ATE150297T1 - Oberflaechenmodifizierte nsaid nanopartikeln - Google Patents

Oberflaechenmodifizierte nsaid nanopartikeln

Info

Publication number
ATE150297T1
ATE150297T1 AT93914224T AT93914224T ATE150297T1 AT E150297 T1 ATE150297 T1 AT E150297T1 AT 93914224 T AT93914224 T AT 93914224T AT 93914224 T AT93914224 T AT 93914224T AT E150297 T1 ATE150297 T1 AT E150297T1
Authority
AT
Austria
Prior art keywords
surface modified
modified nsaid
nsaid nanoparticles
nanoparticles
maintain
Prior art date
Application number
AT93914224T
Other languages
English (en)
Inventor
Gary G Liversidge
Philip Conzentino
Kenneth Cundy
Pramod P Sarpotdar
Original Assignee
Nanosystems Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25407503&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE150297(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nanosystems Llc filed Critical Nanosystems Llc
Application granted granted Critical
Publication of ATE150297T1 publication Critical patent/ATE150297T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
AT93914224T 1992-06-10 1993-06-01 Oberflaechenmodifizierte nsaid nanopartikeln ATE150297T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89719392A 1992-06-10 1992-06-10

Publications (1)

Publication Number Publication Date
ATE150297T1 true ATE150297T1 (de) 1997-04-15

Family

ID=25407503

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93914224T ATE150297T1 (de) 1992-06-10 1993-06-01 Oberflaechenmodifizierte nsaid nanopartikeln

Country Status (12)

Country Link
EP (1) EP0644755B1 (de)
JP (2) JP4439590B2 (de)
AT (1) ATE150297T1 (de)
AU (1) AU677783B2 (de)
CA (1) CA2118517C (de)
DE (1) DE69309056T2 (de)
DK (1) DK0644755T3 (de)
ES (1) ES2101323T3 (de)
GR (1) GR3022880T3 (de)
HU (1) HUT70952A (de)
MX (1) MX9303452A (de)
WO (1) WO1993025190A1 (de)

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US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
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US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
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US9101540B2 (en) 2002-04-12 2015-08-11 Alkermes Pharma Ireland Limited Nanoparticulate megestrol formulations
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ES2365012T3 (es) * 2002-11-12 2011-09-20 Elan Pharma International Limited Formas farmacéuticas sólidas de desintegración rápida que no son friables y que comprenden pululano.
EP1938803A3 (de) * 2003-03-03 2010-10-27 Elan Pharma International Limited Formulierungen mit Nanoteilchen-Meloxican
US20100297252A1 (en) 2003-03-03 2010-11-25 Elan Pharma International Ltd. Nanoparticulate meloxicam formulations
US8512727B2 (en) * 2003-03-03 2013-08-20 Alkermes Pharma Ireland Limited Nanoparticulate meloxicam formulations
GB0418791D0 (en) * 2004-08-23 2004-09-22 Glaxo Group Ltd Novel process
US9149433B2 (en) * 2004-11-30 2015-10-06 Basf Corporation Method for formation of micro-prilled polymers
JP2008545808A (ja) * 2005-05-23 2008-12-18 エラン・ファルマ・インターナショナル・リミテッド 血小板凝集阻害薬を含むナノ粒子状および制御放出組成物
CL2007002689A1 (es) 2006-09-18 2008-04-18 Vitae Pharmaceuticals Inc Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
EP2172193A1 (de) 2008-10-02 2010-04-07 Capsulution Nanoscience AG Verbesserte Nanopartikel-Zusammensetzungen schlecht löslicher Verbindungen
US7828996B1 (en) 2009-03-27 2010-11-09 Abbott Cardiovascular Systems Inc. Method for the manufacture of stable, nano-sized particles
AR077692A1 (es) 2009-08-06 2011-09-14 Vitae Pharmaceuticals Inc Sales de 2-((r)-(3-clorofenil) ((r)-1-((s) -2-(metilamino)-3-((r)-tetrahidro-2h-piran-3-il) propilcarbamoil) piperidin -3-il) metoxi) etilcarbamato de metilo
JP5499703B2 (ja) * 2009-12-28 2014-05-21 ライオン株式会社 イブプロフェン含有製剤
JP6166721B2 (ja) 2011-07-22 2017-07-19 ケモセントリックス， インコーポレイテッド ４−ｔｅｒｔ−ブチル−Ｎ−［４−クロロ−２−（１−オキシ−ピリジン−４−カルボニル）−フェニル］−ベンゼンスルホンアミドのナトリウム塩の多形
WO2013016174A1 (en) 2011-07-22 2013-01-31 Chemocentryx, Inc. A crystalline form of the sodium salt of 4-tert-butyl-n-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzene sulfonamide
CN103906744A (zh) 2011-09-01 2014-07-02 葛兰素集团有限公司 新晶型
KR101794032B1 (ko) * 2011-09-21 2017-11-07 (주)바이오시네틱스 나노입자 제조방법
US9393202B2 (en) * 2013-04-26 2016-07-19 Chiesi Farmaceutici S.P.A Particle size reduction of an antimuscarinic compound
CR20160598A (es) 2014-06-25 2017-03-10 Glaxosmithkline Intelectual Property Dev Ltd Sales cristalinas de (s)-6-((1-acetilpiperidin-4-il) amino)-n-(3-(3,4-dihidroisoquinolin-2(1h)-il)-2-hidroxipropil) pirimidino-4-carboxamida
JP2017527574A (ja) 2014-09-08 2017-09-21 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ ２−（４−（４−エトキシ−６−オキソ−１，６−ジヒドロピリジン−３−イル）−２−フルオロフェニル）−ｎ−（５−（１，１，１−トリフルオロ−２−メチルプロパン−２−イル）イソオキサゾール−３−イル）アセトアミドの結晶形
WO2016086950A1 (en) 2014-12-03 2016-06-09 Rontis Hellas S.A. Pharmaceutical composition containing non-lipophilic hydrophobic drug and process for the preparation thereof
CN107001810A (zh) 2014-12-15 2017-08-01 M技术株式会社 有机物微粒的制造方法及有机物微粒的改性方法
EP3528792A1 (de) 2016-10-20 2019-08-28 Dukebox SP. Z O.O. Verfahren zur herstellung einer lösung aus nsaid-nanopartikeln
JPWO2020179701A1 (de) 2019-03-01 2020-09-10
US20220287985A1 (en) 2019-08-16 2022-09-15 Hiroshima Metal & Machinery Co., Ltd Organic nanoparticle production method and organic nanoparticles

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IT1227626B (it) * 1988-11-28 1991-04-23 Vectorpharma Int Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione
SE464743B (sv) * 1989-06-21 1991-06-10 Ytkemiska Inst Foerfarande foer framstaellning av laekemedelspartiklar
DK546289D0 (da) * 1989-11-02 1989-11-02 Danochemo As Carotenoidpulvere
IT1243342B (it) * 1990-07-13 1994-06-10 Farcon Ag Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles

Also Published As

Publication number Publication date
AU4396493A (en) 1994-01-04
WO1993025190A1 (en) 1993-12-23
DK0644755T3 (da) 1997-09-22
JP2009197003A (ja) 2009-09-03
MX9303452A (es) 1994-01-31
ES2101323T3 (es) 1997-07-01
DE69309056T2 (de) 1997-09-18
AU677783B2 (en) 1997-05-08
HUT70952A (en) 1995-11-28
CA2118517A1 (en) 1993-12-23
JP4439590B2 (ja) 2010-03-24
EP0644755A1 (de) 1995-03-29
EP0644755B1 (de) 1997-03-19
CA2118517C (en) 2003-10-14
JPH08501073A (ja) 1996-02-06
HU9403543D0 (en) 1995-02-28
GR3022880T3 (en) 1997-06-30
DE69309056D1 (de) 1997-04-24

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