ATE157870T1 - Ophthalmische zusammensetzung enthaltend ein 1,5- benzoxathiepin-derivat zur behandlung von glaukoma - Google Patents
Ophthalmische zusammensetzung enthaltend ein 1,5- benzoxathiepin-derivat zur behandlung von glaukomaInfo
- Publication number
- ATE157870T1 ATE157870T1 AT95100934T AT95100934T ATE157870T1 AT E157870 T1 ATE157870 T1 AT E157870T1 AT 95100934 T AT95100934 T AT 95100934T AT 95100934 T AT95100934 T AT 95100934T AT E157870 T1 ATE157870 T1 AT E157870T1
- Authority
- AT
- Austria
- Prior art keywords
- optionally substituted
- hydrogen
- treatment
- ophthalmic composition
- benzoxathiepine
- Prior art date
Links
- 208000010412 Glaucoma Diseases 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 208000030533 eye disease Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 125000005346 substituted cycloalkyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP747094 | 1994-01-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE157870T1 true ATE157870T1 (de) | 1997-09-15 |
Family
ID=11666688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95100934T ATE157870T1 (de) | 1994-01-27 | 1995-01-25 | Ophthalmische zusammensetzung enthaltend ein 1,5- benzoxathiepin-derivat zur behandlung von glaukoma |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5538974A (enExample) |
| EP (1) | EP0667156B1 (enExample) |
| KR (1) | KR950032169A (enExample) |
| CN (1) | CN1116928A (enExample) |
| AT (1) | ATE157870T1 (enExample) |
| CA (1) | CA2141176A1 (enExample) |
| DE (1) | DE69500660T2 (enExample) |
| ES (1) | ES2106573T3 (enExample) |
| TW (1) | TW316235B (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6960579B1 (en) | 1998-05-19 | 2005-11-01 | Alcon Manufacturing, Ltd. | Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders |
| TR200100754T2 (tr) | 1998-09-18 | 2001-10-22 | Alcon Laboratories, Inc. | Glausomanın tedavi edilmesi için serotonerjik 5HT2. |
| CA2397203A1 (en) * | 2000-03-31 | 2001-10-11 | Sandra C. Tobias | Phosphoramidate prodrugs |
| FR2822467B1 (fr) * | 2001-03-22 | 2003-12-12 | Pf Medicament | Derives benzoxathiepines et leur utilisation comme medicaments |
| JP2005511764A (ja) * | 2001-12-14 | 2005-04-28 | アルコン，インコーポレイテッド | 緑内障の処置のためのアミノアルキルベンゾフラン−５−オール化合物 |
| TW593302B (en) * | 2001-12-20 | 2004-06-21 | Alcon Inc | Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma |
| WO2004009586A1 (en) * | 2002-07-19 | 2004-01-29 | Biovitrum Ab | Novel piperazinyl-pyrazinone derivatives for the treatment of 5-ht2a receptor-related disorders |
| WO2004019874A2 (en) * | 2002-08-30 | 2004-03-11 | Alcon, Inc. | Substituted 5-chroman-5-yl-ethylamine compounds and their use for the treatment of glaucoma |
| EP1581209A4 (en) * | 2002-12-13 | 2009-03-11 | Alcon Inc | NEW BENZOPYRAN ANALOGUE AND ITS USE FOR THE TREATMENT OF GLAUKOM |
| TWI347847B (en) * | 2003-08-20 | 2011-09-01 | Santen Pharmaceutical Co Ltd | Drug delivery system for sub-tenon administration of fine particles |
| WO2005053688A1 (en) * | 2003-11-26 | 2005-06-16 | Alcon, Inc. | Substituted furo[2,3-g] indazoles for the treatment of glaucoma |
| US7129257B1 (en) | 2003-12-15 | 2006-10-31 | Alcon, Inc. | Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma |
| WO2005058911A2 (en) * | 2003-12-15 | 2005-06-30 | Alcon, Inc. | Substituted [1,4]oxazino[2,3-g]indazoles for the treatment of glaucoma |
| US7338972B1 (en) | 2003-12-15 | 2008-03-04 | Alcon, Inc. | Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma |
| US20050276867A1 (en) * | 2004-06-09 | 2005-12-15 | Allergan, Inc. | Stabilized compositions comprising a therapeutically active agent and an oxidizing preservative |
| US7425572B2 (en) * | 2004-12-08 | 2008-09-16 | Alcon, Inc. | Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma |
| TW200744567A (en) * | 2005-09-23 | 2007-12-16 | Alcon Inc | Phenylethylamine analogs and their use for treating glaucoma |
| WO2007149728A2 (en) * | 2006-06-20 | 2007-12-27 | Alcon Research, Ltd. | Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma |
| EA200900583A1 (ru) * | 2006-10-20 | 2009-08-28 | Общество С Ограниченной Ответственностью "Митотехнология" | Композиция для регенерации, стимуляции роста и адаптации растений к различным стрессовым факторам |
| EA200900582A1 (ru) * | 2006-10-20 | 2009-08-28 | Общество С Ограниченной Ответственностью "Митотехнология" | Фармацевтические композиции для профилактики и лечения глазных патологий |
| US8349902B2 (en) * | 2007-01-29 | 2013-01-08 | Mitotech Sa | Pharmaceutical compositions useful for preventing and treating oncological diseases |
| US9427444B2 (en) * | 2007-01-29 | 2016-08-30 | Mitotech Sa | Pharmaceutical and cosmetic compositions for accelerated healing of wounds and other surface damages |
| EA016723B1 (ru) * | 2007-02-27 | 2012-07-30 | Дели Инститьют Оф Фармасьютикал Сайнсиз Энд Рисерч (Дипсар) | Синергетическая травяная композиция, применяемая при глаукоме, и способ ее получения |
| US9439916B2 (en) * | 2007-04-11 | 2016-09-13 | Mitotech Sa | Composition for decelerating the aging in the organism and for extending the life time thereof and the use of said composition |
| US8518915B2 (en) | 2007-06-29 | 2013-08-27 | Mitotech Sa | Use of mitochondrially-addressed compounds for preventing and treating cardiovascular diseases |
| WO2010056145A1 (ru) | 2008-11-12 | 2010-05-20 | Общество С Ограниченной Ответственностью "Митотехнология" | Способ умеренного повышения протонной проводимости биологических мембран при помощи митохондриально- адресованных делокализованных катионов |
| JP5659388B2 (ja) * | 2009-06-10 | 2015-01-28 | マイトテック ソシエテ アノニム | 医学及び獣医眼科の使用のための医薬組成物 |
| CN102791670A (zh) | 2009-11-13 | 2012-11-21 | 米拓科技有限责任公司 | 基于定向于线粒体的抗氧化剂的药物物质 |
| JP2013545800A (ja) | 2010-12-20 | 2013-12-26 | コルゲート・パーモリブ・カンパニー | 親水性活性剤、疎水性構造化剤および油担体を含有するゼラチンカプセル化された口腔ケア組成物 |
| CN103764132B (zh) | 2011-06-03 | 2017-04-12 | 米托特克公司 | 线粒体靶向的抗氧化剂的口服制剂及其制备和用途 |
| CN114767688A (zh) * | 2019-09-04 | 2022-07-22 | 武汉科福新药有限责任公司 | 透皮促渗组合物及其在噻吗洛尔制剂中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK166779B1 (da) * | 1983-12-14 | 1993-07-12 | Takeda Chemical Industries Ltd | 1,5-benzoxatiepinderivater eller farmaceutisk acceptable salte deraf, samt farmaceutisk praeparat indeholdende en saadan forbindelse |
| EP0229467A1 (en) * | 1985-12-10 | 1987-07-22 | Takeda Chemical Industries, Ltd. | 1,5-Benzoxathiepin derivatives, their production and use |
-
1995
- 1995-01-24 US US08/378,244 patent/US5538974A/en not_active Expired - Fee Related
- 1995-01-25 DE DE69500660T patent/DE69500660T2/de not_active Expired - Fee Related
- 1995-01-25 EP EP95100934A patent/EP0667156B1/en not_active Expired - Lifetime
- 1995-01-25 TW TW084100643A patent/TW316235B/zh active
- 1995-01-25 ES ES95100934T patent/ES2106573T3/es not_active Expired - Lifetime
- 1995-01-25 AT AT95100934T patent/ATE157870T1/de not_active IP Right Cessation
- 1995-01-26 CA CA002141176A patent/CA2141176A1/en not_active Abandoned
- 1995-01-27 CN CN95100372A patent/CN1116928A/zh active Pending
- 1995-01-27 KR KR1019950001542A patent/KR950032169A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP0667156A1 (en) | 1995-08-16 |
| DE69500660T2 (de) | 1998-02-26 |
| CA2141176A1 (en) | 1995-07-28 |
| CN1116928A (zh) | 1996-02-21 |
| KR950032169A (ko) | 1995-12-20 |
| ES2106573T3 (es) | 1997-11-01 |
| TW316235B (enExample) | 1997-09-21 |
| DE69500660D1 (de) | 1997-10-16 |
| EP0667156B1 (en) | 1997-09-10 |
| US5538974A (en) | 1996-07-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |