ATE169002T1 - Polyamidsäure-derivate mit antigastrin wirkung, ihre herstellung und ihre verwendung als arzneimittel - Google Patents
Polyamidsäure-derivate mit antigastrin wirkung, ihre herstellung und ihre verwendung als arzneimittelInfo
- Publication number
- ATE169002T1 ATE169002T1 AT94927576T AT94927576T ATE169002T1 AT E169002 T1 ATE169002 T1 AT E169002T1 AT 94927576 T AT94927576 T AT 94927576T AT 94927576 T AT94927576 T AT 94927576T AT E169002 T1 ATE169002 T1 AT E169002T1
- Authority
- AT
- Austria
- Prior art keywords
- antigastrin
- production
- effect
- acid derivatives
- pct
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITTO930661A IT1261255B (it) | 1993-09-09 | 1993-09-09 | Derivati acidi poliamidici ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE169002T1 true ATE169002T1 (de) | 1998-08-15 |
Family
ID=11411721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94927576T ATE169002T1 (de) | 1993-09-09 | 1994-09-07 | Polyamidsäure-derivate mit antigastrin wirkung, ihre herstellung und ihre verwendung als arzneimittel |
Country Status (9)
Country | Link |
---|---|
US (1) | US5962502A (de) |
EP (1) | EP0717732B1 (de) |
JP (1) | JPH09502433A (de) |
AT (1) | ATE169002T1 (de) |
CA (1) | CA2170648A1 (de) |
DE (1) | DE69412103T2 (de) |
ES (1) | ES2123827T3 (de) |
IT (1) | IT1261255B (de) |
WO (1) | WO1995007261A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1276462B1 (it) * | 1995-07-03 | 1997-10-31 | Rotta Research Lab | Diamidi aromatiche acide ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico |
WO1997044341A1 (en) * | 1996-05-17 | 1997-11-27 | Rotta Research Laboratorium S.P.A. | Cyclic polyamides of glutamic acid and aspartic acid with anti-gastrin activity, a method for their preparation and their pharmaceutical use |
WO1997045415A1 (en) * | 1996-05-28 | 1997-12-04 | Rotta Research Laboratorium S.P.A. | Polyamide derivatives or ornithine, lysine and analogous substances with cck-b and gastrin-antagonistic activity |
ES2202625T3 (es) * | 1996-06-13 | 2004-04-01 | Novartis Ag | Peptidos. |
IT1286141B1 (it) * | 1996-07-02 | 1998-07-07 | Rotta Research Lab | Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico. |
CA2791174C (en) | 2010-03-04 | 2015-11-17 | Ajinomoto Co., Inc. | Alkylamine derivative |
JP6502939B2 (ja) | 2013-11-22 | 2019-04-17 | シーエル バイオサイエンシズ リミティド ライアビリティ カンパニー | 骨粗鬆症の処置及び予防のためのガストリン拮抗薬 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1241029B (it) * | 1990-12-11 | 1993-12-27 | Rotta Research Lab | Derivati amidici biciclici e policiclici degli acidi glutammico, aspartico e 2-ammino adipico ad attivita' antigastrinica e procedimento per la loro preparazione |
IT1263116B (it) * | 1992-04-09 | 1996-07-30 | Rotta Research Lab | Derivati basici dell'acido glutammico ed acido aspartico, procedimento per la loro preparazione e loro uso farmaceutico |
-
1993
- 1993-09-09 IT ITTO930661A patent/IT1261255B/it active IP Right Grant
-
1994
- 1994-09-07 EP EP94927576A patent/EP0717732B1/de not_active Expired - Lifetime
- 1994-09-07 ES ES94927576T patent/ES2123827T3/es not_active Expired - Lifetime
- 1994-09-07 JP JP7508456A patent/JPH09502433A/ja active Pending
- 1994-09-07 DE DE69412103T patent/DE69412103T2/de not_active Expired - Fee Related
- 1994-09-07 US US08/605,162 patent/US5962502A/en not_active Expired - Fee Related
- 1994-09-07 CA CA002170648A patent/CA2170648A1/en not_active Abandoned
- 1994-09-07 WO PCT/EP1994/002983 patent/WO1995007261A1/en active IP Right Grant
- 1994-09-07 AT AT94927576T patent/ATE169002T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US5962502A (en) | 1999-10-05 |
ITTO930661A1 (it) | 1995-03-09 |
ITTO930661A0 (it) | 1993-09-09 |
WO1995007261A1 (en) | 1995-03-16 |
IT1261255B (it) | 1996-05-09 |
DE69412103D1 (de) | 1998-09-03 |
DE69412103T2 (de) | 1999-04-22 |
CA2170648A1 (en) | 1995-03-16 |
ES2123827T3 (es) | 1999-01-16 |
EP0717732A1 (de) | 1996-06-26 |
JPH09502433A (ja) | 1997-03-11 |
EP0717732B1 (de) | 1998-07-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |