ATE165354T1 - Lactone mit antioxidativer und hypolipidaemischer wirkung zur behandlung von atherosklerose - Google Patents

Lactone mit antioxidativer und hypolipidaemischer wirkung zur behandlung von atherosklerose

Info

Publication number
ATE165354T1
ATE165354T1 AT95118629T AT95118629T ATE165354T1 AT E165354 T1 ATE165354 T1 AT E165354T1 AT 95118629 T AT95118629 T AT 95118629T AT 95118629 T AT95118629 T AT 95118629T AT E165354 T1 ATE165354 T1 AT E165354T1
Authority
AT
Austria
Prior art keywords
atherosclerosis
lactones
treatment
antioxidant
lipoproteins
Prior art date
Application number
AT95118629T
Other languages
English (en)
Inventor
Goffredo Rosini
Claudia Baldazzi
Eleonora Romagnoli
Stefano Saguatti
Silvano Piani
Original Assignee
Alfa Wassermann Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Wassermann Spa filed Critical Alfa Wassermann Spa
Application granted granted Critical
Publication of ATE165354T1 publication Critical patent/ATE165354T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
AT95118629T 1994-12-21 1995-11-27 Lactone mit antioxidativer und hypolipidaemischer wirkung zur behandlung von atherosklerose ATE165354T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITBO940562A IT1274355B (it) 1994-12-21 1994-12-21 Lattoni ad attivita' antiossidante ed ipolipidemica utili nella terapia dell'aterosclerosi

Publications (1)

Publication Number Publication Date
ATE165354T1 true ATE165354T1 (de) 1998-05-15

Family

ID=11340165

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95118629T ATE165354T1 (de) 1994-12-21 1995-11-27 Lactone mit antioxidativer und hypolipidaemischer wirkung zur behandlung von atherosklerose

Country Status (9)

Country Link
US (1) US5608084A (de)
EP (1) EP0718295B1 (de)
JP (1) JP2820652B2 (de)
AT (1) ATE165354T1 (de)
DE (1) DE69502168T2 (de)
DK (1) DK0718295T3 (de)
ES (1) ES2115308T3 (de)
GR (1) GR3026702T3 (de)
IT (1) IT1274355B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002015845A2 (en) * 2000-08-21 2002-02-28 Merck & Co., Inc. Anti-hypercholesterolemic drug combination
DE10261067A1 (de) * 2002-12-24 2004-08-05 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Cholesterinsenkendes Mittel, enthaltend eine n-3-Fettsäure

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674836A (en) * 1968-05-21 1972-07-04 Parke Davis & Co 2,2-dimethyl-{11 -aryloxy-alkanoic acids and salts and esters thereof
US4665091A (en) * 1985-11-04 1987-05-12 Merck & Co., Inc. Macrocyclic lactone HMG-CoA reductase inhibitors
US5196447A (en) * 1991-08-08 1993-03-23 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting On Behalf Of Arizona State University Neristatin 1

Also Published As

Publication number Publication date
DE69502168T2 (de) 1998-08-13
JPH08231535A (ja) 1996-09-10
ITBO940562A1 (it) 1996-06-21
US5608084A (en) 1997-03-04
JP2820652B2 (ja) 1998-11-05
IT1274355B (it) 1997-07-17
ES2115308T3 (es) 1998-06-16
GR3026702T3 (en) 1998-07-31
EP0718295B1 (de) 1998-04-22
ITBO940562A0 (it) 1994-12-21
DK0718295T3 (da) 1999-01-11
DE69502168D1 (de) 1998-05-28
EP0718295A1 (de) 1996-06-26

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee