ATE123061T1 - Wachstumsregler zusammenhängend mit blutplättchen. - Google Patents
Wachstumsregler zusammenhängend mit blutplättchen.Info
- Publication number
- ATE123061T1 ATE123061T1 AT88301774T AT88301774T ATE123061T1 AT E123061 T1 ATE123061 T1 AT E123061T1 AT 88301774 T AT88301774 T AT 88301774T AT 88301774 T AT88301774 T AT 88301774T AT E123061 T1 ATE123061 T1 AT E123061T1
- Authority
- AT
- Austria
- Prior art keywords
- growth regulators
- blood plates
- regulators related
- polypeptide
- src
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/73—Expression systems using phage (lambda) regulatory sequences
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2060987A | 1987-03-02 | 1987-03-02 | |
US11513987A | 1987-10-30 | 1987-10-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE123061T1 true ATE123061T1 (de) | 1995-06-15 |
Family
ID=26693642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88301774T ATE123061T1 (de) | 1987-03-02 | 1988-03-01 | Wachstumsregler zusammenhängend mit blutplättchen. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0281363B1 (de) |
JP (1) | JPH01503513A (de) |
KR (1) | KR890700672A (de) |
AT (1) | ATE123061T1 (de) |
AU (1) | AU623589B2 (de) |
DE (1) | DE3853842T2 (de) |
ES (1) | ES2074049T3 (de) |
FI (1) | FI100336B (de) |
GR (1) | GR3017041T3 (de) |
IE (1) | IE69678B1 (de) |
IL (1) | IL85613A (de) |
NZ (1) | NZ223696A (de) |
PT (1) | PT86885B (de) |
WO (1) | WO1988006628A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4844895A (en) * | 1985-11-01 | 1989-07-04 | New York University | Composition containing a peptide fragment of platelet factor four and method for restoring suppressed immune responses |
US5026639A (en) * | 1988-01-14 | 1991-06-25 | Nippon Mining Company, Limited | Method to improve mRNA translation and use thereof for production of platelet factor-4 |
GB2214508A (en) * | 1988-01-27 | 1989-09-06 | Bayer Ag | Plasmid vector for the efficient expression of foreign genes fused with newly conceived transcriptional and translational signal sequences. |
US5800820A (en) * | 1989-01-10 | 1998-09-01 | Repligen Corporation | Methods and compositions for treatment of angiogenic diseases |
US5086164A (en) * | 1989-01-10 | 1992-02-04 | Repligen Corporation | Novel methods and compositions for treatment of angiogenic diseases |
US5187075A (en) * | 1989-01-26 | 1993-02-16 | Sri International | Cloning and expression of a variant gene of platelet factor 4 and compositions thereof to modulate immune responses |
US5112946A (en) * | 1989-07-06 | 1992-05-12 | Repligen Corporation | Modified pf4 compositions and methods of use |
CA2113206A1 (en) * | 1991-07-15 | 1993-02-04 | Theodore E. Maione | Modified pf4 compositions and methods of use |
AU3592593A (en) * | 1992-01-16 | 1993-08-03 | Repligen Corporation | Novel methods and compositions for treatment of angiogenic diseases |
WO1995012414A1 (en) * | 1993-11-05 | 1995-05-11 | Repligen Corporation | Novel modified pf4 compositions and methods of use |
IL113561A0 (en) * | 1994-05-09 | 1995-08-31 | Lilly Co Eli | Expression of recombinant mpf-4, cpf-4, pf-4 and precursor compounds |
US5985543A (en) * | 1996-10-11 | 1999-11-16 | The Trustees Of The University Of Pennsylvania | Compositions and methods for detection of antibody binding to cells |
US7067117B1 (en) | 1997-09-11 | 2006-06-27 | Cambridge University Technical Services, Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
US6989435B2 (en) | 1997-09-11 | 2006-01-24 | Cambridge University Technical Services Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
US7238711B1 (en) | 1999-03-17 | 2007-07-03 | Cambridge University Technical Services Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
WO2007053952A1 (en) * | 2005-11-10 | 2007-05-18 | Chemokine Therapeutics Corporation | Platelet factor-4 (pf-4) analogs and their use |
NZ527590A (en) | 2001-03-09 | 2005-12-23 | Genentech Inc | Process for production of polypeptides |
US8609621B2 (en) | 2010-11-15 | 2013-12-17 | E I Du Pont De Nemours And Company | Acid-cleavable linkers exhibiting altered rates of acid hydrolysis |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4565785A (en) * | 1978-06-08 | 1986-01-21 | The President And Fellows Of Harvard College | Recombinant DNA molecule |
IL60184A (en) * | 1979-05-31 | 1984-05-31 | Schering Ag | Process for the specific cleavage of protein sequences from proteins |
US4530901A (en) * | 1980-01-08 | 1985-07-23 | Biogen N.V. | Recombinant DNA molecules and their use in producing human interferon-like polypeptides |
US4582800A (en) * | 1982-07-12 | 1986-04-15 | Hoffmann-La Roche Inc. | Novel vectors and method for controlling interferon expression |
SE8300693L (sv) * | 1983-02-09 | 1984-08-10 | Sven Lofdahl | Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta |
EP0133123A1 (de) * | 1983-07-25 | 1985-02-13 | Mgi Pharma, Inc. | Papillomavirus-Immunogene |
US4645828A (en) * | 1984-03-23 | 1987-02-24 | Oncogen | Platelet related growth regulator |
WO1986001828A1 (en) * | 1984-09-18 | 1986-03-27 | Sagami Chemical Research Center | Cyclic double-stranded dna, process for its preparation, microorganism containing said cyclic double-stranded dna, and process for preparing protein containing antigen determinant site of poliovirus capside protein vp1 using the same |
JPH0816063B2 (ja) * | 1985-03-15 | 1996-02-21 | オンコゲン | 腫瘍細胞増殖阻害剤 |
EP0196864A3 (de) * | 1985-03-25 | 1988-03-23 | Cetus Corporation | Behandlung und Sekretion von rekombinanten Proteinen mittels alkalischer Phosphatase, dazu verwendbare DNA-Sequenzen und mittels dieser Sequenzen transformierte Zellen |
JPS61280292A (ja) * | 1985-06-04 | 1986-12-10 | Wakunaga Pharmaceut Co Ltd | 菌体外分泌による蛋白質の製造法 |
-
1988
- 1988-02-26 AU AU14924/88A patent/AU623589B2/en not_active Ceased
- 1988-02-26 WO PCT/US1988/000634 patent/WO1988006628A1/en active IP Right Grant
- 1988-02-26 JP JP63502722A patent/JPH01503513A/ja active Pending
- 1988-03-01 DE DE3853842T patent/DE3853842T2/de not_active Expired - Fee Related
- 1988-03-01 NZ NZ223696A patent/NZ223696A/en unknown
- 1988-03-01 ES ES88301774T patent/ES2074049T3/es not_active Expired - Lifetime
- 1988-03-01 AT AT88301774T patent/ATE123061T1/de not_active IP Right Cessation
- 1988-03-01 EP EP88301774A patent/EP0281363B1/de not_active Expired - Lifetime
- 1988-03-02 PT PT86885A patent/PT86885B/pt not_active IP Right Cessation
- 1988-03-02 IE IE59188A patent/IE69678B1/en not_active IP Right Cessation
- 1988-03-02 IL IL8561388A patent/IL85613A/en not_active IP Right Cessation
- 1988-11-01 FI FI885031A patent/FI100336B/fi not_active IP Right Cessation
- 1988-11-02 KR KR1019880701398A patent/KR890700672A/ko not_active Application Discontinuation
-
1995
- 1995-08-08 GR GR950402158T patent/GR3017041T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NZ223696A (en) | 1991-06-25 |
KR890700672A (ko) | 1989-04-26 |
IE69678B1 (en) | 1996-10-02 |
PT86885A (pt) | 1989-03-30 |
EP0281363B1 (de) | 1995-05-24 |
IE880591L (en) | 1988-09-02 |
GR3017041T3 (en) | 1995-11-30 |
EP0281363A3 (en) | 1988-11-17 |
EP0281363A2 (de) | 1988-09-07 |
IL85613A (en) | 1994-10-07 |
WO1988006628A1 (en) | 1988-09-07 |
AU1492488A (en) | 1988-09-26 |
ES2074049T3 (es) | 1995-09-01 |
FI885031A (fi) | 1988-11-01 |
FI885031A0 (fi) | 1988-11-01 |
AU623589B2 (en) | 1992-05-21 |
FI100336B (fi) | 1997-11-14 |
JPH01503513A (ja) | 1989-11-30 |
IL85613A0 (en) | 1988-08-31 |
PT86885B (pt) | 1995-08-09 |
DE3853842T2 (de) | 1995-12-07 |
DE3853842D1 (de) | 1995-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |