DE3270566D1 - 4-aminomethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones - Google Patents

4-aminomethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones

Info

Publication number
DE3270566D1
DE3270566D1 DE8282103739T DE3270566T DE3270566D1 DE 3270566 D1 DE3270566 D1 DE 3270566D1 DE 8282103739 T DE8282103739 T DE 8282103739T DE 3270566 T DE3270566 T DE 3270566T DE 3270566 D1 DE3270566 D1 DE 3270566D1
Authority
DE
Germany
Prior art keywords
imidazol
dihydro
acyl
ones
aminomethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282103739T
Other languages
English (en)
Inventor
Martin J Grisar
Richard C Dage
Richard A Schnettler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of DE3270566D1 publication Critical patent/DE3270566D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Diabetes (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
DE8282103739T 1981-05-04 1982-05-03 4-aminomethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones Expired DE3270566D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/260,446 US4381393A (en) 1981-05-04 1981-05-04 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones

Publications (1)

Publication Number Publication Date
DE3270566D1 true DE3270566D1 (de) 1986-05-22

Family

ID=22989196

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282103739T Expired DE3270566D1 (de) 1981-05-04 1982-05-03 4-aminomethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones

Country Status (10)

Country Link
US (1) US4381393A (de)
EP (1) EP0064704B1 (de)
JP (1) JPS57185265A (de)
AT (1) ATE19241T1 (de)
AU (1) AU546890B2 (de)
CA (1) CA1175828A (de)
DE (1) DE3270566D1 (de)
ES (1) ES8308875A1 (de)
IL (1) IL65666A (de)
ZA (1) ZA822989B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62122845A (ja) * 1985-11-25 1987-06-04 Pioneer Electronic Corp 車載用テレビ装置
ZA887662B (en) * 1987-10-19 1989-06-28 Merrell Dow Pharma Method for reducing reperfusion injury with imidazol-2-thione-carboxamides
IT1230703B (it) * 1989-01-26 1991-10-29 Luso Farmaco Inst Derivati imidazolonici ad attivita' antiipertensiva, loro metodi di preparazione e composizioni farmaceutiche che li contengono.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them
US2441935A (en) * 1946-03-14 1948-05-18 Hoffmann La Roche Imidazolidones and method for their manufacture
US2514380A (en) * 1946-12-26 1950-07-11 Hoffmann La Roche Diamines and method of production
US3303199A (en) * 1963-07-15 1967-02-07 Geigy Chem Corp Certain imidazolone derivatives and process for making same
IL24005A (en) * 1964-12-31 1970-05-21 Robins Co Inc A H 1,3-disubstituted-4-(2-substituted-ethyl)-2-imidazolidinones,processes for their production and pharmaceutical compositions containing them
NZ193935A (en) * 1979-06-18 1985-05-31 Richardson Merrell Inc 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions

Also Published As

Publication number Publication date
EP0064704B1 (de) 1986-04-16
AU8317882A (en) 1982-11-11
IL65666A0 (en) 1982-08-31
ATE19241T1 (de) 1986-05-15
EP0064704A1 (de) 1982-11-17
JPH024219B2 (de) 1990-01-26
CA1175828A (en) 1984-10-09
IL65666A (en) 1985-12-31
JPS57185265A (en) 1982-11-15
ZA822989B (en) 1983-03-30
US4381393A (en) 1983-04-26
AU546890B2 (en) 1985-09-26
ES511870A0 (es) 1983-10-01
ES8308875A1 (es) 1983-10-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee