ATE128705T1 - Spiro-derivate von dibenzosuberan. - Google Patents
Spiro-derivate von dibenzosuberan.Info
- Publication number
- ATE128705T1 ATE128705T1 AT91107396T AT91107396T ATE128705T1 AT E128705 T1 ATE128705 T1 AT E128705T1 AT 91107396 T AT91107396 T AT 91107396T AT 91107396 T AT91107396 T AT 91107396T AT E128705 T1 ATE128705 T1 AT E128705T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- hydrogen
- dibenzosuberan
- spiro derivatives
- spiro
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 201000006474 Brain Ischemia Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010070511 Hypoxic-ischaemic encephalopathy Diseases 0.000 abstract 1
- 102000004868 N-Methyl-D-Aspartate Receptors Human genes 0.000 abstract 1
- 108090001041 N-Methyl-D-Aspartate Receptors Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000002555 anti-neurodegenerative effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- -1 spiro dibenzosuberane derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/96—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/12—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heat Sensitive Colour Forming Recording (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11812690 | 1990-05-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE128705T1 true ATE128705T1 (de) | 1995-10-15 |
Family
ID=14728685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91107396T ATE128705T1 (de) | 1990-05-07 | 1991-05-07 | Spiro-derivate von dibenzosuberan. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0456183B1 (de) |
| JP (1) | JPH04225953A (de) |
| KR (1) | KR910019978A (de) |
| AT (1) | ATE128705T1 (de) |
| CA (1) | CA2040750A1 (de) |
| DE (1) | DE69113505T2 (de) |
| DK (1) | DK0456183T3 (de) |
| ES (1) | ES2080182T3 (de) |
| GR (1) | GR3017868T3 (de) |
| HU (1) | HUT58057A (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5538986A (en) * | 1993-12-06 | 1996-07-23 | Schering Corporation | Tricyclic derivatives, compositions and methods of use |
| US5760246A (en) | 1996-12-17 | 1998-06-02 | Biller; Scott A. | Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method |
| UA73749C2 (en) * | 1999-11-01 | 2005-09-15 | Diarylenines | |
| ATE413388T1 (de) * | 2002-04-26 | 2008-11-15 | Schering Corp | Muskarin antagonisten |
| US7101917B2 (en) | 2003-04-14 | 2006-09-05 | Hoffmann-La Roche Inc. | Mitochrondrial permeability transition pore affinity labels and modulators |
| HRP20160180T1 (hr) | 2003-04-24 | 2016-03-25 | Incyte Holdings Corp | Derivati aza spiro alkana kao inhibitori metaloproteaza |
| BRPI0607768A2 (pt) | 2005-02-25 | 2009-10-06 | Irm Llc | compostos e composições contendo espiro como moduladores de receptores nucleares de hormÈnios esteróides, método para a preparação dos referidos compostos, usos relacionados, bem como métodos para modular a atividade de no mìnimo um receptor nuclear de hormÈnios esteróides |
| US9331663B2 (en) | 2011-06-07 | 2016-05-03 | Pioneer Corporation | Impedance matching device and control method |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8719199D0 (en) * | 1987-08-13 | 1987-09-23 | Merck Sharp & Dohme | Chemical compounds |
-
1991
- 1991-04-09 JP JP3104807A patent/JPH04225953A/ja active Pending
- 1991-04-18 CA CA002040750A patent/CA2040750A1/en not_active Abandoned
- 1991-05-04 KR KR1019910007257A patent/KR910019978A/ko not_active Ceased
- 1991-05-06 HU HU911520A patent/HUT58057A/hu unknown
- 1991-05-07 AT AT91107396T patent/ATE128705T1/de not_active IP Right Cessation
- 1991-05-07 ES ES91107396T patent/ES2080182T3/es not_active Expired - Lifetime
- 1991-05-07 DE DE69113505T patent/DE69113505T2/de not_active Expired - Fee Related
- 1991-05-07 EP EP91107396A patent/EP0456183B1/de not_active Expired - Lifetime
- 1991-05-07 DK DK91107396.3T patent/DK0456183T3/da active
-
1995
- 1995-10-25 GR GR950402972T patent/GR3017868T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2080182T3 (es) | 1996-02-01 |
| DE69113505T2 (de) | 1996-04-04 |
| HUT58057A (en) | 1992-01-28 |
| DE69113505D1 (de) | 1995-11-09 |
| KR910019978A (ko) | 1991-12-19 |
| JPH04225953A (ja) | 1992-08-14 |
| CA2040750A1 (en) | 1991-11-08 |
| EP0456183A3 (en) | 1992-04-22 |
| HU911520D0 (en) | 1991-11-28 |
| GR3017868T3 (en) | 1996-01-31 |
| EP0456183A2 (de) | 1991-11-13 |
| DK0456183T3 (da) | 1995-11-20 |
| EP0456183B1 (de) | 1995-10-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |