ATE187643T1 - Verringerung von knochenschwund durch antiöstrogen-kombinationen - Google Patents

Verringerung von knochenschwund durch antiöstrogen-kombinationen

Info

Publication number
ATE187643T1
ATE187643T1 AT96303874T AT96303874T ATE187643T1 AT E187643 T1 ATE187643 T1 AT E187643T1 AT 96303874 T AT96303874 T AT 96303874T AT 96303874 T AT96303874 T AT 96303874T AT E187643 T1 ATE187643 T1 AT E187643T1
Authority
AT
Austria
Prior art keywords
antestrogen
combinations
bone loss
reducing bone
reducing
Prior art date
Application number
AT96303874T
Other languages
English (en)
Inventor
George Joseph Cullinan
Steven Anthony Fontana
Robin Sharon Lee Fuchs-Young
Andrew Lawrence Glasebrook
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE187643T1 publication Critical patent/ATE187643T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT96303874T 1995-06-06 1996-05-30 Verringerung von knochenschwund durch antiöstrogen-kombinationen ATE187643T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47111195A 1995-06-06 1995-06-06

Publications (1)

Publication Number Publication Date
ATE187643T1 true ATE187643T1 (de) 2000-01-15

Family

ID=23870302

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96303874T ATE187643T1 (de) 1995-06-06 1996-05-30 Verringerung von knochenschwund durch antiöstrogen-kombinationen

Country Status (27)

Country Link
EP (1) EP0747056B1 (de)
JP (1) JP2001501907A (de)
KR (1) KR19990022497A (de)
CN (1) CN1239429A (de)
AR (2) AR003134A1 (de)
AT (1) ATE187643T1 (de)
AU (1) AU696927B2 (de)
BR (1) BR9608390A (de)
CA (1) CA2223174A1 (de)
CO (1) CO4700447A1 (de)
CZ (1) CZ383097A3 (de)
DE (1) DE69605600T2 (de)
DK (1) DK0747056T3 (de)
EA (1) EA199800014A1 (de)
ES (1) ES2142545T3 (de)
GR (1) GR3032863T3 (de)
HU (1) HUP9900854A3 (de)
IL (1) IL118573A (de)
NO (1) NO975560L (de)
PE (1) PE2298A1 (de)
PL (1) PL323941A1 (de)
PT (1) PT747056E (de)
SI (1) SI0747056T1 (de)
TR (1) TR199701508T1 (de)
WO (1) WO1996039141A1 (de)
YU (1) YU34296A (de)
ZA (1) ZA964681B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2272345A1 (en) * 1996-11-22 1998-06-04 Akzo Nobel Nv Bmp-4 promoter and use thereof in screening of therapeutic agents for the prevention and/or treatment of osteoporosis
GB2324726A (en) * 1997-05-01 1998-11-04 Merck & Co Inc Combination Therapy for the Treatment of Osteoporosis
US6096764A (en) * 1997-08-21 2000-08-01 Eli Lilly And Company Methods for inhibiting detrimental side-effects due to GnRH of GnRH agonist administration
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6465445B1 (en) * 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4895715A (en) * 1988-04-14 1990-01-23 Schering Corporation Method of treating gynecomastia
US5393785A (en) * 1988-10-31 1995-02-28 Endorecherche, Inc. Therapeutic antiestrogens
US5482949A (en) * 1993-03-19 1996-01-09 Eli Lilly And Company Sulfonate derivatives of 3-aroylbenzo[b]thiophenes
DE4329344A1 (de) * 1993-08-27 1995-03-02 Schering Ag Progesteronantagonistisch- und antiöstrogen wirksame Verbindungen für die Behandlung des Leiomyomata uteri

Also Published As

Publication number Publication date
EP0747056A3 (de) 1997-03-05
HUP9900854A3 (en) 2000-03-28
AU696927B2 (en) 1998-09-24
YU34296A (en) 1999-11-22
CN1239429A (zh) 1999-12-22
IL118573A (en) 2000-01-31
KR19990022497A (ko) 1999-03-25
PT747056E (pt) 2000-05-31
ZA964681B (en) 1997-12-05
TR199701508T1 (xx) 1998-03-21
BR9608390A (pt) 1999-05-04
NO975560D0 (no) 1997-12-02
AU5981696A (en) 1996-12-24
AR003134A1 (es) 1998-07-08
NO975560L (no) 1998-01-26
HUP9900854A2 (hu) 1999-08-30
EP0747056B1 (de) 1999-12-15
DE69605600T2 (de) 2000-05-31
DK0747056T3 (da) 2000-05-01
IL118573A0 (en) 1996-10-16
WO1996039141A1 (en) 1996-12-12
CZ383097A3 (cs) 1998-09-16
GR3032863T3 (en) 2000-07-31
PE2298A1 (es) 1998-02-28
CO4700447A1 (es) 1998-12-29
SI0747056T1 (en) 2000-06-30
EP0747056A2 (de) 1996-12-11
PL323941A1 (en) 1998-04-27
AR003002A1 (es) 1998-05-27
EA199800014A1 (ru) 1998-06-25
DE69605600D1 (de) 2000-01-20
ES2142545T3 (es) 2000-04-16
CA2223174A1 (en) 1996-12-12
JP2001501907A (ja) 2001-02-13

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee