ATE129013T1 - Steroid 5-alpha-reduktase. - Google Patents

Steroid 5-alpha-reduktase.

Info

Publication number
ATE129013T1
ATE129013T1 AT91909339T AT91909339T ATE129013T1 AT E129013 T1 ATE129013 T1 AT E129013T1 AT 91909339 T AT91909339 T AT 91909339T AT 91909339 T AT91909339 T AT 91909339T AT E129013 T1 ATE129013 T1 AT E129013T1
Authority
AT
Austria
Prior art keywords
preparation
steroid
alpha
disclosed
sequences
Prior art date
Application number
AT91909339T
Other languages
English (en)
Inventor
Stefan Andersson
David W Russell
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Application granted granted Critical
Publication of ATE129013T1 publication Critical patent/ATE129013T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
    • C12Y103/01022—3-Oxo-5alpha-steroid 4-dehydrogenase (NADP+) (1.3.1.22), i.e. cortisone alpha-reductase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT91909339T 1990-04-30 1991-04-25 Steroid 5-alpha-reduktase. ATE129013T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51766190A 1990-04-30 1990-04-30

Publications (1)

Publication Number Publication Date
ATE129013T1 true ATE129013T1 (de) 1995-10-15

Family

ID=24060703

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91909339T ATE129013T1 (de) 1990-04-30 1991-04-25 Steroid 5-alpha-reduktase.

Country Status (8)

Country Link
US (2) US5422262A (de)
EP (1) EP0528906B1 (de)
JP (1) JP3294844B2 (de)
AT (1) ATE129013T1 (de)
AU (1) AU642501B2 (de)
CA (1) CA2079454C (de)
DE (1) DE69113795T2 (de)
WO (1) WO1991017251A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69113795T2 (de) * 1990-04-30 1996-03-28 Board of Regents, the University of Texas System, Austin, Tex. Steroid 5-alpha-reduktase.
US5576191A (en) * 1994-06-17 1996-11-19 Immunex Corporation Cytokine that binds ST2
US5656613A (en) * 1995-01-04 1997-08-12 Merck & Co., Inc. Treatment of hyperandrogenic conditions
US20020170077A1 (en) * 1995-02-10 2002-11-14 Millennium Pharmaceuticals, Inc. Compositions and methods for the treatment and diagnosis of cardiovascular disease
US5968770A (en) * 1995-02-10 1999-10-19 Millennium Pharmaceuticals, Inc. Compositions and methods for the treatment and diagnosis of cardiovascular disease using rchd523 as a target
US6359194B1 (en) 1995-02-10 2002-03-19 Millennium Pharmaceuticals, Inc. Compositions and methods for the treatment and diagnosis of cardiovascular disease
IT1276662B1 (it) * 1995-04-04 1997-11-03 Uni Degli Studi Camerino Vaccini polinucleotidici
JP2000501603A (ja) * 1995-12-07 2000-02-15 ベイラー・カレッジ・オブ・メディスン 尿生殖洞由来増殖因子のヌクレオチドおよびアミノ酸配列
CA2247246A1 (en) 1996-02-16 1997-08-21 Millennium Pharmaceuticals, Inc. Compositions and methods for the treatment and diagnosis of cardiovascular disease
AU2666797A (en) * 1996-04-15 1997-11-07 Dyad Pharmaceutical Corporation Combination therapy for androgenic alopecia with antisense oligonucleotides and minoxidil
US6143950A (en) * 1996-04-18 2000-11-07 The Salk Institute For Biological Studies Plant steroid 5α reductase, DET2
EP0904295B1 (de) * 1996-05-15 2005-08-10 ALTANA Pharma AG Verfahren zur trennung und bestimmung von hydrophoben proteinen durch dünnschichtchromatographie
WO1999037986A2 (en) 1998-01-23 1999-07-29 University Of Southern California Androgen-metabolic gene mutations and prostate cancer risk
ES2347027T3 (es) 1998-05-22 2010-10-22 The Board Of Trustees Of The Leland Stanford Junior University Moleculas bifuncionales y terapias basadas en las mismas.
WO2001079504A1 (en) * 2000-04-13 2001-10-25 Millennium Pharmaceuticals, Inc. 23155 NOVEL PROTEIN HUMAN 5-α REDUCTASES AND USES THEREFOR
US6469150B1 (en) * 2000-05-22 2002-10-22 Pharmacopeia, Inc. Cloning and characterization of genes encoding bradykinin B1 receptor homologues from five mammalian species
JP2005512502A (ja) 2000-10-30 2005-05-12 ファルマシア・コーポレーション アスペルギルス・オクラセウス（Ａｓｐｅｒｇｉｌｌｕｓｏｃｈｒａｃｅｕｓ）１１アルファ水酸化酵素および酸化還元酵素
PT1343530E (pt) * 2000-11-09 2007-09-25 Astrazeneca Ab Composição farmacêutica oral contendo um copolímero de blocos
JP2002236307A (ja) * 2001-02-09 2002-08-23 Asahi Optical Co Ltd ズームストロボ装置
WO2006010038A2 (en) * 2004-07-08 2006-01-26 Biosearch Technologies, Inc. Inducible fluorescence assay
US20070036740A1 (en) * 2004-10-06 2007-02-15 Reed Kenneth C Modulation of hair growth
EP2671507A3 (de) 2005-04-28 2014-02-19 Proteus Digital Health, Inc. Pharma-Informatiksystem
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
FR2903999B1 (fr) * 2006-07-19 2008-09-05 Galderma Res & Dev S N C Snc Modulateurs de sc4mol dans le traitement de l'acne ou de l'hyperseborrhee
CA2752373C (en) 2009-02-20 2017-10-10 To-Bbb Holding B.V. Glutathione-based drug delivery system
US20120156138A1 (en) * 2009-04-14 2012-06-21 Smith Larry J Methods and Compositions for the Treatment of Medical Conditions Involving Cellular Reprogramming
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
WO2021145458A1 (ja) * 2020-01-16 2021-07-22 学校法人慶應義塾 胆汁酸を生成するための組成物
CN117630382A (zh) * 2023-11-25 2024-03-01 温州医科大学附属第二医院（温州医科大学附属育英儿童医院） 大鼠睾丸Leydig祖细胞标志蛋白及其筛选方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69113795T2 (de) * 1990-04-30 1996-03-28 Board of Regents, the University of Texas System, Austin, Tex. Steroid 5-alpha-reduktase.

Also Published As

Publication number Publication date
EP0528906A1 (de) 1993-03-03
US5679521A (en) 1997-10-21
JPH05507405A (ja) 1993-10-28
CA2079454A1 (en) 1991-10-31
CA2079454C (en) 2002-02-26
JP3294844B2 (ja) 2002-06-24
DE69113795D1 (de) 1995-11-16
US5422262A (en) 1995-06-06
DE69113795T2 (de) 1996-03-28
WO1991017251A1 (en) 1991-11-14
AU7857991A (en) 1991-11-27
AU642501B2 (en) 1993-10-21
EP0528906B1 (de) 1995-10-11

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