ATE124692T1 - 1,4-benzodioxanderivate, verfahren zu deren herstellung, pharmakologische zusammensetzung und deren verwendung. - Google Patents
1,4-benzodioxanderivate, verfahren zu deren herstellung, pharmakologische zusammensetzung und deren verwendung.Info
- Publication number
- ATE124692T1 ATE124692T1 AT86110080T AT86110080T ATE124692T1 AT E124692 T1 ATE124692 T1 AT E124692T1 AT 86110080 T AT86110080 T AT 86110080T AT 86110080 T AT86110080 T AT 86110080T AT E124692 T1 ATE124692 T1 AT E124692T1
- Authority
- AT
- Austria
- Prior art keywords
- integer
- group
- formula
- chem
- hydrogen atom
- Prior art date
Links
- BNBQRQQYDMDJAH-UHFFFAOYSA-N benzodioxan Chemical class C1=CC=C2OCCOC2=C1 BNBQRQQYDMDJAH-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008196 pharmacological composition Substances 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000031225 myocardial ischemia Diseases 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 230000029865 regulation of blood pressure Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60161096A JPS6222777A (ja) | 1985-07-23 | 1985-07-23 | １，４−ベンゾジオキサン誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE124692T1 true ATE124692T1 (de) | 1995-07-15 |
Family
ID=15728530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86110080T ATE124692T1 (de) | 1985-07-23 | 1986-07-22 | 1,4-benzodioxanderivate, verfahren zu deren herstellung, pharmakologische zusammensetzung und deren verwendung. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US4794118A (en, 2012) |
| EP (2) | EP0307970A1 (en, 2012) |
| JP (1) | JPS6222777A (en, 2012) |
| KR (1) | KR870001189A (en, 2012) |
| AT (1) | ATE124692T1 (en, 2012) |
| AU (1) | AU596108B2 (en, 2012) |
| CA (1) | CA1277321C (en, 2012) |
| DE (1) | DE3650347T2 (en, 2012) |
| DK (1) | DK347486A (en, 2012) |
| ES (2) | ES2004491A6 (en, 2012) |
| HU (1) | HU203230B (en, 2012) |
| NZ (1) | NZ216930A (en, 2012) |
| PH (1) | PH23359A (en, 2012) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63179868A (ja) * | 1987-01-21 | 1988-07-23 | Eisai Co Ltd | １，４−ベンゾジオキサン誘導体及びその製法 |
| US5158956A (en) * | 1990-05-04 | 1992-10-27 | Eli Lilly And Company | Method of inhibiting gastric acid secretion with benzodioxanes |
| CA2438641A1 (en) | 2001-02-15 | 2002-08-22 | King Pharmaceuticals, Inc. | Stabilized pharmaceutical and thyroid hormone compositions and method of preparation |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3101345A (en) * | 1960-04-29 | 1963-08-20 | Thomae Gmbh Dr K | 2-hydroxymethyl-8-hydroxy-1,4-benzodioxane |
| US3166573A (en) * | 1963-11-08 | 1965-01-19 | Colgate Palmolive Co | 2-(nitratoalkyl)-1, 4-benzodioxanes |
-
1985
- 1985-07-23 JP JP60161096A patent/JPS6222777A/ja active Granted
-
1986
- 1986-07-18 US US06/887,720 patent/US4794118A/en not_active Expired - Fee Related
- 1986-07-21 HU HU862980A patent/HU203230B/hu not_active IP Right Cessation
- 1986-07-22 EP EP88116669A patent/EP0307970A1/en not_active Ceased
- 1986-07-22 ES ES8600473A patent/ES2004491A6/es not_active Expired
- 1986-07-22 CA CA000514414A patent/CA1277321C/en not_active Expired - Fee Related
- 1986-07-22 AU AU60424/86A patent/AU596108B2/en not_active Ceased
- 1986-07-22 KR KR1019860005935A patent/KR870001189A/ko not_active Withdrawn
- 1986-07-22 NZ NZ216930A patent/NZ216930A/xx unknown
- 1986-07-22 PH PH34049A patent/PH23359A/en unknown
- 1986-07-22 EP EP86110080A patent/EP0210581B1/en not_active Expired - Lifetime
- 1986-07-22 DK DK347486A patent/DK347486A/da not_active Application Discontinuation
- 1986-07-22 DE DE3650347T patent/DE3650347T2/de not_active Expired - Fee Related
- 1986-07-22 AT AT86110080T patent/ATE124692T1/de not_active IP Right Cessation
-
1988
- 1988-02-01 ES ES8800276A patent/ES2006545A6/es not_active Expired
- 1988-10-04 US US07/253,023 patent/US4959376A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6222777A (ja) | 1987-01-30 |
| DK347486A (da) | 1987-01-24 |
| ES2004491A6 (es) | 1989-01-16 |
| US4794118A (en) | 1988-12-27 |
| HU203230B (en) | 1991-06-28 |
| DK347486D0 (da) | 1986-07-22 |
| US4959376A (en) | 1990-09-25 |
| KR870001189A (ko) | 1987-03-12 |
| DE3650347D1 (de) | 1995-08-10 |
| EP0210581A1 (en) | 1987-02-04 |
| EP0307970A1 (en) | 1989-03-22 |
| EP0210581B1 (en) | 1995-07-05 |
| NZ216930A (en) | 1989-08-29 |
| ES2006545A6 (es) | 1989-05-01 |
| CA1277321C (en) | 1990-12-04 |
| PH23359A (en) | 1989-07-14 |
| AU6042486A (en) | 1987-01-29 |
| JPH0535150B2 (en, 2012) | 1993-05-25 |
| DE3650347T2 (de) | 1996-01-25 |
| AU596108B2 (en) | 1990-04-26 |
| HUT44776A (en) | 1988-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |