ATE19241T1 - 4-aminomethyl-5-acyl-1,3-dihydro-imidazol-2-one - Google Patents

4-aminomethyl-5-acyl-1,3-dihydro-imidazol-2-one

Info

Publication number
ATE19241T1
ATE19241T1 AT82103739T AT82103739T ATE19241T1 AT E19241 T1 ATE19241 T1 AT E19241T1 AT 82103739 T AT82103739 T AT 82103739T AT 82103739 T AT82103739 T AT 82103739T AT E19241 T1 ATE19241 T1 AT E19241T1
Authority
AT
Austria
Prior art keywords
dihydro
acyl
aminomethyl
imidazole
imidazol
Prior art date
Application number
AT82103739T
Other languages
English (en)
Inventor
Martin J Grisar
Richard C Dage
Richard A Schnettler
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of ATE19241T1 publication Critical patent/ATE19241T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70One oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cardiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
AT82103739T 1981-05-04 1982-05-03 4-aminomethyl-5-acyl-1,3-dihydro-imidazol-2-one ATE19241T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/260,446 US4381393A (en) 1981-05-04 1981-05-04 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
EP82103739A EP0064704B1 (de) 1981-05-04 1982-05-03 4-Aminomethyl-5-acyl-1,3-dihydro-imidazol-2-one

Publications (1)

Publication Number Publication Date
ATE19241T1 true ATE19241T1 (de) 1986-05-15

Family

ID=22989196

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82103739T ATE19241T1 (de) 1981-05-04 1982-05-03 4-aminomethyl-5-acyl-1,3-dihydro-imidazol-2-one

Country Status (10)

Country Link
US (1) US4381393A (de)
EP (1) EP0064704B1 (de)
JP (1) JPS57185265A (de)
AT (1) ATE19241T1 (de)
AU (1) AU546890B2 (de)
CA (1) CA1175828A (de)
DE (1) DE3270566D1 (de)
ES (1) ES511870A0 (de)
IL (1) IL65666A (de)
ZA (1) ZA822989B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62122845A (ja) * 1985-11-25 1987-06-04 Pioneer Electronic Corp 車載用テレビ装置
ZA887662B (en) * 1987-10-19 1989-06-28 Merrell Dow Pharma Method for reducing reperfusion injury with imidazol-2-thione-carboxamides
IT1230703B (it) * 1989-01-26 1991-10-29 Luso Farmaco Inst Derivati imidazolonici ad attivita' antiipertensiva, loro metodi di preparazione e composizioni farmaceutiche che li contengono.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them
US2441935A (en) * 1946-03-14 1948-05-18 Hoffmann La Roche Imidazolidones and method for their manufacture
US2514380A (en) * 1946-12-26 1950-07-11 Hoffmann La Roche Diamines and method of production
US3303199A (en) * 1963-07-15 1967-02-07 Geigy Chem Corp Certain imidazolone derivatives and process for making same
IL24005A (en) * 1964-12-31 1970-05-21 Robins Co Inc A H 1,3-disubstituted-4-(2-substituted-ethyl)-2-imidazolidinones,processes for their production and pharmaceutical compositions containing them
NZ193935A (en) * 1979-06-18 1985-05-31 Richardson Merrell Inc 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions

Also Published As

Publication number Publication date
IL65666A (en) 1985-12-31
EP0064704B1 (de) 1986-04-16
AU546890B2 (en) 1985-09-26
ES8308875A1 (es) 1983-10-01
EP0064704A1 (de) 1982-11-17
DE3270566D1 (de) 1986-05-22
US4381393A (en) 1983-04-26
CA1175828A (en) 1984-10-09
AU8317882A (en) 1982-11-11
IL65666A0 (en) 1982-08-31
JPS57185265A (en) 1982-11-15
ES511870A0 (es) 1983-10-01
ZA822989B (en) 1983-03-30
JPH024219B2 (de) 1990-01-26

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee