ATE197671T1 - Pharmazeutische stabile nicorandil-formulierungen - Google Patents

Pharmazeutische stabile nicorandil-formulierungen

Info

Publication number
ATE197671T1
ATE197671T1 AT93304427T AT93304427T ATE197671T1 AT E197671 T1 ATE197671 T1 AT E197671T1 AT 93304427 T AT93304427 T AT 93304427T AT 93304427 T AT93304427 T AT 93304427T AT E197671 T1 ATE197671 T1 AT E197671T1
Authority
AT
Austria
Prior art keywords
formulations
nicorandil
composition
pharmaceutical stable
stable nicorandil
Prior art date
Application number
AT93304427T
Other languages
English (en)
Inventor
Paolo Alberto Veronesi
Anna Maria Veronesi
Original Assignee
Therapicon Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therapicon Srl filed Critical Therapicon Srl
Application granted granted Critical
Publication of ATE197671T1 publication Critical patent/ATE197671T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT93304427T 1992-06-08 1993-06-08 Pharmazeutische stabile nicorandil-formulierungen ATE197671T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI921413A IT1256022B (it) 1992-06-08 1992-06-08 Preparazioni farmaceutiche stabili di nicorandil

Publications (1)

Publication Number Publication Date
ATE197671T1 true ATE197671T1 (de) 2000-12-15

Family

ID=11363474

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93304427T ATE197671T1 (de) 1992-06-08 1993-06-08 Pharmazeutische stabile nicorandil-formulierungen

Country Status (10)

Country Link
US (1) US5580576A (de)
EP (1) EP0574221B1 (de)
JP (1) JP2893307B2 (de)
KR (1) KR100196212B1 (de)
AT (1) ATE197671T1 (de)
DE (1) DE69329691T2 (de)
ES (1) ES2153835T3 (de)
IT (1) IT1256022B (de)
MX (1) MX9303165A (de)
PT (1) PT574221E (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6129673A (en) * 1998-06-08 2000-10-10 Advanced Monitors, Corp. Infrared thermometer
JP4472035B2 (ja) * 1998-06-17 2010-06-02 森下仁丹株式会社 長期保存安定性に優れたカプセル製剤
US20040151785A1 (en) * 1998-10-06 2004-08-05 Diamedica Inc. Method for treating insulin resistance through hepatic nitric oxide
AU3810100A (en) * 1999-03-12 2000-10-04 Basf Aktiengesellschaft Stable pharmaceutical application form for paroxetin anhydrate
US6417207B1 (en) 1999-05-12 2002-07-09 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
US20090035260A1 (en) * 2002-07-29 2009-02-05 Therapicon Srl Enhanced nasal composition of active peptide
FR2850275B1 (fr) * 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
DE10328260A1 (de) * 2003-06-23 2005-01-27 Schmidt, K.-G., Dr. med. Flupirtine-Präparat
US8153161B2 (en) 2003-12-09 2012-04-10 Dainippon Sumitomo Pharma Co., Ltd. Medicament-containing particle and a solid preparation containing the particle
ITMI20040235A1 (it) * 2004-02-13 2004-05-13 Therapicon Srl Preparazione farmaceutica per il cavo orale
US20070281008A1 (en) * 2006-06-05 2007-12-06 Lin Shun Y Personal lubricant compositions and kits for providing personal lubrication
WO2012144943A1 (en) * 2011-04-18 2012-10-26 Lipidor Ab Liquid carrier for oral delivery of a pharmacologically active agent
US20130315891A1 (en) 2012-05-25 2013-11-28 Matthew Charles Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
EP2854841B1 (de) 2012-06-04 2017-02-22 Diamedica Inc. Kallikrein-1-glycosylierungsisoformen aus menschlichem gewebe
CN110446501A (zh) 2017-03-09 2019-11-12 代阿麦迪卡股份有限公司 组织激肽释放酶1的剂型
CN110123749B (zh) * 2019-06-03 2022-01-25 太阳升(亳州)生物医药科技有限公司 尼可地尔脂微球制剂及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986006960A2 (en) * 1985-05-22 1986-12-04 Beecham Group P.L.C. Use of nicorandil or pinacidil for the treatment of peripheral vascular disease
US5188840A (en) * 1985-09-26 1993-02-23 Chugai Seiyaku Kabushiki Kaisha Slow-release pharmaceutical agent
JPS6351326A (ja) * 1986-08-22 1988-03-04 Nisshin Flour Milling Co Ltd ニコランジル外用剤
US5057317A (en) * 1987-03-24 1991-10-15 Chugai Seiyaku Kabushiki Kaisha Slow-release pharmaceutical agent
US4837029A (en) * 1987-04-06 1989-06-06 Carolina Medical Products, Inc. Low foaming, aqueously homogenizable rifampin composition
FR2624012B1 (fr) * 1987-12-07 1991-05-31 Fdb Ste Civile Rech Nouvelles compositions pharmaceutiques a action hypnotique a base d'hydrate de chloral
US5112604A (en) * 1989-09-01 1992-05-12 Riker Laboratories, Inc. Oral suspension formulation

Also Published As

Publication number Publication date
EP0574221B1 (de) 2000-11-22
PT574221E (pt) 2001-04-30
DE69329691T2 (de) 2001-05-10
JP2893307B2 (ja) 1999-05-17
DE69329691D1 (de) 2000-12-28
KR100196212B1 (ko) 1999-06-15
ITMI921413A0 (it) 1992-06-08
EP0574221A1 (de) 1993-12-15
KR940000104A (ko) 1994-01-03
JPH0640916A (ja) 1994-02-15
MX9303165A (es) 1993-12-31
ES2153835T3 (es) 2001-03-16
ITMI921413A1 (it) 1993-12-08
US5580576A (en) 1996-12-03
IT1256022B (it) 1995-11-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee