ATE11409T1 - N-cyclopropylmethyl-14-ethoxymorphinan-6-onverbindungen, die eine gemischte antagonistische analgetisch/narkotische aktivitaet aufweisen, und vorprodukte dafuer. - Google Patents

N-cyclopropylmethyl-14-ethoxymorphinan-6-onverbindungen, die eine gemischte antagonistische analgetisch/narkotische aktivitaet aufweisen, und vorprodukte dafuer.

Info

Publication number
ATE11409T1
ATE11409T1 AT82105422T AT82105422T ATE11409T1 AT E11409 T1 ATE11409 T1 AT E11409T1 AT 82105422 T AT82105422 T AT 82105422T AT 82105422 T AT82105422 T AT 82105422T AT E11409 T1 ATE11409 T1 AT E11409T1
Authority
AT
Austria
Prior art keywords
ethoxymorphinan
preparators
cyclopropylmethyl
compounds exhibiting
antagonist analgesic
Prior art date
Application number
AT82105422T
Other languages
English (en)
Inventor
Anil Chandra Ghosh
Raj Kumar Razdan
Original Assignee
Miles Laboratories, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories, Inc. filed Critical Miles Laboratories, Inc.
Application granted granted Critical
Publication of ATE11409T1 publication Critical patent/ATE11409T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
AT82105422T 1981-06-29 1982-06-21 N-cyclopropylmethyl-14-ethoxymorphinan-6-onverbindungen, die eine gemischte antagonistische analgetisch/narkotische aktivitaet aufweisen, und vorprodukte dafuer. ATE11409T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/278,759 US4362733A (en) 1981-06-29 1981-06-29 N-Cyclopropylmethyl-14-ethoxymorphinan-6-one compounds exhibiting mixed analgesic/narcotic antagonist activity and precursors therefore
EP82105422A EP0068382B1 (de) 1981-06-29 1982-06-21 N-Cyclopropylmethyl-14-ethoxymorphinan-6-on-Verbindungen, die eine gemischte antagonistische analgetisch/narkotische Aktivität aufweisen, und Vorprodukte dafür

Publications (1)

Publication Number Publication Date
ATE11409T1 true ATE11409T1 (de) 1985-02-15

Family

ID=23066237

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82105422T ATE11409T1 (de) 1981-06-29 1982-06-21 N-cyclopropylmethyl-14-ethoxymorphinan-6-onverbindungen, die eine gemischte antagonistische analgetisch/narkotische aktivitaet aufweisen, und vorprodukte dafuer.

Country Status (6)

Country Link
US (1) US4362733A (de)
EP (1) EP0068382B1 (de)
JP (1) JPS588068A (de)
AT (1) ATE11409T1 (de)
CA (1) CA1170654A (de)
DE (1) DE3262036D1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH081711B2 (ja) * 1988-03-29 1996-01-10 松下電器産業株式会社 テープ移送装置
JP6159417B2 (ja) 2012-12-28 2017-07-05 パーデュー、ファーマ、リミテッド、パートナーシップ 置換モルフィナンおよびその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654280A (en) * 1968-03-21 1972-04-04 Shionogi & Co L-n allylic-3-hydroxy-6-oxomorphinans
US4272540A (en) * 1979-04-24 1981-06-09 Sisa, Incorporated 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them
US4260617A (en) * 1979-12-17 1981-04-07 Sisa, Incorporated 17-Cyclopropylmethyl-14-hydroxy-3-methoxymorphinan-6-one and method of treating pain with it

Also Published As

Publication number Publication date
DE3262036D1 (en) 1985-03-07
EP0068382A1 (de) 1983-01-05
CA1170654A (en) 1984-07-10
JPS588068A (ja) 1983-01-18
US4362733A (en) 1982-12-07
EP0068382B1 (de) 1985-01-23

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Legal Events

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UEP Publication of translation of european patent specification
UEP Publication of translation of european patent specification