ATE197903T1 - Peptid-kohlenwasserstoff konjugate, welche t-zell immunität bewirken - Google Patents
Peptid-kohlenwasserstoff konjugate, welche t-zell immunität bewirkenInfo
- Publication number
- ATE197903T1 ATE197903T1 AT93912042T AT93912042T ATE197903T1 AT E197903 T1 ATE197903 T1 AT E197903T1 AT 93912042 T AT93912042 T AT 93912042T AT 93912042 T AT93912042 T AT 93912042T AT E197903 T1 ATE197903 T1 AT E197903T1
- Authority
- AT
- Austria
- Prior art keywords
- carbohydrate
- peptide
- cell immunity
- effect
- immunogenic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/605—MHC molecules or ligands thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9201338A SE9201338D0 (sv) | 1992-04-28 | 1992-04-28 | New active compounds |
SE9202553A SE9202553D0 (sv) | 1992-09-07 | 1992-09-07 | New active compounds ii |
SE9203897A SE9203897D0 (sv) | 1992-12-23 | 1992-12-23 | New active compounds iii |
SE9301141A SE9301141D0 (sv) | 1993-04-06 | 1993-04-06 | New active compounds iv |
PCT/SE1993/000353 WO1993021948A1 (en) | 1992-04-28 | 1993-04-23 | Peptide-carbohydrate conjugates generating t-cell immunity |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE197903T1 true ATE197903T1 (de) | 2000-12-15 |
Family
ID=27484749
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93912042T ATE197903T1 (de) | 1992-04-28 | 1993-04-23 | Peptid-kohlenwasserstoff konjugate, welche t-zell immunität bewirken |
Country Status (19)
Country | Link |
---|---|
US (2) | US5807559A (de) |
EP (1) | EP0675733B1 (de) |
JP (1) | JPH07506358A (de) |
CN (1) | CN1096032A (de) |
AT (1) | ATE197903T1 (de) |
AU (1) | AU676679B2 (de) |
CA (1) | CA2134097A1 (de) |
DE (1) | DE69329735T2 (de) |
DK (1) | DK0675733T3 (de) |
ES (1) | ES2155070T3 (de) |
GR (1) | GR3035501T3 (de) |
IL (1) | IL105503A (de) |
IS (1) | IS4010A (de) |
MA (1) | MA22885A1 (de) |
MY (1) | MY108864A (de) |
PT (1) | PT675733E (de) |
SI (1) | SI9300223A (de) |
TN (1) | TNSN93045A1 (de) |
WO (1) | WO1993021948A1 (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6083929A (en) * | 1991-05-06 | 2000-07-04 | The Biomembrane Institute | Extended type 1 chain glycosphingolipids as tumor-associated antigens |
DE4436164A1 (de) * | 1994-10-10 | 1996-04-11 | Hoechst Ag | Neue Kohlenhydratkonjugate als Inhibitoren der Zelladhäsion |
US6548643B1 (en) | 1994-11-16 | 2003-04-15 | Austin Research Institute | Antigen carbohydrate compounds and their use in immunotherapy |
US6841543B1 (en) * | 1996-01-31 | 2005-01-11 | President And Fellows Of Harvard College | Methods of inhibiting production of T helper type 2 cytokines in human immune cells |
US6218363B1 (en) * | 1996-08-28 | 2001-04-17 | Thomas Jefferson University | MHC peptides and methods of use |
WO1998015286A1 (en) * | 1996-10-08 | 1998-04-16 | La Jolla Institute For Allergy & Immunology | Carbohydrate-specific cytolytic t cells |
US20070237785A1 (en) * | 1997-03-27 | 2007-10-11 | Institut Pasteur | Multiple antigen glycopeptide carbohydrate, vaccine comprising the same and use thereof |
ES2265162T3 (es) * | 1997-03-27 | 2007-02-01 | Institut Pasteur | Carbohidrato glucopeptido de antigeno multiple, vacuna que comprende el mismo y su utilizacion. |
US7550146B2 (en) * | 1997-04-16 | 2009-06-23 | Sloan-Kettering Institute For Cancer Research | Glycopeptide conjugates and uses thereof |
JP4308918B2 (ja) | 1997-04-16 | 2009-08-05 | スローン−ケッタリング インスティトゥート フォア キャンサー リサーチ | (2,6)−STエピトープクラスターを有するα−O−結合複合糖質、その製造方法および使用 |
AUPO732997A0 (en) * | 1997-06-12 | 1997-07-03 | Csl Limited | Ganglioside immunostimulating complexes and uses thereof |
WO1999048515A1 (en) * | 1998-03-25 | 1999-09-30 | Sloan-Kettering Institute For Cancer Research | Trimeric antigenic o-linked glycopeptide conjugates, methods of preparation and uses thereof |
EP1068296B1 (de) | 1998-03-31 | 2011-08-10 | Geron Corporation | Zusammensetzungen zur auslösung einer immunantwort gegen ein telomerase antigen |
US7402307B2 (en) * | 1998-03-31 | 2008-07-22 | Geron Corporation | Method for identifying and killing cancer cells |
AU760669B2 (en) * | 1998-04-28 | 2003-05-22 | Galenica Pharmaceuticals, Inc. | Polysaccharide-antigen conjugates |
US20030091546A1 (en) * | 1998-11-12 | 2003-05-15 | Barber Jack R. | Methods of suppressing immune response by gene therapy |
AU6921300A (en) * | 1999-08-20 | 2001-03-19 | Sloan-Kettering Institute For Cancer Research | Novel glycoconjugates, glycoamino, acids, intermediates thereto, and uses thereof |
US7854934B2 (en) * | 1999-08-20 | 2010-12-21 | Sloan-Kettering Institute For Cancer Research | Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof |
US7824687B2 (en) | 1999-08-20 | 2010-11-02 | Sloan-Kettering Institute For Cancer Research | Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof |
DE10005275A1 (de) * | 2000-02-07 | 2001-08-09 | Bayer Ag | Neuartige Glycokonjugate |
US20030049253A1 (en) * | 2001-08-08 | 2003-03-13 | Li Frank Q. | Polymeric conjugates for delivery of MHC-recognized epitopes via peptide vaccines |
UA79952C2 (en) * | 2001-12-10 | 2007-08-10 | Kabulesh Mafatlal Khamar | MYCOBACTERIUM w APPLICATIONS FOR CANCER TREATMENT |
EP1594898A2 (de) * | 2003-02-06 | 2005-11-16 | Tripep AB | Glycosylierte spezifitätaustauscher |
WO2005077411A2 (en) * | 2004-02-10 | 2005-08-25 | Innate Pharma | Composition and method for the treatment of carcinoma |
BRPI0611535B1 (pt) | 2005-05-05 | 2021-11-30 | Sensient Flavors Inc | Método para processar células de levedura para produzir beta-glucanos e mananas |
CA2634034A1 (en) | 2005-12-20 | 2007-06-28 | Duke University | Methods and compositions for delivering active agents with enhanced pharmacological properties |
US9249187B2 (en) | 2009-01-28 | 2016-02-02 | Epimmune Inc. | Pan-DR binding polypeptides and uses thereof |
MX362513B (es) | 2010-03-23 | 2019-01-22 | Intrexon Corp | Vectores que expresan de manera condicional proteinas terapeuticas, celulas hospedadoras que comprenden vectores, y usos de los mismos. |
EP2500033A1 (de) | 2011-03-17 | 2012-09-19 | Institut Pasteur | Verfahren zur Herstellung mehrfacher Antigen-Glycopeptid-Kohlenhydratkonjugate |
KR102436439B1 (ko) | 2011-06-28 | 2022-08-25 | 이노비오 파마수티컬즈, 인크. | 최소 침습 피부 전기천공 장치 |
EP2606897A1 (de) * | 2011-12-22 | 2013-06-26 | Laboratorios Del. Dr. Esteve, S.A. | Verfahren und Zusammensetzungen für die Behandlung von Krankheiten, die von eingehüllten Viren verursacht werden |
WO2019014456A1 (en) * | 2017-07-12 | 2019-01-17 | The Board Of Trustees Of The Leland Stanford Junior University | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCERS HAVING A MUTATION H3K27M |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2004744B (en) * | 1977-09-28 | 1982-05-26 | Sanderson A R | Immonulogical preparations |
CA1335883C (en) * | 1986-07-08 | 1995-06-13 | Bryan Michael Longenecker | Enhancement of the cellular immune response |
EP0399001B1 (de) * | 1988-02-01 | 1994-07-27 | Praxis Biologics, Inc. | T-zellen-epitope als träger für einen konjugierten impfstoff |
WO1989007448A1 (en) * | 1988-02-12 | 1989-08-24 | Regents Of The University Of California | Use of synthetic peptides to generate and manipulate cellular immunity |
US5229289A (en) * | 1988-03-11 | 1993-07-20 | The Biomembrane Institute | Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with animal and human and with synthetic carbohydrate-carrier conjugates |
CA1337403C (en) * | 1988-03-28 | 1995-10-24 | Biomembrane Institute (The) | Methods for the production of antibodies and induction of immune responses to tumor-associated gangliosides by immunization with ganglioside lactones |
JPH04506662A (ja) * | 1989-07-14 | 1992-11-19 | アメリカン・サイアナミド・カンパニー | 接合体ワクチンのためのサイトカイニンおよびホルモンのキヤリヤー |
AU6272190A (en) * | 1989-08-28 | 1991-04-08 | Pierce Chemical Company | Cationized carriers for immunogen production |
GB8924438D0 (en) * | 1989-10-31 | 1989-12-20 | Hoffmann La Roche | Vaccine composition |
IT1237764B (it) * | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
-
1993
- 1993-04-22 IL IL10550393A patent/IL105503A/en not_active IP Right Cessation
- 1993-04-23 AU AU42746/93A patent/AU676679B2/en not_active Ceased
- 1993-04-23 DK DK93912042T patent/DK0675733T3/da active
- 1993-04-23 ES ES93912042T patent/ES2155070T3/es not_active Expired - Lifetime
- 1993-04-23 AT AT93912042T patent/ATE197903T1/de not_active IP Right Cessation
- 1993-04-23 EP EP93912042A patent/EP0675733B1/de not_active Expired - Lifetime
- 1993-04-23 PT PT93912042T patent/PT675733E/pt unknown
- 1993-04-23 JP JP5519172A patent/JPH07506358A/ja not_active Abandoned
- 1993-04-23 WO PCT/SE1993/000353 patent/WO1993021948A1/en active IP Right Grant
- 1993-04-23 DE DE69329735T patent/DE69329735T2/de not_active Expired - Fee Related
- 1993-04-23 CA CA002134097A patent/CA2134097A1/en not_active Abandoned
- 1993-04-27 MA MA23178A patent/MA22885A1/fr unknown
- 1993-04-27 US US08/054,860 patent/US5807559A/en not_active Expired - Fee Related
- 1993-04-27 IS IS4010A patent/IS4010A/is unknown
- 1993-04-28 MY MYPI93000788A patent/MY108864A/en unknown
- 1993-04-28 CN CN93106340A patent/CN1096032A/zh active Pending
- 1993-04-28 TN TNTNSN93045A patent/TNSN93045A1/fr unknown
- 1993-04-28 SI SI9300223A patent/SI9300223A/sl unknown
-
1995
- 1995-05-16 US US08/442,378 patent/US6033669A/en not_active Expired - Fee Related
-
2001
- 2001-03-05 GR GR20010400341T patent/GR3035501T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69329735T2 (de) | 2001-08-02 |
IS4010A (is) | 1993-10-29 |
CN1096032A (zh) | 1994-12-07 |
DK0675733T3 (da) | 2001-05-07 |
SI9300223A (en) | 1994-03-31 |
PT675733E (pt) | 2001-05-31 |
JPH07506358A (ja) | 1995-07-13 |
EP0675733A1 (de) | 1995-10-11 |
EP0675733B1 (de) | 2000-12-06 |
AU676679B2 (en) | 1997-03-20 |
DE69329735D1 (de) | 2001-01-11 |
TNSN93045A1 (fr) | 1994-03-17 |
MA22885A1 (fr) | 1993-12-31 |
AU4274693A (en) | 1993-11-29 |
IL105503A0 (en) | 1993-08-18 |
CA2134097A1 (en) | 1993-11-11 |
US6033669A (en) | 2000-03-07 |
WO1993021948A1 (en) | 1993-11-11 |
US5807559A (en) | 1998-09-15 |
IL105503A (en) | 1999-05-09 |
MY108864A (en) | 1996-11-30 |
ES2155070T3 (es) | 2001-05-01 |
GR3035501T3 (en) | 2001-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
EEIH | Change in the person of patent owner | ||
REN | Ceased due to non-payment of the annual fee |