ATE117318T1 - Aus blaualgen hergestellte biologisch aktive verbindungen. - Google Patents

Aus blaualgen hergestellte biologisch aktive verbindungen.

Info

Publication number
ATE117318T1
ATE117318T1 AT91915762T AT91915762T ATE117318T1 AT E117318 T1 ATE117318 T1 AT E117318T1 AT 91915762 T AT91915762 T AT 91915762T AT 91915762 T AT91915762 T AT 91915762T AT E117318 T1 ATE117318 T1 AT E117318T1
Authority
AT
Austria
Prior art keywords
biologically active
active compounds
compounds produced
blue algae
compounds
Prior art date
Application number
AT91915762T
Other languages
English (en)
Inventor
Frank Koehn
Sue S Cross
Ross E Longley
Original Assignee
Harbor Branch Oceanographic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harbor Branch Oceanographic filed Critical Harbor Branch Oceanographic
Application granted granted Critical
Publication of ATE117318T1 publication Critical patent/ATE117318T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT91915762T 1990-08-08 1991-08-05 Aus blaualgen hergestellte biologisch aktive verbindungen. ATE117318T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/564,817 US5091368A (en) 1990-08-08 1990-08-08 Biologically active compounds from blue-green algae

Publications (1)

Publication Number Publication Date
ATE117318T1 true ATE117318T1 (de) 1995-02-15

Family

ID=24256017

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91915762T ATE117318T1 (de) 1990-08-08 1991-08-05 Aus blaualgen hergestellte biologisch aktive verbindungen.

Country Status (10)

Country Link
US (1) US5091368A (de)
EP (1) EP0542891B1 (de)
JP (1) JPH06500319A (de)
AT (1) ATE117318T1 (de)
CA (1) CA2086918C (de)
DE (1) DE69106877T2 (de)
DK (1) DK0542891T3 (de)
ES (1) ES2067948T3 (de)
GR (1) GR3015824T3 (de)
WO (1) WO1992002541A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010009901A1 (en) 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
US5965537A (en) * 1997-03-10 1999-10-12 Basf Aktiengesellschaft Dolastatin 15 derivatives with carbonyl and heterocyclic functionalities at the C-terminus
US5985837A (en) * 1998-07-08 1999-11-16 Basf Aktiengesellschaft Dolastatin 15 derivatives
EP1229934B1 (de) 1999-10-01 2014-03-05 Immunogen, Inc. Zusammensetzungen und verfahren zur behandlung von krebs mittels immunkonjugaten und chemotherapeutischen agenzien
CN114642718B (zh) * 2022-04-12 2023-12-22 兰州大学 一种治疗癌症的药物靶标及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4548814A (en) * 1980-12-18 1985-10-22 The Board Of Trustees Of The University Of Illinois Composition of matter and process
US4342751A (en) * 1981-03-09 1982-08-03 Eli Lilly And Company Majusculamide C
US4921873A (en) * 1984-12-17 1990-05-01 Harbor Branch Oceanographic Institution, Inc. Antiviral and antitumor cyclohexadienone compositions
US4729996A (en) * 1986-05-29 1988-03-08 Harbor Branch Oceanographic Institution, Inc. Antitumor compositions and their methods of use
US4737510A (en) * 1986-09-30 1988-04-12 The Board Of Trustees Of The University Of Illinois Bioactive metabolites from the caribbean sponge agelas coniferin
US4808590A (en) * 1987-07-17 1989-02-28 Harbor Branch Oceanographic Institution, Inc. Antiviral, antitumor and antifungal compositions and their methods of use
US4970226A (en) * 1989-10-03 1990-11-13 Harbor Branch Oceanographic Institution, Inc. Bis-indole imidazole compounds which are useful antitumor and antimicrobial agents

Also Published As

Publication number Publication date
JPH06500319A (ja) 1994-01-13
WO1992002541A1 (en) 1992-02-20
GR3015824T3 (en) 1995-07-31
EP0542891B1 (de) 1995-01-18
CA2086918A1 (en) 1992-02-09
ES2067948T3 (es) 1995-04-01
DE69106877D1 (de) 1995-03-02
DK0542891T3 (da) 1995-06-12
US5091368A (en) 1992-02-25
CA2086918C (en) 2001-01-02
EP0542891A1 (de) 1993-05-26
DE69106877T2 (de) 1995-05-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee