ATE144530T1 - Glutathionderivat - Google Patents
GlutathionderivatInfo
- Publication number
- ATE144530T1 ATE144530T1 AT91904331T AT91904331T ATE144530T1 AT E144530 T1 ATE144530 T1 AT E144530T1 AT 91904331 T AT91904331 T AT 91904331T AT 91904331 T AT91904331 T AT 91904331T AT E144530 T1 ATE144530 T1 AT E144530T1
- Authority
- AT
- Austria
- Prior art keywords
- lower alkoxy
- different
- hydroxyl
- same
- alkyl
- Prior art date
Links
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical class OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 208000019423 liver disease Diseases 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3674590 | 1990-02-17 | ||
| JP13360090 | 1990-05-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE144530T1 true ATE144530T1 (de) | 1996-11-15 |
Family
ID=26375835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91904331T ATE144530T1 (de) | 1990-02-17 | 1991-02-15 | Glutathionderivat |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5541162A (de) |
| EP (1) | EP0469156B1 (de) |
| KR (1) | KR970001509B1 (de) |
| AT (1) | ATE144530T1 (de) |
| CA (1) | CA2050929A1 (de) |
| DE (1) | DE69122812T2 (de) |
| ES (1) | ES2093091T3 (de) |
| UA (1) | UA21900A (de) |
| WO (1) | WO1991012262A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991016065A1 (fr) * | 1990-04-26 | 1991-10-31 | Senju Pharmaceutical Co., Ltd. | Inhibiteur de troubles hepatiques |
| CA2099346A1 (en) * | 1992-07-17 | 1994-01-18 | Shinji Ohmori | Lipid metabolism improving composition |
| US5616563A (en) * | 1992-12-07 | 1997-04-01 | University Of Maryland Baltimore Campus | Glutathione N-hydroxycarbamoyl thioesters and method of inhibiting neoplastic growth |
| CA2213266A1 (en) * | 1996-09-04 | 1998-03-04 | Hideki Tsuruoka | Method for isolation and purification of s-(1,2-dicarboxyethyl) glutathione |
| US20030203006A1 (en) * | 1997-10-29 | 2003-10-30 | Ajinomoto Co. Inc. | Immunomodulator |
| US6197749B1 (en) * | 1997-10-29 | 2001-03-06 | Ajinomoto Co., Inc. | Method of suppressing immune responses by reducing intracellular content of glutathione in macrophages and monocytes |
| EP1004302A3 (de) * | 1998-10-29 | 2003-06-04 | Ajinomoto Co., Inc. | Immunomodulator |
| RU2178710C1 (ru) * | 2001-02-08 | 2002-01-27 | Кожемякин Леонид Андреевич | Индивидуальные вещества, полученные на основе химического взаимодействия дисульфидсодержащих пептидов с производными пуриновых или пиримидиновых оснований, фармацевтические композиции и препараты на их основе, способы их применения для лечения инфекционных заболеваний и профилактики осложнений |
| US6743433B2 (en) * | 2001-07-06 | 2004-06-01 | Nicholas V. Perricone | Treatment of acne using alkanolamine compositions |
| US7172905B2 (en) * | 2001-08-07 | 2007-02-06 | The University Of Chicago | Polypeptide immobilization |
| AU2003247907A1 (en) * | 2002-07-05 | 2004-01-23 | University Of Chicago | Characterization of biochips containing self-assembled monolayers with maldi-tof-ms |
| US20100112088A1 (en) * | 2003-08-29 | 2010-05-06 | Jay Pravda | Materials and methods for treatment of disorders associated with oxidative stress |
| GB0520845D0 (en) * | 2005-10-14 | 2005-11-23 | Hofmann Thomas F | Salt enhancing compounds and use |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4537718A (en) * | 1982-10-26 | 1985-08-27 | Columbia University In The City Of New York | Impermeant spectroscopic probes |
| US4710489A (en) * | 1985-04-22 | 1987-12-01 | Cornell Research Foundation, Inc. | Glutathione delivery system |
| JP2815179B2 (ja) * | 1989-07-14 | 1998-10-27 | 千寿製薬株式会社 | 抗炎症および/または抗アレルギー剤 |
| JP2919870B2 (ja) * | 1989-09-29 | 1999-07-19 | 千寿製薬株式会社 | 肝障害抑制剤 |
| WO1991016065A1 (fr) * | 1990-04-26 | 1991-10-31 | Senju Pharmaceutical Co., Ltd. | Inhibiteur de troubles hepatiques |
| CA2099346A1 (en) * | 1992-07-17 | 1994-01-18 | Shinji Ohmori | Lipid metabolism improving composition |
-
1991
- 1991-02-15 ES ES91904331T patent/ES2093091T3/es not_active Expired - Lifetime
- 1991-02-15 WO PCT/JP1991/000217 patent/WO1991012262A1/ja not_active Ceased
- 1991-02-15 UA UA5010147A patent/UA21900A/uk unknown
- 1991-02-15 CA CA002050929A patent/CA2050929A1/en not_active Abandoned
- 1991-02-15 EP EP91904331A patent/EP0469156B1/de not_active Expired - Lifetime
- 1991-02-15 KR KR1019910701303A patent/KR970001509B1/ko not_active Expired - Fee Related
- 1991-02-15 DE DE69122812T patent/DE69122812T2/de not_active Expired - Fee Related
- 1991-02-15 AT AT91904331T patent/ATE144530T1/de not_active IP Right Cessation
-
1994
- 1994-02-18 US US08/198,373 patent/US5541162A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2050929A1 (en) | 1991-08-18 |
| EP0469156A1 (de) | 1992-02-05 |
| EP0469156A4 (en) | 1993-08-04 |
| KR920701240A (ko) | 1992-08-11 |
| US5541162A (en) | 1996-07-30 |
| DE69122812T2 (de) | 1997-03-20 |
| KR970001509B1 (ko) | 1997-02-11 |
| ES2093091T3 (es) | 1996-12-16 |
| DE69122812D1 (de) | 1996-11-28 |
| UA21900A (uk) | 1998-04-30 |
| EP0469156B1 (de) | 1996-10-23 |
| WO1991012262A1 (fr) | 1991-08-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |