
AT95936786T 1994-11-14 1995-11-14 Verfahren zur herstellung von 3-(2-(4-(3-chlor-2- methylphenyl)-1- piperazinyl) ethyl)-5,6- dimethoxy-1-(4-imidazolylmethyl)-1h-indazol- dihydrochlorid-3.5-hydrat. ATE199375T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27820494 1994-11-14
PCT/JP1995/002317 WO1996015124A1 (fr) 1994-11-14 1995-11-14 Hydrate a usage medicinal

Publications (1)

Publication Number Publication Date
ATE199375T1 true ATE199375T1 (de) 2001-03-15

Family

ID=17594052

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95936786T ATE199375T1 (de) 1994-11-14 1995-11-14 Verfahren zur herstellung von 3-(2-(4-(3-chlor-2- methylphenyl)-1- piperazinyl) ethyl)-5,6- dimethoxy-1-(4-imidazolylmethyl)-1h-indazol- dihydrochlorid-3.5-hydrat.

Country Status (16)

Country Link
US (1) US5948913A (de)
EP (1) EP0792879B1 (de)
KR (1) KR100372188B1 (de)
CN (1) CN1067998C (de)
AT (1) ATE199375T1 (de)
AU (1) AU698464B2 (de)
CA (1) CA2205206A1 (de)
DE (1) DE69520225T2 (de)
DK (1) DK0792879T3 (de)
ES (1) ES2156605T3 (de)
FI (1) FI972035A (de)
GR (1) GR3035820T3 (de)
NO (1) NO972190L (de)
PT (1) PT792879E (de)
RU (1) RU2152941C1 (de)
WO (1) WO1996015124A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE510650C2 (sv) * 1997-05-30 1999-06-14 Astra Ab Ny förening
WO1999024432A1 (en) 1997-11-12 1999-05-20 Mitsubishi Chemical Corporation Purine derivatives and medicine containing the same as the active ingredient
US6660745B1 (en) * 1999-05-11 2003-12-09 Mitsubishi Chemical Corporation Purine derivative dihydrate, drugs containing the same as the active ingredient and intermediate in the production thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3362956A (en) * 1965-08-19 1968-01-09 Sterling Drug Inc 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines
WO1994007874A1 (en) * 1992-10-06 1994-04-14 Ciba-Geigy Ag Novel thiosemicarbazonethiones
RU2124511C1 (ru) * 1993-05-14 1999-01-10 Фармасьютикал Ко., Лтд Производные пиперазина
US5681954A (en) * 1993-05-14 1997-10-28 Daiichi Pharmaceutical Co., Ltd. Piperazine derivatives
PH31213A (en) * 1993-05-25 1998-05-05 Daiichi Seiyaku Co Drug for neuroprotection.
JPH0741431A (ja) * 1993-05-25 1995-02-10 Dai Ichi Seiyaku Co Ltd 脳保護薬

Also Published As

Publication number Publication date
NO972190D0 (no) 1997-05-13
CN1171786A (zh) 1998-01-28
RU2152941C1 (ru) 2000-07-20
DE69520225T2 (de) 2001-10-11
DE69520225D1 (de) 2001-04-05
AU698464B2 (en) 1998-10-29
CA2205206A1 (en) 1996-05-23
PT792879E (pt) 2001-08-30
WO1996015124A1 (fr) 1996-05-23
FI972035A (fi) 1997-07-11
DK0792879T3 (da) 2001-03-26
ES2156605T3 (es) 2001-07-01
GR3035820T3 (en) 2001-07-31
FI972035A0 (fi) 1997-05-13
KR100372188B1 (ko) 2003-05-12
CN1067998C (zh) 2001-07-04
EP0792879A4 (de) 1998-02-25
EP0792879B1 (de) 2001-02-28
US5948913A (en) 1999-09-07
AU3856595A (en) 1996-06-06
KR970707118A (ko) 1997-12-01
EP0792879A1 (de) 1997-09-03
NO972190L (no) 1997-07-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee