DE69122812D1 - Glutathionderivat - Google Patents

Glutathionderivat

Info

Publication number
DE69122812D1
DE69122812D1 DE69122812T DE69122812T DE69122812D1 DE 69122812 D1 DE69122812 D1 DE 69122812D1 DE 69122812 T DE69122812 T DE 69122812T DE 69122812 T DE69122812 T DE 69122812T DE 69122812 D1 DE69122812 D1 DE 69122812D1
Authority
DE
Germany
Prior art keywords
glutathion
derivative
lower alkoxy
different
hydroxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69122812T
Other languages
English (en)
Other versions
DE69122812T2 (de
Inventor
Shinji Ohmori
Kazumi Ogata
Takahiro Sakaue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69122812D1 publication Critical patent/DE69122812D1/de
Publication of DE69122812T2 publication Critical patent/DE69122812T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69122812T 1990-02-17 1991-02-15 Glutathionderivat Expired - Fee Related DE69122812T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3674590 1990-02-17
JP13360090 1990-05-23
PCT/JP1991/000217 WO1991012262A1 (en) 1990-02-17 1991-02-15 Glutathione derivative

Publications (2)

Publication Number Publication Date
DE69122812D1 true DE69122812D1 (de) 1996-11-28
DE69122812T2 DE69122812T2 (de) 1997-03-20

Family

ID=26375835

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69122812T Expired - Fee Related DE69122812T2 (de) 1990-02-17 1991-02-15 Glutathionderivat

Country Status (9)

Country Link
US (1) US5541162A (de)
EP (1) EP0469156B1 (de)
KR (1) KR970001509B1 (de)
AT (1) ATE144530T1 (de)
CA (1) CA2050929A1 (de)
DE (1) DE69122812T2 (de)
ES (1) ES2093091T3 (de)
UA (1) UA21900A (de)
WO (1) WO1991012262A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991016337A1 (en) * 1990-04-26 1991-10-31 Senju Pharmaceutical Co., Ltd. S-(lower fatty acid)-substituted glutathione derivative
TW225992B (de) * 1992-07-17 1994-07-01 Senju Pharma Co
US5616563A (en) * 1992-12-07 1997-04-01 University Of Maryland Baltimore Campus Glutathione N-hydroxycarbamoyl thioesters and method of inhibiting neoplastic growth
CA2213266A1 (en) * 1996-09-04 1998-03-04 Hideki Tsuruoka Method for isolation and purification of s-(1,2-dicarboxyethyl) glutathione
US6197749B1 (en) * 1997-10-29 2001-03-06 Ajinomoto Co., Inc. Method of suppressing immune responses by reducing intracellular content of glutathione in macrophages and monocytes
US20030203006A1 (en) * 1997-10-29 2003-10-30 Ajinomoto Co. Inc. Immunomodulator
EP1004302A3 (de) * 1998-10-29 2003-06-04 Ajinomoto Co., Inc. Immunomodulator
US6743433B2 (en) * 2001-07-06 2004-06-01 Nicholas V. Perricone Treatment of acne using alkanolamine compositions
US7172905B2 (en) * 2001-08-07 2007-02-06 The University Of Chicago Polypeptide immobilization
AU2003247907A1 (en) * 2002-07-05 2004-01-23 University Of Chicago Characterization of biochips containing self-assembled monolayers with maldi-tof-ms
US20100112088A1 (en) * 2003-08-29 2010-05-06 Jay Pravda Materials and methods for treatment of disorders associated with oxidative stress
GB0520845D0 (en) * 2005-10-14 2005-11-23 Hofmann Thomas F Salt enhancing compounds and use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537718A (en) * 1982-10-26 1985-08-27 Columbia University In The City Of New York Impermeant spectroscopic probes
US4710489A (en) * 1985-04-22 1987-12-01 Cornell Research Foundation, Inc. Glutathione delivery system
JP2815179B2 (ja) * 1989-07-14 1998-10-27 千寿製薬株式会社 抗炎症および／または抗アレルギー剤
JP2919870B2 (ja) * 1989-09-29 1999-07-19 千寿製薬株式会社 肝障害抑制剤
WO1991016337A1 (en) * 1990-04-26 1991-10-31 Senju Pharmaceutical Co., Ltd. S-(lower fatty acid)-substituted glutathione derivative
TW225992B (de) * 1992-07-17 1994-07-01 Senju Pharma Co

Also Published As

Publication number Publication date
CA2050929A1 (en) 1991-08-18
KR920701240A (ko) 1992-08-11
DE69122812T2 (de) 1997-03-20
KR970001509B1 (ko) 1997-02-11
EP0469156A1 (de) 1992-02-05
EP0469156A4 (en) 1993-08-04
US5541162A (en) 1996-07-30
ATE144530T1 (de) 1996-11-15
UA21900A (uk) 1998-04-30
EP0469156B1 (de) 1996-10-23
ES2093091T3 (es) 1996-12-16
WO1991012262A1 (en) 1991-08-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee