ATE138263T1 - Herstellungsverfahren für biologisch aktives material enthaltende polymere mikrokapseln - Google Patents

Herstellungsverfahren für biologisch aktives material enthaltende polymere mikrokapseln

Info

Publication number
ATE138263T1
ATE138263T1 AT93200438T AT93200438T ATE138263T1 AT E138263 T1 ATE138263 T1 AT E138263T1 AT 93200438 T AT93200438 T AT 93200438T AT 93200438 T AT93200438 T AT 93200438T AT E138263 T1 ATE138263 T1 AT E138263T1
Authority
AT
Austria
Prior art keywords
active material
biologically active
production process
capsules containing
containing biologically
Prior art date
Application number
AT93200438T
Other languages
English (en)
Inventor
Cardina Anna Maria Chris Dirix
Hendrikus Johannes Maria Kamp
Anthonius Paulus Sam
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE138263T1 publication Critical patent/ATE138263T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT93200438T 1992-02-18 1993-02-16 Herstellungsverfahren für biologisch aktives material enthaltende polymere mikrokapseln ATE138263T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92200466 1992-02-18

Publications (1)

Publication Number Publication Date
ATE138263T1 true ATE138263T1 (de) 1996-06-15

Family

ID=8210436

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93200438T ATE138263T1 (de) 1992-02-18 1993-02-16 Herstellungsverfahren für biologisch aktives material enthaltende polymere mikrokapseln

Country Status (16)

Country Link
US (1) US5389379A (de)
EP (1) EP0556917B1 (de)
JP (1) JPH05337360A (de)
KR (1) KR930017574A (de)
AT (1) ATE138263T1 (de)
AU (1) AU658715B2 (de)
CA (1) CA2089354A1 (de)
DE (1) DE69302721T2 (de)
DK (1) DK0556917T3 (de)
ES (1) ES2090836T3 (de)
FI (1) FI930672L (de)
GR (1) GR3020417T3 (de)
MX (1) MX9300851A (de)
NO (1) NO930557L (de)
NZ (1) NZ245914A (de)
ZA (1) ZA93929B (de)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693338A (en) 1994-09-29 1997-12-02 Emisphere Technologies, Inc. Diketopiperazine-based delivery systems
US6344213B1 (en) * 1996-03-29 2002-02-05 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US5714167A (en) 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5578323A (en) 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US5541155A (en) 1994-04-22 1996-07-30 Emisphere Technologies, Inc. Acids and acid salts and their use in delivery systems
US5443841A (en) 1992-06-15 1995-08-22 Emisphere Technologies, Inc. Proteinoid microspheres and methods for preparation and use thereof
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US6099856A (en) 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US5811127A (en) 1992-06-15 1998-09-22 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5792451A (en) 1994-03-02 1998-08-11 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US6383470B1 (en) 1992-09-26 2002-05-07 Thomas Fritzsch Microparticle preparations made of biodegradable copolymers
US5401516A (en) 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5958457A (en) 1993-04-22 1999-09-28 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US5709861A (en) 1993-04-22 1998-01-20 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US20010003001A1 (en) 1993-04-22 2001-06-07 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6461643B2 (en) * 1993-04-22 2002-10-08 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5643957A (en) 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
DE69428040T2 (de) 1993-04-22 2002-05-29 Emisphere Technologies, Inc. Orale darreichungsform
US5650173A (en) * 1993-11-19 1997-07-22 Alkermes Controlled Therapeutics Inc. Ii Preparation of biodegradable microparticles containing a biologically active agent
US6090958A (en) 1995-03-31 2000-07-18 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5650386A (en) 1995-03-31 1997-07-22 Emisphere Technologies, Inc. Compositions for oral delivery of active agents
US5989539A (en) 1995-03-31 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5866536A (en) 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5965121A (en) 1995-03-31 1999-10-12 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
BR9604880A (pt) 1995-03-31 1998-05-19 Emisphere Tech Inc Composto composição forma de unidade de dosagem métodos para administração de um agente biologicamente ativo para preparar uma composição para administração de um agente ativo e para preparar um composto e composição farmacológica
US5820881A (en) 1995-04-28 1998-10-13 Emisphere Technologies, Inc. Microspheres of diamide-dicarboxylic acids
US5667806A (en) 1995-06-07 1997-09-16 Emisphere Technologies, Inc. Spray drying method and apparatus
US6051258A (en) 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US5824345A (en) 1995-06-07 1998-10-20 Emisphere Technologies, Inc. Fragrances and flavorants
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
CN1055417C (zh) * 1995-09-05 2000-08-16 中国科学院成都有机化学研究所 一种核-壳结构的蛋白高分子微球及其制法
WO1997010197A1 (en) 1995-09-11 1997-03-20 Emisphere Technologies, Inc. METHOD FOR PREPARING φ-AMINOALKANOIC ACID DERIVATIVES FROM CYCLOALKANONES
IE960308A1 (en) 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
WO1997047288A1 (en) 1996-06-14 1997-12-18 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
US6391303B1 (en) 1996-11-18 2002-05-21 Emisphere Technologies, Inc. Methods and compositions for inducing oral tolerance in mammals
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US5876710A (en) 1997-02-07 1999-03-02 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US5939381A (en) 1997-02-07 1999-08-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5804688A (en) 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5879681A (en) 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) * 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6060513A (en) 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5990166A (en) 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5945126A (en) * 1997-02-13 1999-08-31 Oakwood Laboratories L.L.C. Continuous microsphere process
US5863944A (en) 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
US5989463A (en) * 1997-09-24 1999-11-23 Alkermes Controlled Therapeutics, Inc. Methods for fabricating polymer-based controlled release devices
US6270802B1 (en) 1998-10-28 2001-08-07 Oakwood Laboratories L.L.C. Method and apparatus for formulating microspheres and microcapsules
US6498153B1 (en) 1998-12-31 2002-12-24 Akzo Nobel N.V. Extended release growth promoting two component composition
EP1223915B1 (de) * 1999-10-29 2005-12-21 Nektar Therapeutics Trockenpulverzusammensetzungen mit verbesserter dispersität
US6767637B2 (en) * 2000-12-13 2004-07-27 Purdue Research Foundation Microencapsulation using ultrasonic atomizers
US9101949B2 (en) * 2005-08-04 2015-08-11 Eilaz Babaev Ultrasonic atomization and/or seperation system
US20070031611A1 (en) * 2005-08-04 2007-02-08 Babaev Eilaz P Ultrasound medical stent coating method and device
US7896539B2 (en) * 2005-08-16 2011-03-01 Bacoustics, Llc Ultrasound apparatus and methods for mixing liquids and coating stents
WO2007070957A1 (en) * 2005-12-21 2007-06-28 Monash University Process and apparatus for generating particles
TWI318894B (en) * 2006-08-07 2010-01-01 Ind Tech Res Inst System for fabricating nano particles
US20080142616A1 (en) * 2006-12-15 2008-06-19 Bacoustics Llc Method of Producing a Directed Spray
US7753285B2 (en) 2007-07-13 2010-07-13 Bacoustics, Llc Echoing ultrasound atomization and/or mixing system
US7780095B2 (en) 2007-07-13 2010-08-24 Bacoustics, Llc Ultrasound pumping apparatus
US10149826B2 (en) * 2015-01-20 2018-12-11 Hyalo Technologies, LLC Method of preparing microspheres

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
US4530840A (en) * 1982-07-29 1985-07-23 The Stolle Research And Development Corporation Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents
FR2618674B1 (fr) * 1987-07-30 1990-06-15 Ire Celltarg Sa Microparticules comportant un polymere biodegradable controlant la liberation d'un principe actif antimalarique, compositions pharmaceutiques en comprenant et procede de preparation
US5019400A (en) * 1989-05-01 1991-05-28 Enzytech, Inc. Very low temperature casting of controlled release microspheres
ES2084698T5 (es) * 1989-05-04 2005-03-01 Southern Research Institute Procedimiento de encapsulacion.
US5091187A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs

Also Published As

Publication number Publication date
NO930557D0 (no) 1993-02-17
EP0556917B1 (de) 1996-05-22
FI930672A7 (fi) 1993-08-19
FI930672L (fi) 1993-08-19
AU658715B2 (en) 1995-04-27
JPH05337360A (ja) 1993-12-21
NO930557L (no) 1993-08-19
ZA93929B (en) 1993-09-10
AU3313493A (en) 1993-08-19
CA2089354A1 (en) 1993-08-19
US5389379A (en) 1995-02-14
DK0556917T3 (da) 1996-09-16
NZ245914A (en) 1995-02-24
FI930672A0 (fi) 1993-02-16
EP0556917A1 (de) 1993-08-25
ES2090836T3 (es) 1996-10-16
GR3020417T3 (en) 1996-10-31
DE69302721D1 (de) 1996-06-27
DE69302721T2 (de) 1996-09-19
KR930017574A (ko) 1993-09-20
MX9300851A (es) 1994-08-31

Similar Documents

Publication Publication Date Title
ATE138263T1 (de) Herstellungsverfahren für biologisch aktives material enthaltende polymere mikrokapseln
EP0193725A3 (en) Process for spinning hollow fiber membranes
FR2435341A1 (fr) Procede de production d'une matiere composite en feuille
HU9401329D0 (en) Process for producing microcapsules
Andrianov et al. Controlled release using ionotropic polyphosphazene hydrogels
GR3015885T3 (en) A process for preparing a microporous membrane and such a membrane.
ATE87540T1 (de) Verfahren und vorrichtung zur herstellung von polymermaterial.
FR2576602B1 (fr) Procede de fabrication de poudre de polyamide et poudre ainsi obtenue
AU585377B2 (en) Controlled release pharmaceutical composition
BR9105782A (pt) Processo de tratamento farmacotecnico de uma substancia ativa,injetavel e,de formulacoes parentericas
BE901704A (fr) Procede d'encapsulation, notamment de cellules, dans des membranes semi-permeables.
EP0248531A3 (de) Verkapselte Nukleinsäuren
BR9406541A (pt) Processo para a produção de filamentos de celulose a partir de uma solução de celulose em um solvente orgânico célula de fiação para a coagulação de filamentos e de celulose formados a partir de uma solução de celulose em um solvente orgânico e filamentos de celulose
EP0235603A3 (de) Verfahren zum Herstellen gleichförmiger Tröpfchen
DE69106827D1 (de) Verfahren zur Herstellung von Mikrokapseln und Gegenstände, welche eingekapseltes Material enthalten.
ATE147622T1 (de) Verfahren zur herstellung von in lösungsmitteln verdünnbaren mikroträgern
DE59606245D1 (de) Verfahren zur Herstellung von sphärischen Mikropartikeln auf Celluloseacetat-Basis
ATE75634T1 (de) Verfahren zum mikroeinkapseln, anwendung von polymeren, die dabei hergestellt werden und zusammensetzungen, welche die polymere enthalten.
EP0411461A3 (en) Hydrophilic polycarbodiimide polymer,pulp-like material consisting of said hydrophilic polycarbodiimide polymer, and process for producing said polymer or said material
ATE277684T1 (de) Mikrokapseln
Buck et al. Process for Spinning Hollow Fiber Membranes
ATE71161T1 (de) Naehgarn sowie verfahren zur herstellung desselben.
DE69027787D1 (de) Verfahren zur Herstellung von gefärbten und genau sphärischen, feinkörnigen Polymeren
FR2600080B1 (fr) Polymere naturel comprenant de la polygalactosamine, et ses sels, leur obtention et applications
DE69003448D1 (de) Verfahren zur Herstellung von "Oxoprodukten" über ein Plasma und Plasmareaktor einschliessende Anlage, verwendbar beim Verfahren.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee