ATE137963T1 - Lh-rh-analoga enthaltende formulierungen - Google Patents

Lh-rh-analoga enthaltende formulierungen

Info

Publication number
ATE137963T1
ATE137963T1 AT92111535T AT92111535T ATE137963T1 AT E137963 T1 ATE137963 T1 AT E137963T1 AT 92111535 T AT92111535 T AT 92111535T AT 92111535 T AT92111535 T AT 92111535T AT E137963 T1 ATE137963 T1 AT E137963T1
Authority
AT
Austria
Prior art keywords
analogs
formulations containing
relates
aerosol formulations
suspension aerosol
Prior art date
Application number
AT92111535T
Other languages
English (en)
Inventor
Akwete L Adjei
James W Kesterson
Edwin S Johnson
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/934,874 external-priority patent/US4851211A/en
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE137963T1 publication Critical patent/ATE137963T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Saccharide Compounds (AREA)
  • Seasonings (AREA)
  • Cosmetics (AREA)
AT92111535T 1986-11-25 1987-11-23 Lh-rh-analoga enthaltende formulierungen ATE137963T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/934,874 US4851211A (en) 1986-11-25 1986-11-25 LHRH analog formulations
US07/114,359 US4897256A (en) 1986-11-25 1987-11-04 LHRH analog formulations

Publications (1)

Publication Number Publication Date
ATE137963T1 true ATE137963T1 (de) 1996-06-15

Family

ID=26812097

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92111535T ATE137963T1 (de) 1986-11-25 1987-11-23 Lh-rh-analoga enthaltende formulierungen

Country Status (7)

Country Link
US (1) US4897256A (de)
EP (2) EP0275404B1 (de)
JP (1) JP2533586B2 (de)
AT (1) ATE137963T1 (de)
CA (1) CA1300009C (de)
DE (2) DE3751811T2 (de)
ES (2) ES2040727T3 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5776434A (en) 1988-12-06 1998-07-07 Riker Laboratories, Inc. Medicinal aerosol formulations
US4994439A (en) * 1989-01-19 1991-02-19 California Biotechnology Inc. Transmembrane formulations for drug administration
US5011678A (en) * 1989-02-01 1991-04-30 California Biotechnology Inc. Composition and method for administration of pharmaceutically active substances
WO1994008599A1 (en) * 1992-10-14 1994-04-28 The Regents Of The University Of Colorado Ion-pairing of drugs for improved efficacy and delivery
CA2167538A1 (en) * 1993-07-19 1995-02-02 Tsutomu Arakawa Stabilization of aerosolized proteins
US5711934A (en) * 1994-04-11 1998-01-27 Abbott Laboratories Process for the continuous milling of aerosol pharmaceutical formulations in aerosol propellants
US5677184A (en) * 1994-04-19 1997-10-14 Takeda Chemical Industries, Ltd. CHO cells that express human LH-RH receptor
US5635159A (en) * 1994-08-26 1997-06-03 Abbott Laboratories Aerosol drug formulations containing polyglycolyzed glycerides
CN1088580C (zh) 1994-12-22 2002-08-07 阿斯特拉公司 气溶胶药物制剂
US7572252B1 (en) * 1995-06-07 2009-08-11 Alza Corporation Electrotransport agent delivery method and apparatus
US5635161A (en) * 1995-06-07 1997-06-03 Abbott Laboratories Aerosol drug formulations containing vegetable oils
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US20020052310A1 (en) 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
US5932547A (en) * 1996-07-03 1999-08-03 Alza Corporation Non-aqueous polar aprotic peptide formulations
RO119862B1 (ro) * 1996-07-03 2005-05-30 Alza Corporation Formulare stabilă neapoasă şi procedeu pentru prepararea acesteia
US5981489A (en) * 1996-07-18 1999-11-09 Alza Corporation Non-aqueous protic peptide formulations
CA2277801C (en) * 1997-01-16 2002-10-15 Massachusetts Institute Of Technology Preparation of particles for inhalation
EP1498115A1 (de) * 1997-01-16 2005-01-19 Massachusetts Institute Of Technology Zubereitung von partikelhaltigen Arzneimitteln zur Inhalation
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US6099851A (en) * 1998-06-02 2000-08-08 Weisman; Kenneth M. Therapeutic uses of leuprolide acetate
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
DE10043509A1 (de) * 2000-09-01 2002-03-14 Asta Medica Ag Feste Peptidzubereitungen für die Inhalation und deren Herstellung
AU2002230993B2 (en) 2000-12-29 2006-02-02 Alkermes, Inc. Particles for inhalation having sustained release properties
US20030035774A1 (en) * 2001-07-18 2003-02-20 Adjei Akwete L. Salt/ion pair medicinal aerosol formulation
WO2003043585A2 (en) 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Improved particulate compositions for pulmonary delivery
DE10214031A1 (de) * 2002-03-27 2004-02-19 Pharmatech Gmbh Verfahren zur Herstellung und Anwendung von Mikro- und Nanoteilchen durch aufbauende Mikronisation
ATE412411T1 (de) 2003-02-27 2008-11-15 Wisconsin Alumni Res Found Pmcol zur behandlung von prostatakrebs
US7279181B2 (en) * 2003-06-03 2007-10-09 Ferro Corporation Method for preparation of particles from solution-in-supercritical fluid or compressed gas emulsions
WO2005077339A1 (en) * 2004-02-10 2005-08-25 E.I. Dupont De Nemours And Company Process for preparing stable sol of pharmaceutical ingredients and hydrofluorocarbon comprising milling the said sol, then transfert it into a canister
US7500479B2 (en) * 2004-04-23 2009-03-10 Philip Morris Usa Inc. Aerosol generators and methods for producing aerosols

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1063512A (en) * 1962-11-30 1967-03-30 Benger Lab Ltd Aerosols
US3898329A (en) * 1971-09-17 1975-08-05 Sami I Said Vasoactive intestinal peptide, composition and method
GB1454105A (en) * 1972-11-04 1976-10-27 Hoechst Ag Preparation containing luteinizing hormone-releasing factor
DE2254061A1 (de) * 1972-11-04 1974-05-16 Hoechst Ag Lh-releasing hormon zur nasalen applikation
FR2320107A1 (fr) * 1975-08-05 1977-03-04 Anvar Nouveaux adjuvants immunologiques, procede pour leur obtention et compositions les contenant
US4405598A (en) * 1976-01-30 1983-09-20 Fisons, Limited Composition for treating asthma
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
US4438029A (en) * 1978-01-19 1984-03-20 Research Corporation Synthetic peptides
JPS5819669B2 (ja) * 1978-10-28 1983-04-19 白井松新薬株式会社 新規生理活性ペプチド化合物及びその製造法
JPS57188526A (en) * 1981-05-14 1982-11-19 Takeda Chem Ind Ltd Peptide-containing pharmaceutical preparation
DE3371281D1 (en) * 1982-12-10 1987-06-11 Syntex Inc Lhrh preparations for intranasal administration
US4476116A (en) * 1982-12-10 1984-10-09 Syntex (U.S.A.) Inc. Polypeptides/chelating agent nasal compositions having enhanced peptide absorption
US4481191A (en) * 1983-03-30 1984-11-06 The Regents Of The University Of California Method for controlling blood pressure
GB8322178D0 (en) * 1983-08-17 1983-09-21 Sterwin Ag Preparing aerosol compositions

Also Published As

Publication number Publication date
DE3785570D1 (de) 1993-05-27
ES2040727T3 (es) 1993-11-01
DE3751811T2 (de) 1996-11-28
EP0275404A1 (de) 1988-07-27
CA1300009C (en) 1992-05-05
ES2089301T3 (es) 1996-10-01
JP2533586B2 (ja) 1996-09-11
DE3751811D1 (de) 1996-06-20
EP0510731A1 (de) 1992-10-28
US4897256A (en) 1990-01-30
JPS63211237A (ja) 1988-09-02
EP0510731B1 (de) 1996-05-15
EP0275404B1 (de) 1993-04-21
DE3785570T2 (de) 1993-11-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee