ATE164161T1 - Antiparasitäre makrolid-antibiotika - Google Patents

Antiparasitäre makrolid-antibiotika

Info

Publication number
ATE164161T1
ATE164161T1 AT89301564T AT89301564T ATE164161T1 AT E164161 T1 ATE164161 T1 AT E164161T1 AT 89301564 T AT89301564 T AT 89301564T AT 89301564 T AT89301564 T AT 89301564T AT E164161 T1 ATE164161 T1 AT E164161T1
Authority
AT
Austria
Prior art keywords
macrolide antibiotics
antiparasitic
antibiotics
antiparasitic macrolide
acari
Prior art date
Application number
AT89301564T
Other languages
English (en)
Inventor
David Austen Dr Perry
Mark Andrew Dr Haxell
Hiroshi Maeda
Junsuke Tone
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Application granted granted Critical
Publication of ATE164161T1 publication Critical patent/ATE164161T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/445—The saccharide radical is condensed with a heterocyclic radical, e.g. everninomycin, papulacandin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/55—Streptomyces hygroscopicus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y10S435/898—Streptomyces hygroscopicus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Biomedical Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT89301564T 1988-02-25 1989-02-17 Antiparasitäre makrolid-antibiotika ATE164161T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888804440A GB8804440D0 (en) 1988-02-25 1988-02-25 Antiparasitic agents

Publications (1)

Publication Number Publication Date
ATE164161T1 true ATE164161T1 (de) 1998-04-15

Family

ID=10632372

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89301564T ATE164161T1 (de) 1988-02-25 1989-02-17 Antiparasitäre makrolid-antibiotika

Country Status (10)

Country Link
US (3) US5510372A (de)
EP (1) EP0334484B1 (de)
JP (1) JPH0699437B2 (de)
AT (1) ATE164161T1 (de)
CA (1) CA1339965C (de)
DE (1) DE68928606T2 (de)
DK (1) DK169738B1 (de)
ES (1) ES2113340T3 (de)
GB (1) GB8804440D0 (de)
PT (1) PT89806B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8721371D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
WO1999017760A2 (en) 1997-10-02 1999-04-15 Microcide Pharmaceuticals, Inc. Fungal or mammalian cell efflux pump inhibitors for enhancing susceptibility of the cell to a drug
GB9807180D0 (en) 1998-04-04 1998-06-03 Ecc Int Ltd Pigment products
GB9825402D0 (en) 1998-11-19 1999-01-13 Pfizer Ltd Antiparasitic formulations
CA2368750C (en) 1999-04-01 2010-09-28 Imerys Pigments, Inc. Kaolin clay pigments, their preparation and use
AU759343B2 (en) 1999-04-01 2003-04-10 Imerys Pigments, Inc. Kaolin pigments, their preparation and use
US6554892B1 (en) 1999-07-02 2003-04-29 Imerys Kaolin, Inc. Compositions and methods for making a coarse platey, high brightness kaolin product
GB0020180D0 (en) 2000-08-17 2000-10-04 Imerys Minerals Ltd Kaolin products and their production
GB0020179D0 (en) 2000-08-17 2000-10-04 Imerys Minerals Ltd Kaolin products and their use
GB0020182D0 (en) 2000-08-17 2000-10-04 Imerys Minerals Ltd Particulate kaolin
US20030085012A1 (en) 2001-09-07 2003-05-08 Jones J Philip E Hyperplaty clays and their use in paper coating and filling, methods for making same, and paper products having improved brightness
CZ2004378A3 (cs) 2001-09-17 2004-07-14 Eli Lilly And Company Název neuveden
US6808559B2 (en) 2002-02-26 2004-10-26 Imerys Pigments, Inc. Kaolin clay pigments suited to rotogravure printing applications and method for preparing the same
WO2003082965A1 (en) * 2002-03-28 2003-10-09 Imerys Minerals Limited Flame retardant polymer compositions comprising a particulate clay mineral
EP2327410A1 (de) 2009-10-28 2011-06-01 Consiglio Nazionale Delle Ricerche - Infm Istituto Nazionale Per La Fisica Della Materia Avermectine und Milbemycine zur Behandlung von Flavivirus Infektionen
CN113956212B (zh) * 2021-10-29 2024-04-30 西南大学 具有抗线虫活性的thermolides类化合物及其制备方法和应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950360A (en) * 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
JPS4914624A (de) * 1972-06-08 1974-02-08
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
US4412991A (en) * 1981-08-28 1983-11-01 Merck & Co., Inc. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
DE3519834C2 (de) * 1984-06-05 1993-12-16 American Cyanamid Co Neue antibiotische Wirkstoffe, Verfahren zu ihrer Gewinnung und ihre Anwendung zur Bekämpfung von Infektionen bei Tieren und Pflanzen
BE903232A (fr) * 1984-09-14 1986-03-13 Glaxo Group Ltd Composes antibiotiques et leur procede de preparation
AU574852B2 (en) * 1984-10-26 1988-07-14 Sankyo Company Limited 13 - acyloxy - 5 - ketomilbemycin derivatives and preparation of 13 - hydroxy - 5 - ketomilbemycin derivatives
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
US4857509A (en) * 1985-01-22 1989-08-15 Ciba-Geigy Corporation 13β-alkylmilbemycin derivatives for controlling parasites of animals and plants
US4666937A (en) * 1985-03-04 1987-05-19 Merck & Co., Inc. Avermectin bioconversion products
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
NZ215917A (en) * 1985-05-02 1989-10-27 Merck & Co Inc 22-oh milbemycin derivatives and parasiticidal compositions
NZ219576A (en) * 1986-03-12 1989-01-06 Glaxo Group Ltd Milbemycin derivatives and pharmaceutical, veterinary, and pesticidal compositions
JPS631007A (ja) * 1986-06-20 1988-01-06 Nec Corp 電磁リレ−
EP0253378A3 (de) * 1986-07-18 1988-03-23 Ciba-Geigy Ag 13Beta-Alkyl-derivate von S541-Antibiotika zur Bekämpfung von Parasiten an Nutztieren und Pflanzen
JP2587241B2 (ja) * 1986-07-24 1997-03-05 ビ−チヤム・グル−プ・ピ−エルシ− 新規化合物、その製法及びそれを含む医薬組成物
JP2504501B2 (ja) * 1987-01-09 1996-06-05 三共株式会社 新規マクロライド化合物およびその製造法
ES2053797T3 (es) * 1987-02-04 1994-08-01 Ciba Geigy Ag Procedimiento microbiano para la obtencion de derivados de milbemicina.
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
GB8709327D0 (en) * 1987-04-21 1987-05-28 Beecham Group Plc Compounds
EP0325462A3 (de) * 1988-01-22 1989-11-02 Beecham Group Plc Milbemycin-Derivate mit anthelmintischer Wirkung

Also Published As

Publication number Publication date
US5589366A (en) 1996-12-31
EP0334484A2 (de) 1989-09-27
CA1339965C (en) 1998-07-21
DK86589D0 (da) 1989-02-24
DK86589A (da) 1989-08-28
DK169738B1 (da) 1995-02-06
PT89806B (pt) 1994-04-29
JPH0699437B2 (ja) 1994-12-07
EP0334484B1 (de) 1998-03-18
ES2113340T3 (es) 1998-05-01
DE68928606D1 (de) 1998-04-23
EP0334484A3 (de) 1991-05-29
DE68928606T2 (de) 1998-07-02
PT89806A (pt) 1989-10-04
US5573946A (en) 1996-11-12
US5510372A (en) 1996-04-23
GB8804440D0 (en) 1988-03-23
JPH01272588A (ja) 1989-10-31

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee