ATE175195T1 - Naphthamide, verfahren zur herstellung und ihre therapeutische anwendung - Google Patents
Naphthamide, verfahren zur herstellung und ihre therapeutische anwendungInfo
- Publication number
- ATE175195T1 ATE175195T1 AT92402862T AT92402862T ATE175195T1 AT E175195 T1 ATE175195 T1 AT E175195T1 AT 92402862 T AT92402862 T AT 92402862T AT 92402862 T AT92402862 T AT 92402862T AT E175195 T1 ATE175195 T1 AT E175195T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- aminoethyl
- new
- naphthamide
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/66—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems and singly-bound oxygen atoms, bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9113103A FR2682953B1 (fr) | 1991-10-23 | 1991-10-23 | Nouveaux derives de naphtamides, leur procede de preparation et leur application dans le domaine therapeutique. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE175195T1 true ATE175195T1 (de) | 1999-01-15 |
Family
ID=9418243
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92402862T ATE175195T1 (de) | 1991-10-23 | 1992-10-20 | Naphthamide, verfahren zur herstellung und ihre therapeutische anwendung |
Country Status (10)
Country | Link |
---|---|
US (1) | US5498628A (de) |
EP (1) | EP0539281B1 (de) |
JP (1) | JPH05331135A (de) |
AT (1) | ATE175195T1 (de) |
CA (1) | CA2081147A1 (de) |
DE (1) | DE69228042T2 (de) |
DK (1) | DK0539281T3 (de) |
ES (1) | ES2125886T3 (de) |
FR (1) | FR2682953B1 (de) |
GR (1) | GR3029703T3 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9320855D0 (en) * | 1993-10-09 | 1993-12-01 | Smithkline Beecham Plc | Compounds |
GB9402197D0 (en) * | 1994-02-04 | 1994-03-30 | Smithkline Beecham Plc | Compounds |
GB9403199D0 (en) * | 1994-02-19 | 1994-04-13 | Smithkline Beecham Plc | Compounds |
US5395835A (en) * | 1994-03-24 | 1995-03-07 | Warner-Lambert Company | Naphthalamides as central nervous system agents |
DE4425146A1 (de) * | 1994-07-15 | 1996-01-18 | Basf Ag | Verwendung heterocyclischer Verbindungen |
FR2738569B1 (fr) * | 1995-09-12 | 1997-11-28 | Pf Medicament | Nouveaux derives naphtamide de 3 beta-amino azabicyclo octane ou nonane, leur procede de preparation, leur utilisation a titre de medicament antipsychotique |
US5659033A (en) * | 1995-09-13 | 1997-08-19 | Neurogen Corporation | N-aminoalkylfluorenecarboxamides; a new class of dopamine receptor subtype specific ligands |
FR2742149B1 (fr) * | 1995-12-11 | 1998-02-13 | Inst Nat Sante Rech Med | Nouveaux derives de 2-naphtamides et leurs applications therapeutiques |
US5703235A (en) | 1996-03-21 | 1997-12-30 | Neurogen Corporation | N-Aminoalkyl-2-anthracenecarboxamides; new dopamine receptor subtype specific ligands |
CN105792824B (zh) * | 2013-12-13 | 2018-08-03 | 皮埃尔法布雷医药公司 | 色酮衍生物作为多巴胺d3受体拮抗剂用于治疗自闭症谱系障碍的用途 |
US20180305334A1 (en) * | 2015-10-14 | 2018-10-25 | Aquinnah Pharmaceuticals, Inc. | Compounds, compositions and methods of use against stress granules |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3615605A (en) * | 1967-03-22 | 1971-10-26 | Konishiroku Photo Ind | Light-sensitive silver halide color-photographic material containing naphthal color couplers |
GB1248766A (en) * | 1967-09-13 | 1971-10-06 | Scott Graphics | Light-sensitive diazo compositions |
US4540814A (en) * | 1983-06-24 | 1985-09-10 | Adria Laboratories, Inc. | 1,4-Dimethoxy naphthalenecarboxamide anticonvulsants |
SE8503055D0 (sv) * | 1985-06-19 | 1985-06-19 | Astra Laekemedel Ab | Piperonylcarboxamido derivatives |
US5122361A (en) * | 1989-04-17 | 1992-06-16 | Trustees Of The University Of Pennsylvania | Dopamine receptor ligands and imaging agents |
-
1991
- 1991-10-23 FR FR9113103A patent/FR2682953B1/fr not_active Expired - Fee Related
-
1992
- 1992-10-20 ES ES92402862T patent/ES2125886T3/es not_active Expired - Lifetime
- 1992-10-20 DE DE69228042T patent/DE69228042T2/de not_active Expired - Fee Related
- 1992-10-20 DK DK92402862T patent/DK0539281T3/da active
- 1992-10-20 AT AT92402862T patent/ATE175195T1/de not_active IP Right Cessation
- 1992-10-20 EP EP92402862A patent/EP0539281B1/de not_active Expired - Lifetime
- 1992-10-22 CA CA002081147A patent/CA2081147A1/en not_active Abandoned
- 1992-10-23 US US07/965,927 patent/US5498628A/en not_active Expired - Lifetime
- 1992-10-23 JP JP4309548A patent/JPH05331135A/ja not_active Withdrawn
-
1999
- 1999-03-16 GR GR990400787T patent/GR3029703T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0539281B1 (de) | 1998-12-30 |
EP0539281A1 (de) | 1993-04-28 |
FR2682953B1 (fr) | 1995-04-21 |
DE69228042T2 (de) | 1999-05-27 |
ES2125886T3 (es) | 1999-03-16 |
GR3029703T3 (en) | 1999-06-30 |
DK0539281T3 (da) | 1999-08-30 |
CA2081147A1 (en) | 1993-04-24 |
FR2682953A1 (fr) | 1993-04-30 |
DE69228042D1 (de) | 1999-02-11 |
US5498628A (en) | 1996-03-12 |
JPH05331135A (ja) | 1993-12-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |