ATE189207T1 - Bistriazene als chemotherapeutische wirkstoffe - Google Patents

Bistriazene als chemotherapeutische wirkstoffe

Info

Publication number
ATE189207T1
ATE189207T1 AT92923053T AT92923053T ATE189207T1 AT E189207 T1 ATE189207 T1 AT E189207T1 AT 92923053 T AT92923053 T AT 92923053T AT 92923053 T AT92923053 T AT 92923053T AT E189207 T1 ATE189207 T1 AT E189207T1
Authority
AT
Austria
Prior art keywords
compounds
bistriazene
cancer
bistriazenes
chemotherapeutic agents
Prior art date
Application number
AT92923053T
Other languages
English (en)
Inventor
Christopher J Michejda
Jeffrey J Blumenstein
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of ATE189207T1 publication Critical patent/ATE189207T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/76Nitrogen atoms to which a second hetero atom is attached
    • C07D213/77Hydrazine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/22Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond containing chains of three or more nitrogen atoms with one or more nitrogen-to-nitrogen double bonds
    • C07C245/24Chains of only three nitrogen atoms, e.g. diazoamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
AT92923053T 1991-10-31 1992-10-30 Bistriazene als chemotherapeutische wirkstoffe ATE189207T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78600191A 1991-10-31 1991-10-31
PCT/US1992/009127 WO1993009089A1 (en) 1991-10-31 1992-10-30 Bistriazenes as chemotherapeutic agents

Publications (1)

Publication Number Publication Date
ATE189207T1 true ATE189207T1 (de) 2000-02-15

Family

ID=25137306

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92923053T ATE189207T1 (de) 1991-10-31 1992-10-30 Bistriazene als chemotherapeutische wirkstoffe

Country Status (10)

Country Link
EP (1) EP0626943B1 (de)
JP (1) JP3193379B2 (de)
AT (1) ATE189207T1 (de)
AU (1) AU665036B2 (de)
CA (1) CA2122346C (de)
DE (1) DE69230622T2 (de)
DK (1) DK0626943T3 (de)
ES (1) ES2141114T3 (de)
GR (1) GR3032953T3 (de)
WO (1) WO1993009089A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE513149C2 (sv) * 1997-12-05 2000-07-17 Katarina Edwards Läkemedelsdistributionssystem med tvåstegsmålsökning, till specifika celler eller vävnad och till dess cellkärna
WO2020121304A1 (en) * 2018-12-10 2020-06-18 Ariel Scientific Innovations Ltd. Therapeutic conjugates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE514033A (fr) * 1951-09-21 1954-05-14 Cfmc Procede d'obtention de colorants azoiques insolubles sur fibres.
US3947247A (en) * 1973-10-31 1976-03-30 Central Michigan University Board Of Trustees Stabilizer composition for dyestuffs
DE3426644A1 (de) * 1984-07-19 1986-02-06 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts, 6900 Heidelberg N,n-bis((1-aryl-3-methyltriazen-3-yl) methyl)ether
DE69131481T2 (de) * 1990-05-24 1999-11-25 The United States Of America, Represented By The Secretary Bistriazene als chemotherapeutische mittel

Also Published As

Publication number Publication date
CA2122346C (en) 2005-09-27
GR3032953T3 (en) 2000-07-31
JPH07507042A (ja) 1995-08-03
EP0626943B1 (de) 2000-01-26
CA2122346A1 (en) 1993-05-13
JP3193379B2 (ja) 2001-07-30
AU665036B2 (en) 1995-12-14
ES2141114T3 (es) 2000-03-16
EP0626943A1 (de) 1994-12-07
DE69230622D1 (de) 2000-03-02
WO1993009089A1 (en) 1993-05-13
DE69230622T2 (de) 2000-07-20
AU2910392A (en) 1993-06-07
DK0626943T3 (da) 2000-04-17

Similar Documents

Publication Publication Date Title
BR9100016A (pt) Composto,isotopo radioativo do mesmo,composicao farmaceutica,metodo de tratamento ou prevencao de estados de mamiferos
FI980341A0 (fi) 2-oksi-indolijohdannaisia
ATE7697T1 (de) Substituierte pyrazinyl-1,2,4-oxadiazol-5-one, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung.
ATE182468T1 (de) Bistriazene als chemotherapeutische mittel
YU13396A (sh) N-(3-benzofuranil) urea derivati, postupci za njihovo dobijanje, kompozicije koje ih sadrže i njihova upotreba u lekovima
ES2133324T3 (es) Compuestos de dibenzoxazepina sustituidos, composiciones farmaceuticas y metodos de uso.
DE68902301D1 (de) Diarylverbindungen als antiatherosklerotische mittel.
DE59203006D1 (de) Amidinophenylalaninderivate, Verfahren zu deren Herstellung, deren Verwendung und diese enthaltende Mittel.
KR960703863A (ko) 암 치료용 신규 비스-나프탈이미드(New Bis-naphthalimides for the Treatment of Cancer)
ATE41772T1 (de) Polymethoxybenzyl-piperazin-derivate, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen.
GR75683B (de)
ATE189207T1 (de) Bistriazene als chemotherapeutische wirkstoffe
BR9106272A (pt) Composicoes farmaceuticas contendo ipriflavona,processo para sua preparacao e uso terapeutico relativo
ATE220393T1 (de) Eine heteroethynylen-brücke enthaltende bi- aromatische verbindungen und diese enthaltende pharmazeutische und kosmetische zusammensetzungen
DE3370157D1 (en) Derivatives of tricyclophosphazenes, process for their preparation and their use as medicines
NZ233704A (en) Dehydrocholecalciferol derivatives, pharmaceutical compositions thereof
ITMI920084A1 (it) Alchil derivati del trazodone
DE58903821D1 (de) Verwendung von addukten von 1,2-butylenoxid an aminen als schmierstoffe und schmierstoffe, diese addukte enthaltend.
DE69311123D1 (de) Cyclische benzylamino-, benzylamido- und benzylimido derivate als antipsychotische wirkstoffe
SE8200649L (sv) Polycykliska foreningar innehallande en dubbelbindning i d-ringen, sett for deras framstellning och farmaceutiska beredningar innehallande dem
ATE118763T1 (de) Phenolisches amin als antimelanoma- und depigmentierungsmittel.
KR890017363A (ko) 스트로빌루린 유도체, 이들의 제법 및 용도
NO903291D0 (no) Renin-hemmende aminooligohydroksy-derivater.
SE7708452L (sv) Komposition innehallande en antrakinonforening
ATE41774T1 (de) (+)-cyanidan-3-ol derivate, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee