ATE198044T1 - Hydroperoxeicosatetraensäure derivate enthaltende zusammensetzungen und verfahren zur verwendung zur behandlung des trockenen auges - Google Patents

Hydroperoxeicosatetraensäure derivate enthaltende zusammensetzungen und verfahren zur verwendung zur behandlung des trockenen auges

Info

Publication number
ATE198044T1
ATE198044T1 AT96928944T AT96928944T ATE198044T1 AT E198044 T1 ATE198044 T1 AT E198044T1 AT 96928944 T AT96928944 T AT 96928944T AT 96928944 T AT96928944 T AT 96928944T AT E198044 T1 ATE198044 T1 AT E198044T1
Authority
AT
Austria
Prior art keywords
methods
compositions containing
hydroperoxeicosatetraenacid
derivatives
dry eye
Prior art date
Application number
AT96928944T
Other languages
English (en)
Inventor
John M Yanni
Daniel A Gamache
Steven T Miller
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Application granted granted Critical
Publication of ATE198044T1 publication Critical patent/ATE198044T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT96928944T 1995-10-31 1996-08-19 Hydroperoxeicosatetraensäure derivate enthaltende zusammensetzungen und verfahren zur verwendung zur behandlung des trockenen auges ATE198044T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/551,021 US5696166A (en) 1995-10-31 1995-10-31 Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
PCT/US1996/013441 WO1997016179A1 (en) 1995-10-31 1996-08-19 Compositions containing hydroperoxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders

Publications (1)

Publication Number Publication Date
ATE198044T1 true ATE198044T1 (de) 2000-12-15

Family

ID=24199512

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96928944T ATE198044T1 (de) 1995-10-31 1996-08-19 Hydroperoxeicosatetraensäure derivate enthaltende zusammensetzungen und verfahren zur verwendung zur behandlung des trockenen auges

Country Status (13)

Country Link
US (1) US5696166A (de)
EP (1) EP0858330B1 (de)
JP (1) JPH11515024A (de)
AT (1) ATE198044T1 (de)
AU (1) AU706373B2 (de)
CA (1) CA2234367C (de)
DE (1) DE69611251T2 (de)
DK (1) DK0858330T3 (de)
ES (1) ES2152556T3 (de)
GR (1) GR3035438T3 (de)
HK (1) HK1013194A1 (de)
PT (1) PT858330E (de)
WO (1) WO1997016179A1 (de)

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DE60020591T2 (de) 1999-11-09 2005-11-10 Alcon Inc. Benzenoidderivate von 15-hydroxyeicosatetraesäure und verfahren zur verwendung zur behandlung des trockenen auges
US6803385B2 (en) 1999-11-09 2004-10-12 Alcon, Inc. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
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US6353032B1 (en) * 1999-11-09 2002-03-05 Alcon Universal Ltd. Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
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US6552084B2 (en) 1999-11-09 2003-04-22 Alcon Universal Ltd. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
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US20020077358A1 (en) * 2000-10-23 2002-06-20 Alcon Universal Ltd. Use of hydroperoxyeicosatetraenoic acid derivatives following refractive surgery
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US6872382B1 (en) 2001-05-21 2005-03-29 Alcon, Inc. Use of selective PDE IV inhibitors to treat dry eye disorders
PL367097A1 (en) * 2001-05-21 2005-02-21 Alcon, Inc. Method of treating dry eye disorders
US7112588B2 (en) * 2001-05-21 2006-09-26 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
CA2447909C (en) 2001-05-21 2011-04-05 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
US6645994B1 (en) 2001-06-01 2003-11-11 Alcon, Inc. Method of treating dry eye disorders
US6750250B1 (en) * 2001-07-12 2004-06-15 Alcon, Inc. 11,12-oxidoarachidonic acid derivatives and methods of their use in treating dry eye disorders
US20030109488A1 (en) * 2001-10-11 2003-06-12 Alcon, Inc. Methods for treating dry eye
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WO2003030894A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye
WO2003105831A1 (en) * 2002-06-14 2003-12-24 Alcon, Inc. Use of hydroxyeicosatetraenoic acid compounds to treat ophthalmic inflammatory disorders
US20040002514A1 (en) * 2002-06-14 2004-01-01 Alcon, Inc. Topical use of hydroxyeicosatetraenoic acid compounds to treat psoriasis
FR2843026B1 (fr) * 2002-08-02 2006-01-06 Goemar Lab Sa Nouveau medicament
EP1542768A1 (de) * 2002-09-20 2005-06-22 Alcon, Inc. Verwendung von zytokin-synthesehemmern zur behandlung von erkrankungen mit trockenem auge
WO2004060274A2 (en) * 2002-12-20 2004-07-22 Alcon, Inc. Treatment of dry eye by restoring 15-lipoxygenase activity to ocular surface cells
WO2004093878A1 (en) 2003-04-16 2004-11-04 Alcon, Inc. Use of fused pyridazine derivatives for treating dry eye disorders
US8455016B2 (en) 2004-03-12 2013-06-04 Melbj Holdings, Llc Treatment for meibomian gland dysfunction or obstruction
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US7745461B1 (en) 2006-02-27 2010-06-29 Alcon Research, Ltd. Method of treating dry eye disorders
EP2175858B1 (de) * 2007-07-11 2014-09-10 Pfizer Inc. Pharmazeutische zusammensetzungen und verfahren zur behandlung von trockenem auge
US20090048368A1 (en) * 2007-08-13 2009-02-19 Bash Thomas F Polyolefin compositions comprising bio-based starch materials
AU2014201375B2 (en) * 2007-10-12 2015-11-05 Resolvyx Pharmaceuticals, Inc. Omega-3 fatty acids, hydroxy polyunsaturated fatty acids, lipoxin compounds, or oxylipin compounds for the treatment of ophthalmic conditions
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Also Published As

Publication number Publication date
AU6851696A (en) 1997-05-22
ES2152556T3 (es) 2001-02-01
CA2234367C (en) 2002-06-04
AU706373B2 (en) 1999-06-17
DK0858330T3 (da) 2001-01-02
DE69611251T2 (de) 2001-04-05
HK1013194A1 (en) 1999-08-20
EP0858330B1 (de) 2000-12-13
WO1997016179A1 (en) 1997-05-09
DE69611251D1 (de) 2001-01-18
CA2234367A1 (en) 1997-05-09
EP0858330A1 (de) 1998-08-19
JPH11515024A (ja) 1999-12-21
GR3035438T3 (en) 2001-05-31
US5696166A (en) 1997-12-09
PT858330E (pt) 2001-03-30

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