ATE124705T1 - Peptide und verfahren zur herstellung von zyklischen peptiden. - Google Patents

Peptide und verfahren zur herstellung von zyklischen peptiden.

Info

Publication number
ATE124705T1
ATE124705T1 AT91909390T AT91909390T ATE124705T1 AT E124705 T1 ATE124705 T1 AT E124705T1 AT 91909390 T AT91909390 T AT 91909390T AT 91909390 T AT91909390 T AT 91909390T AT E124705 T1 ATE124705 T1 AT E124705T1
Authority
AT
Austria
Prior art keywords
ser
substd
leu
protecting
asn
Prior art date
Application number
AT91909390T
Other languages
German (de)
English (en)
Inventor
Masutaka Ohsaki
Satoshi Kishida
Takashi Inoue
Original Assignee
Daicel Chem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daicel Chem filed Critical Daicel Chem
Application granted granted Critical
Publication of ATE124705T1 publication Critical patent/ATE124705T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT91909390T 1989-11-08 1990-11-07 Peptide und verfahren zur herstellung von zyklischen peptiden. ATE124705T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP29066089 1989-11-08

Publications (1)

Publication Number Publication Date
ATE124705T1 true ATE124705T1 (de) 1995-07-15

Family

ID=17758846

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91909390T ATE124705T1 (de) 1989-11-08 1990-11-07 Peptide und verfahren zur herstellung von zyklischen peptiden.

Country Status (9)

Country Link
US (2) US5428129A (enExample)
EP (1) EP0452514B1 (enExample)
JP (1) JPH0745517B2 (enExample)
KR (1) KR920701248A (enExample)
AT (1) ATE124705T1 (enExample)
CA (1) CA2045495A1 (enExample)
DE (1) DE69020722T2 (enExample)
DK (1) DK0452514T3 (enExample)
WO (1) WO1991007433A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2045495A1 (en) * 1989-11-08 1991-05-09 Masutaka Ohsaki Peptides and processes for producing cyclic peptides
WO1995034577A1 (en) * 1994-06-16 1995-12-21 Smithkline Beecham Corporation Template directed cyclization
US5661097A (en) † 1994-08-12 1997-08-26 The Dow Chemical Company Supported olefin polymerization catalyst
WO1996029343A1 (en) * 1995-03-20 1996-09-26 Kyowa Hakko Kogyo Co., Ltd. Novel calcitonin derivatives
US5962270A (en) * 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs
US6271198B1 (en) 1996-11-06 2001-08-07 Genentech, Inc. Constrained helical peptides and methods of making same
AU744812B2 (en) * 1998-04-15 2002-03-07 Aventis Pharmaceuticals Inc. Process for the preparation of resin-bound cyclic peptides
AU2003219787A1 (en) * 2002-02-14 2003-09-04 Bayer Pharmaceuticals Corporation Formulation strategies in stabilizing peptides in organic solvents and in dried states
DE10325049A1 (de) * 2003-06-02 2004-12-23 Merck Patent Gmbh Peptid- und Peptidmimetika-Derivate mit Integrin-Inhibitor-Eigenschaften III
WO2008109079A2 (en) * 2007-03-01 2008-09-12 Novetide, Ltd. High purity peptides

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4043992A (en) * 1969-06-30 1977-08-23 Kyowa Hakko Kogyo Co., Ltd. Method for preparing acylated products
JPS51128993A (en) * 1975-05-01 1976-11-10 Tanpakushitsu Kenkyu Shiyoureikai Process for preparing new polypeptides
US4161521A (en) * 1975-08-08 1979-07-17 Merck & Co., Inc. Somatostatin analogs
JPS5359688A (en) * 1976-11-11 1978-05-29 Tanpakushitsu Kenkiyuu Shiyour Production of novel polypeptide
IT1105131B (it) * 1977-06-08 1985-10-28 Merck & Co Inc Peptidi analoghi della somatostatina dotati di piu' lunga e maggiore attivita' biologica e relativo procedimento di protezione
JPS5850213B2 (ja) * 1977-06-20 1983-11-09 株式会社第一ラジオアイソト−プ研究所 カルチトニンの定量法
JPS62129297A (ja) * 1985-08-09 1987-06-11 Toyo Jozo Co Ltd カルシトニン遺伝子関連ペプチド誘導体
US4658014A (en) * 1985-12-20 1987-04-14 Kempe Tomas G Synthetic peptides with calcitonin-like activity
FR2592049B1 (fr) * 1985-12-24 1988-02-12 Milhaud Gerard Nouveaux analogues de composes polypeptidiques hypocalcemiants epargnant le calcium de l'organisme, leur preparation et les medicaments contenant ces principes actifs
JP2777193B2 (ja) * 1988-10-24 1998-07-16 生化学工業株式会社 ペプチドの製造方法
CA2045495A1 (en) * 1989-11-08 1991-05-09 Masutaka Ohsaki Peptides and processes for producing cyclic peptides

Also Published As

Publication number Publication date
DE69020722T2 (de) 1996-01-18
WO1991007433A1 (en) 1991-05-30
DK0452514T3 (da) 1995-08-21
EP0452514A1 (en) 1991-10-23
EP0452514B1 (en) 1995-07-05
JPH0745517B1 (enExample) 1995-05-17
US5508382A (en) 1996-04-16
EP0452514A4 (en) 1993-04-28
DE69020722D1 (de) 1995-08-10
US5428129A (en) 1995-06-27
KR920701248A (ko) 1992-08-11
JPH0745517B2 (ja) 1995-05-17
CA2045495A1 (en) 1991-05-09

Similar Documents

Publication Publication Date Title
DE69020722D1 (de) Peptide und verfahren zur herstellung von zyklischen peptiden.
EP0722461A4 (en) EXPRESSION OF FUSION POLYPEPTIDES TRANSPORTED OUT OF CYTOPLASM WITHOUT HEAD SEQUENCE
DE3781765D1 (de) Verfahren zur herstellung eines polypeptides.
IL94305A0 (en) Enzymatic removal of a protein amino-terminal sequence
DE69210645D1 (de) Verfahren zur Herstellung von cysteinfreien Peptiden
DE3852074D1 (de) Verfahren zur reinigung von rekombinanten polypeptiden.
DE3586773D1 (de) Verfahren zur beseitigung von n-endaminosaeureresten aus eukaryotpolypeptidanlagen und so erzeugte polypeptide.
HUT63652A (en) Process for producing cd44 surface protein variants, dna sequences encoding them and antibodies against them, as well as their application in diagnosis and therapy
HUT40696A (en) Process for preparing protease resistent urokinase
IL84780A (en) Horse ypsilon-interferon,its preparation,dna sequences encoding it and host organisms containing such sequences
JPS646219A (en) Peptide having promoting action on activation of protein c by thrombin
DE69739013D1 (de) Verfahren zur Herstellung sekretorischer KEX2-Derivate
ES2009588A6 (es) Un metodo para la preparacion de un polipeptido.
PT79013A (de) Verfahren zur herstellung von insulin-derivaten
ATE253639T1 (de) Verfahren zur herstellung von peptiden
EP0330700A4 (en) Human prourokinase-like polypeptide.
DE69013350D1 (de) Von casein-beta ausgehendes verfahren zur herstellung von fraktionen, die mit biologisch aktiven peptiden angereichert sind sowie die so erhaltenen peptidfraktionen.
ATE21118T1 (de) Verfahren zur umwandlung von praeproinsulinanaloga zu insulinen.
CA2025350A1 (en) Process for production of c-terminal .alpha.-amidated peptide
DE58901435D1 (de) Verfahren zur herstellung von dipeptiden mit n-terminalen nichtproteinogenen aminosaeuren.
DE69028935D1 (de) Methode zur Produktion von Glukagon
ATE15209T1 (de) Verfahren zur herstellung von carbonsaeureamidgruppen enthaltenden verbindungen, insbesondere von peptiden.
FR2636643B1 (fr) Peptide-signal, sequences d'adn codant pour celui-ci, vecteurs d'expression portant l'une de ces sequences et procede de production periplasmique d'un polypeptide
EP0572088A3 (en) Changed signal sequences.
ATE127847T1 (de) Verfahren zur herstellung von peptiden.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee