ATE187643T1 - Verringerung von knochenschwund durch antiöstrogen-kombinationen - Google Patents

Verringerung von knochenschwund durch antiöstrogen-kombinationen

Info

Publication number
ATE187643T1
ATE187643T1 AT96303874T AT96303874T ATE187643T1 AT E187643 T1 ATE187643 T1 AT E187643T1 AT 96303874 T AT96303874 T AT 96303874T AT 96303874 T AT96303874 T AT 96303874T AT E187643 T1 ATE187643 T1 AT E187643T1
Authority
AT
Austria
Prior art keywords
antestrogen
combinations
bone loss
reducing bone
reducing
Prior art date
Application number
AT96303874T
Other languages
English (en)
Inventor
George Joseph Cullinan
Steven Anthony Fontana
Robin Sharon Lee Fuchs-Young
Andrew Lawrence Glasebrook
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE187643T1 publication Critical patent/ATE187643T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT96303874T 1995-06-06 1996-05-30 Verringerung von knochenschwund durch antiöstrogen-kombinationen ATE187643T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47111195A 1995-06-06 1995-06-06

Publications (1)

Publication Number Publication Date
ATE187643T1 true ATE187643T1 (de) 2000-01-15

Family

ID=23870302

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96303874T ATE187643T1 (de) 1995-06-06 1996-05-30 Verringerung von knochenschwund durch antiöstrogen-kombinationen

Country Status (27)

Country Link
EP (1) EP0747056B1 (de)
JP (1) JP2001501907A (de)
KR (1) KR19990022497A (de)
CN (1) CN1239429A (de)
AR (2) AR003002A1 (de)
AT (1) ATE187643T1 (de)
AU (1) AU696927B2 (de)
BR (1) BR9608390A (de)
CA (1) CA2223174A1 (de)
CO (1) CO4700447A1 (de)
CZ (1) CZ383097A3 (de)
DE (1) DE69605600T2 (de)
DK (1) DK0747056T3 (de)
EA (1) EA199800014A1 (de)
ES (1) ES2142545T3 (de)
GR (1) GR3032863T3 (de)
HU (1) HUP9900854A3 (de)
IL (1) IL118573A (de)
NO (1) NO975560L (de)
PE (1) PE2298A1 (de)
PL (1) PL323941A1 (de)
PT (1) PT747056E (de)
SI (1) SI0747056T1 (de)
TR (1) TR199701508T1 (de)
WO (1) WO1996039141A1 (de)
YU (1) YU34296A (de)
ZA (1) ZA964681B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159696A (en) * 1996-11-22 2000-12-12 Akzo Nobel N.V. Isolated human BMP-4 promoter region
GB2324726A (en) * 1997-05-01 1998-11-04 Merck & Co Inc Combination Therapy for the Treatment of Osteoporosis
US6096764A (en) * 1997-08-21 2000-08-01 Eli Lilly And Company Methods for inhibiting detrimental side-effects due to GnRH of GnRH agonist administration
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4895715A (en) * 1988-04-14 1990-01-23 Schering Corporation Method of treating gynecomastia
US5393785A (en) * 1988-10-31 1995-02-28 Endorecherche, Inc. Therapeutic antiestrogens
US5482949A (en) * 1993-03-19 1996-01-09 Eli Lilly And Company Sulfonate derivatives of 3-aroylbenzo[b]thiophenes
DE4329344A1 (de) * 1993-08-27 1995-03-02 Schering Ag Progesteronantagonistisch- und antiöstrogen wirksame Verbindungen für die Behandlung des Leiomyomata uteri

Also Published As

Publication number Publication date
AR003134A1 (es) 1998-07-08
SI0747056T1 (en) 2000-06-30
TR199701508T1 (xx) 1998-03-21
KR19990022497A (ko) 1999-03-25
DK0747056T3 (da) 2000-05-01
CZ383097A3 (cs) 1998-09-16
JP2001501907A (ja) 2001-02-13
EP0747056A3 (de) 1997-03-05
CA2223174A1 (en) 1996-12-12
NO975560D0 (no) 1997-12-02
BR9608390A (pt) 1999-05-04
DE69605600T2 (de) 2000-05-31
AR003002A1 (es) 1998-05-27
AU5981696A (en) 1996-12-24
AU696927B2 (en) 1998-09-24
HUP9900854A2 (hu) 1999-08-30
EP0747056B1 (de) 1999-12-15
PE2298A1 (es) 1998-02-28
GR3032863T3 (en) 2000-07-31
CO4700447A1 (es) 1998-12-29
YU34296A (en) 1999-11-22
DE69605600D1 (de) 2000-01-20
PT747056E (pt) 2000-05-31
EP0747056A2 (de) 1996-12-11
IL118573A0 (en) 1996-10-16
ES2142545T3 (es) 2000-04-16
WO1996039141A1 (en) 1996-12-12
HUP9900854A3 (en) 2000-03-28
CN1239429A (zh) 1999-12-22
PL323941A1 (en) 1998-04-27
NO975560L (no) 1998-01-26
EA199800014A1 (ru) 1998-06-25
ZA964681B (en) 1997-12-05
IL118573A (en) 2000-01-31

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee