ATE163200T1 - Verfahren zur herstellung von peptiden mit c- terminalem prolin-amid - Google Patents
Verfahren zur herstellung von peptiden mit c- terminalem prolin-amidInfo
- Publication number
- ATE163200T1 ATE163200T1 AT93303756T AT93303756T ATE163200T1 AT E163200 T1 ATE163200 T1 AT E163200T1 AT 93303756 T AT93303756 T AT 93303756T AT 93303756 T AT93303756 T AT 93303756T AT E163200 T1 ATE163200 T1 AT E163200T1
- Authority
- AT
- Austria
- Prior art keywords
- terminal proline
- proline amide
- producing peptides
- carboxypeptidase
- terminal
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- VLJNHYLEOZPXFW-BYPYZUCNSA-N L-prolinamide Chemical group NC(=O)[C@@H]1CCCN1 VLJNHYLEOZPXFW-BYPYZUCNSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 102000005572 Cathepsin A Human genes 0.000 abstract 2
- 108010059081 Cathepsin A Proteins 0.000 abstract 2
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 125000001500 prolyl group Chemical group [H]N1C([H])(C(=O)[*])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/003—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by transforming the C-terminal amino acid to amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57527—Calcitonin gene related peptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12095992 | 1992-05-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE163200T1 true ATE163200T1 (de) | 1998-02-15 |
Family
ID=14799232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93303756T ATE163200T1 (de) | 1992-05-14 | 1993-05-14 | Verfahren zur herstellung von peptiden mit c- terminalem prolin-amid |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0570244B1 (de) |
| JP (1) | JP3187201B2 (de) |
| AT (1) | ATE163200T1 (de) |
| CA (1) | CA2096180A1 (de) |
| DE (1) | DE69316936T2 (de) |
| DK (1) | DK0570244T3 (de) |
| ES (1) | ES2114004T3 (de) |
| GR (1) | GR3026431T3 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016258837B2 (en) * | 2015-05-01 | 2020-12-03 | Onl Therapeutics, Inc. | Peptide compositions and methods of use |
| US12319945B2 (en) | 2018-12-18 | 2025-06-03 | Patheon Austria Gmbh & Co Kg | Single step biocatalytic amidation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6229997A (ja) * | 1985-04-08 | 1987-02-07 | Sankyo Co Ltd | Ｃ末端にプロリンアミドを有するペプチドの製法 |
-
1993
- 1993-05-11 JP JP10898893A patent/JP3187201B2/ja not_active Expired - Fee Related
- 1993-05-13 CA CA002096180A patent/CA2096180A1/en not_active Abandoned
- 1993-05-14 ES ES93303756T patent/ES2114004T3/es not_active Expired - Lifetime
- 1993-05-14 EP EP93303756A patent/EP0570244B1/de not_active Expired - Lifetime
- 1993-05-14 AT AT93303756T patent/ATE163200T1/de not_active IP Right Cessation
- 1993-05-14 DE DE69316936T patent/DE69316936T2/de not_active Expired - Fee Related
- 1993-05-14 DK DK93303756T patent/DK0570244T3/da active
-
1998
- 1998-03-20 GR GR980400621T patent/GR3026431T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0570244A1 (de) | 1993-11-18 |
| GR3026431T3 (en) | 1998-06-30 |
| JPH0690779A (ja) | 1994-04-05 |
| HK1003839A1 (en) | 1998-11-06 |
| EP0570244B1 (de) | 1998-02-11 |
| DK0570244T3 (da) | 1998-09-23 |
| JP3187201B2 (ja) | 2001-07-11 |
| DE69316936D1 (de) | 1998-03-19 |
| ES2114004T3 (es) | 1998-05-16 |
| DE69316936T2 (de) | 1998-09-17 |
| CA2096180A1 (en) | 1993-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |