ATE116292T1 - Synthese von 1-alpha-hydroxy- secosterinverbindungen. - Google Patents

Synthese von 1-alpha-hydroxy- secosterinverbindungen.

Info

Publication number
ATE116292T1
ATE116292T1 AT92302077T AT92302077T ATE116292T1 AT E116292 T1 ATE116292 T1 AT E116292T1 AT 92302077 T AT92302077 T AT 92302077T AT 92302077 T AT92302077 T AT 92302077T AT E116292 T1 ATE116292 T1 AT E116292T1
Authority
AT
Austria
Prior art keywords
alpha
hydroxy
synthesis
secosterol
compounds
Prior art date
Application number
AT92302077T
Other languages
English (en)
Inventor
Hector F Deluca
Heinrich K Schnoes
Kato L Perlman
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/667,440 external-priority patent/US5089641A/en
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Application granted granted Critical
Publication of ATE116292T1 publication Critical patent/ATE116292T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT92302077T 1991-03-11 1992-03-11 Synthese von 1-alpha-hydroxy- secosterinverbindungen. ATE116292T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/667,440 US5089641A (en) 1991-03-11 1991-03-11 Synthesis of 1α-hydroxy-secosterol compounds
US83701092A 1992-02-14 1992-02-14

Publications (1)

Publication Number Publication Date
ATE116292T1 true ATE116292T1 (de) 1995-01-15

Family

ID=27099682

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92302077T ATE116292T1 (de) 1991-03-11 1992-03-11 Synthese von 1-alpha-hydroxy- secosterinverbindungen.

Country Status (6)

Country Link
EP (1) EP0503923B1 (de)
JP (1) JP2793428B2 (de)
AT (1) ATE116292T1 (de)
CA (1) CA2062520C (de)
DE (1) DE69200980T2 (de)
ES (1) ES2065745T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552392A (en) * 1993-11-03 1996-09-03 Wisconsin Alumni Research Foundation Method of treating hypoparathyroidism with (20S) vitamin D compounds
US5763234A (en) * 1996-07-25 1998-06-09 Florida Atlantic University Secosteroids, and method for producing same
EP1828115A4 (de) * 2004-11-22 2010-05-05 Wisconsin Alumni Res Found 2-methylen-19-nor-(20s)-1alpha-hydroxytrishomopregnacalciferol
US8604008B2 (en) 2004-11-22 2013-12-10 Wisconsin Alumni Research Foundation 2-methylene-19,21-dinor-1α-hydroxy-bishomopregnacalciferol
AU2005309818A1 (en) 2004-11-22 2006-06-01 Wisconsin Alumni Research Foundation 2-methylene-19-nor-(20R)-1-alpha-hydroxy-bishomopregnacalciferol

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078704B1 (de) * 1981-11-02 1987-04-29 Research Institute For Medicine And Chemistry Inc. Zwischenprodukte in der Synthese von Vitamin D Derivaten
EP0154185B1 (de) * 1984-02-08 1988-10-05 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Calciferolderivate
IE58473B1 (en) * 1985-04-23 1993-09-22 Wisconsin Alumni Res Found Seco-sterol compounds effective in inducing the differentiation of malignant cells
JP2642189B2 (ja) * 1989-03-23 1997-08-20 株式会社クラレ ステロイド誘導体及びその製造方法
ES2062299T3 (es) * 1989-06-15 1994-12-16 Duphar Int Res Aldehido aducto y su uso para la preparacion de un compuesto de vitamina d.
GB8914963D0 (en) * 1989-06-29 1989-08-23 Leo Pharm Prod Ltd Chemical compounds
GB9017890D0 (en) * 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i

Also Published As

Publication number Publication date
DE69200980T2 (de) 1995-05-11
JP2793428B2 (ja) 1998-09-03
CA2062520A1 (en) 1992-09-12
JPH0597796A (ja) 1993-04-20
ES2065745T3 (es) 1995-02-16
EP0503923A1 (de) 1992-09-16
EP0503923B1 (de) 1994-12-28
DE69200980D1 (de) 1995-02-09
CA2062520C (en) 1998-08-11

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