ATE151078T1 - Verfahren und zwischenprodukte synthetischer antikörperderivate - Google Patents
Verfahren und zwischenprodukte synthetischer antikörperderivateInfo
- Publication number
- ATE151078T1 ATE151078T1 AT91908713T AT91908713T ATE151078T1 AT E151078 T1 ATE151078 T1 AT E151078T1 AT 91908713 T AT91908713 T AT 91908713T AT 91908713 T AT91908713 T AT 91908713T AT E151078 T1 ATE151078 T1 AT E151078T1
- Authority
- AT
- Austria
- Prior art keywords
- intermediates
- intermediate products
- synthetic antibodies
- chimeric antibodies
- antibody derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/809—Drug, bio-affecting and body treating compositions involving immunoglobulin or antibody fragment, e.g. fab', fv, fc, heavy chain or light chain
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909009106A GB9009106D0 (en) | 1990-04-23 | 1990-04-23 | Processes and intermediates for synthetic antibody derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE151078T1 true ATE151078T1 (de) | 1997-04-15 |
Family
ID=10674863
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT91908713T ATE151078T1 (de) | 1990-04-23 | 1991-04-22 | Verfahren und zwischenprodukte synthetischer antikörperderivate |
Country Status (7)
Country | Link |
---|---|
US (1) | US6136313A (de) |
EP (1) | EP0528856B1 (de) |
JP (1) | JPH05507268A (de) |
AT (1) | ATE151078T1 (de) |
DE (1) | DE69125485T2 (de) |
GB (1) | GB9009106D0 (de) |
WO (1) | WO1991016354A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995032734A1 (en) * | 1994-05-26 | 1995-12-07 | Innogenetics N.V. | New methods and compounds for the selective modulation of antigen-specific t-cell responsiveness |
US20030133939A1 (en) | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
US20030157091A1 (en) * | 2002-02-14 | 2003-08-21 | Dyax Corporation | Multi-functional proteins |
TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
ES2558102T3 (es) | 2003-05-06 | 2016-02-02 | Biogen Hemophilia Inc. | Proteínas quiméricas del factor de coagulación para el tratamiento de un trastorno hemostático |
US7700097B2 (en) * | 2003-06-27 | 2010-04-20 | Biogen Idec Ma Inc. | Purification and preferential synthesis of binding molecules |
US8110665B2 (en) | 2003-11-13 | 2012-02-07 | Hanmi Holdings Co., Ltd. | Pharmaceutical composition comprising an immunoglobulin FC region as a carrier |
JP4870569B2 (ja) | 2003-11-13 | 2012-02-08 | ハンミ ホールディングス カンパニー リミテッド | 免疫グロブリン断片を用いた蛋白質結合体およびその製造方法 |
ZA200604864B (en) * | 2003-12-19 | 2007-10-31 | Genentech Inc | Monovalent antibody fragments useful as therapeutics |
US20070014789A1 (en) * | 2005-07-15 | 2007-01-18 | Bayer Healthcare Llc | Humanized antibody conjugates and related methods, assays, reagents, and kits |
RS54088B1 (en) | 2005-07-25 | 2015-10-30 | Emergent Products Development Seattle Llc | B-CELL REDUCTION BY USING CD37-SPECIFIC AND CD20-SPECIFIC BINDING MOLECULES |
WO2007086994A1 (en) * | 2005-11-15 | 2007-08-02 | Balyasnikova Irina V | Single chain fragment of monoclonal antibody 9b9 and uses thereof |
US20080108147A1 (en) * | 2006-11-03 | 2008-05-08 | Tie Wei | Reduction of non-specific binding in immunoassays |
US20090252729A1 (en) * | 2007-05-14 | 2009-10-08 | Farrington Graham K | Single-chain Fc (scFc) regions, binding polypeptides comprising same, and methods related thereto |
NZ588671A (en) | 2008-04-11 | 2012-11-30 | Emergent Product Dev Seattle | Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof |
EP2968498A4 (de) | 2013-03-15 | 2016-09-07 | Biogen Ma Inc | Faktor-ix-polypeptidformulierungen |
CA2999138C (en) | 2015-09-21 | 2024-05-21 | Aptevo Research And Development Llc | Cd3 binding polypeptides |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2556219B1 (fr) * | 1983-12-07 | 1987-06-26 | Merieux Inst | Nouveau medicament immunomodulateur, a base de fragments fc d'igg humaines |
GB8824869D0 (en) * | 1988-10-24 | 1988-11-30 | Stevenson G T | Synthetic antibody |
FR2639231A1 (fr) * | 1988-11-23 | 1990-05-25 | Merieux Inst | Utilisation de fragments fc d'immunoglobulines g humaines, de peptides analogues du fragment fc, ou d'immunoglobulines g humaines dans l'obtention d'un medicament preparatoire a l'administration chez l'homme, dans un but therapeutique ou de diagnostic, d'anticorps monoclonaux |
-
1990
- 1990-04-23 GB GB909009106A patent/GB9009106D0/en active Pending
-
1991
- 1991-04-22 EP EP91908713A patent/EP0528856B1/de not_active Expired - Lifetime
- 1991-04-22 WO PCT/GB1991/000633 patent/WO1991016354A1/en active IP Right Grant
- 1991-04-22 JP JP91508209A patent/JPH05507268A/ja active Pending
- 1991-04-22 DE DE69125485T patent/DE69125485T2/de not_active Expired - Fee Related
- 1991-04-22 AT AT91908713T patent/ATE151078T1/de active
-
1995
- 1995-03-13 US US08/403,520 patent/US6136313A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6136313A (en) | 2000-10-24 |
DE69125485D1 (de) | 1997-05-07 |
JPH05507268A (ja) | 1993-10-21 |
GB9009106D0 (en) | 1990-06-20 |
EP0528856B1 (de) | 1997-04-02 |
WO1991016354A1 (en) | 1991-10-31 |
EP0528856A1 (de) | 1993-03-03 |
DE69125485T2 (de) | 1997-07-24 |
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