ATE111515T1 - Drehfilter zur entfernung von weitgehend zellfreiem kulturmedium aus einem suspensionszellkultursystem. - Google Patents
Drehfilter zur entfernung von weitgehend zellfreiem kulturmedium aus einem suspensionszellkultursystem.Info
- Publication number
- ATE111515T1 ATE111515T1 AT90905995T AT90905995T ATE111515T1 AT E111515 T1 ATE111515 T1 AT E111515T1 AT 90905995 T AT90905995 T AT 90905995T AT 90905995 T AT90905995 T AT 90905995T AT E111515 T1 ATE111515 T1 AT E111515T1
- Authority
- AT
- Austria
- Prior art keywords
- cell
- removal
- filter
- rotary filter
- largely
- Prior art date
Links
- 238000004113 cell culture Methods 0.000 title 1
- 239000001963 growth medium Substances 0.000 title 1
- 239000000725 suspension Substances 0.000 title 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- 238000004114 suspension culture Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/18—Flow directing inserts
- C12M27/20—Baffles; Ribs; Ribbons; Auger vanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/813—Continuous fermentation
Landscapes
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/325,286 US5019512A (en) | 1989-03-17 | 1989-03-17 | Spin filter for removing substantially cell-free culture medium from suspension cell culture system |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE111515T1 true ATE111515T1 (de) | 1994-09-15 |
Family
ID=23267235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90905995T ATE111515T1 (de) | 1989-03-17 | 1990-03-15 | Drehfilter zur entfernung von weitgehend zellfreiem kulturmedium aus einem suspensionszellkultursystem. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5019512A (de) |
EP (1) | EP0414887B1 (de) |
JP (1) | JP3030516B2 (de) |
AT (1) | ATE111515T1 (de) |
CA (1) | CA2012321C (de) |
DE (1) | DE69012489T2 (de) |
DK (1) | DK0414887T3 (de) |
ES (1) | ES2065526T3 (de) |
WO (1) | WO1990011345A1 (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
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US5143627A (en) * | 1990-07-09 | 1992-09-01 | Cytyc Corporation | Method and apparatus for preparing cells for examination |
US5282978A (en) * | 1990-07-09 | 1994-02-01 | Cytyc Corporation | Specimen processor method and apparatus |
US5269918A (en) * | 1990-07-09 | 1993-12-14 | Cytyc Corporation | Clinical cartridge apparatus |
US5240606A (en) * | 1990-07-09 | 1993-08-31 | Cytyc Corporation | Apparatus for preparing cells for examination |
US5126269A (en) * | 1990-09-13 | 1992-06-30 | Life Techologies, Inc. | Spin filter perfusion bioreactor (sfpb) cell culture apparatus |
AT394576B (de) * | 1991-01-16 | 1992-05-11 | Vogelbusch Gmbh | Reaktor zur durchfuehrung biologischer reaktionen mittels biokatalysatoren |
US5246671A (en) * | 1991-04-15 | 1993-09-21 | The United States Of America As Represented By The Secretary Of The Army | Reactor |
WO1994017178A1 (en) * | 1993-01-29 | 1994-08-04 | New Brunswick Scientific Co., Inc. | Method and apparatus for anchorage and suspension cell culture |
DE19918409A1 (de) * | 1999-04-22 | 2000-10-26 | Forschungszentrum Juelich Gmbh | Bioreaktor umfassend einen Medienablauf und einen Rührer sowie Rührer und Medienablauf |
AU2002363076A1 (en) * | 2001-10-26 | 2003-05-06 | Virtual Arrays, Inc. | Assay systems with adjustable fluid communication |
US20080187949A1 (en) * | 2001-10-26 | 2008-08-07 | Millipore Corporation | Multiplexed assays of cell migration |
US20040126773A1 (en) * | 2002-05-23 | 2004-07-01 | Beske Oren E. | Assays with coded sensor particles to sense assay conditions |
US20080207465A1 (en) * | 2002-10-28 | 2008-08-28 | Millipore Corporation | Assay systems with adjustable fluid communication |
US20040124140A1 (en) * | 2002-12-30 | 2004-07-01 | Sawyer Gary A. | In situ filtration draught tube reactor system |
US20040259240A1 (en) * | 2003-06-17 | 2004-12-23 | Fadden Stephen J. | Method and apparatus for filtration of bioreactor recombinant proteins |
US20050095700A1 (en) * | 2003-11-03 | 2005-05-05 | Thomas Budzowski | Method for maintaining low shear in a bioprocessing system |
JP2007525984A (ja) * | 2004-03-05 | 2007-09-13 | ディーエスエム アイピー アセッツ ビー.ブイ. | 連続的灌流および交互接線流による細胞培養の方法 |
SI2041259T1 (sl) | 2006-07-14 | 2016-04-29 | Dpx Holdings B.V. | Izboljšan postopek kultiviranja celic |
KR100834110B1 (ko) * | 2007-01-25 | 2008-06-02 | 한국과학기술원 | 상류 충전탑 세포재순환 장치가 장착된 다단계 cstr생물반응기 시스템 |
CN101085978B (zh) * | 2007-06-27 | 2011-01-05 | 广州铭康生物工程有限公司 | 一种用于动物细胞灌流培养的过滤-沉降双结合灌流系统 |
KR100893875B1 (ko) | 2007-09-11 | 2009-04-20 | 박중진 | 여과통 회전 탈수식 배양기 |
US20100112696A1 (en) * | 2008-11-03 | 2010-05-06 | Baxter International Inc. | Apparatus And Methods For Processing Tissue To Release Cells |
US8309343B2 (en) | 2008-12-01 | 2012-11-13 | Baxter International Inc. | Apparatus and method for processing biological material |
US8580554B2 (en) | 2009-07-31 | 2013-11-12 | Baxter International Inc. | Method of producing a polypeptide or virus of interest in a continuous cell culture |
US20110117538A1 (en) * | 2009-11-13 | 2011-05-19 | Niazi Sarfaraz K | Bioreactors for fermentation and related methods |
US9956236B2 (en) | 2011-02-07 | 2018-05-01 | Cornell University | Methods for increasing immune responses using agents that directly bind to and activate IRE-1 |
US8808990B2 (en) | 2011-05-12 | 2014-08-19 | Exact Sciences Corporation | Serial isolation of multiple DNA targets from stool |
ES2642683T3 (es) | 2011-05-12 | 2017-11-17 | Exact Sciences Corporation | Aislamiento de ácidos nucleicos |
US8993341B2 (en) | 2011-05-12 | 2015-03-31 | Exact Sciences Corporation | Removal of PCR inhibitors |
US20140193900A1 (en) | 2011-06-09 | 2014-07-10 | Ivar Meyvantsson | Device for washing suspended cells or particles |
DK3049521T3 (en) | 2013-09-25 | 2019-04-23 | Univ Cornell | Compounds for inducing antitumor immunity and methods thereof |
WO2016061526A1 (en) | 2014-10-17 | 2016-04-21 | Sani-Tech West, Inc. | Mixing and filtering system and method |
JP6744161B2 (ja) * | 2016-07-19 | 2020-08-19 | 株式会社日立プラントサービス | 分離装置、培養装置および分離方法 |
KR101956304B1 (ko) * | 2016-09-06 | 2019-03-11 | 한국화학연구원 | 세포 배양 용기 |
US10858607B2 (en) * | 2017-05-18 | 2020-12-08 | Active Energy Group Plc | Process for beneficiating and cleaning biomass |
SG11202000986SA (en) | 2017-08-31 | 2020-03-30 | Massachusetts Inst Technology | Hollow fibre membrane filtration systems and methods for manufacturing biologically-produced products |
CN112322458B (zh) * | 2020-11-07 | 2022-03-11 | 河南农业大学 | 一种提振式生物质厌氧装置 |
JP2022093036A (ja) * | 2020-12-11 | 2022-06-23 | 株式会社神鋼環境ソリューション | ろ過装置 |
AU2022210821A1 (en) * | 2021-01-21 | 2023-08-31 | Repairon Gmbh | Method of changing culture medium of a culture using spinfilters |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3186917A (en) * | 1962-04-18 | 1965-06-01 | Biochemical Processes Inc | Process and apparatus for dialysis fermentation |
CH647547A5 (de) * | 1982-02-12 | 1985-01-31 | Chemap Ag | Verfahren und vorrichtung zum zuechten von mikroorganismen. |
FR2527799B1 (fr) * | 1982-05-28 | 1986-05-23 | Thomson Csf | Dispositif de mise en memoire d'une image coherente dans une cavite optique multimode |
DE3402697A1 (de) * | 1984-01-26 | 1985-08-01 | Bayer Ag, 5090 Leverkusen | Verwendung von hydrophilen, hochgefuellten polyurethanmassen zur biologischen abwasserreinigung |
US4649118A (en) * | 1984-04-05 | 1987-03-10 | The Virtis Company, Inc. | Cell culturing apparatus with improved stirring and filter means |
JPS60259179A (ja) * | 1984-06-05 | 1985-12-21 | Teijin Ltd | 細胞培養槽及び細胞培養方法 |
SU1296575A1 (ru) * | 1984-12-10 | 1987-03-15 | Предприятие П/Я Р-6729 | Аппарат дл культивировани клеток |
JPS62265A (ja) * | 1985-02-05 | 1987-01-06 | Teijin Ltd | 細胞培養装置および方法 |
US4639422A (en) * | 1986-02-03 | 1987-01-27 | Monsanto Company | Cell culture filter apparatus and method |
US4921792A (en) * | 1987-11-27 | 1990-05-01 | Miles Inc. | Continuous cell dispersion, cultivation and substance recovery process |
US4988623A (en) * | 1988-06-30 | 1991-01-29 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Rotating bio-reactor cell culture apparatus |
-
1989
- 1989-03-17 US US07/325,286 patent/US5019512A/en not_active Expired - Lifetime
-
1990
- 1990-03-15 JP JP2505691A patent/JP3030516B2/ja not_active Expired - Fee Related
- 1990-03-15 DK DK90905995.8T patent/DK0414887T3/da active
- 1990-03-15 EP EP90905995A patent/EP0414887B1/de not_active Expired - Lifetime
- 1990-03-15 WO PCT/US1990/001357 patent/WO1990011345A1/en active IP Right Grant
- 1990-03-15 DE DE69012489T patent/DE69012489T2/de not_active Expired - Fee Related
- 1990-03-15 ES ES90905995T patent/ES2065526T3/es not_active Expired - Lifetime
- 1990-03-15 AT AT90905995T patent/ATE111515T1/de not_active IP Right Cessation
- 1990-03-15 CA CA002012321A patent/CA2012321C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0414887A1 (de) | 1991-03-06 |
EP0414887A4 (en) | 1991-09-11 |
DK0414887T3 (da) | 1994-11-14 |
DE69012489T2 (de) | 1995-02-02 |
EP0414887B1 (de) | 1994-09-14 |
CA2012321A1 (en) | 1990-09-17 |
US5019512A (en) | 1991-05-28 |
ES2065526T3 (es) | 1995-02-16 |
JPH03505041A (ja) | 1991-11-07 |
CA2012321C (en) | 2004-05-18 |
DE69012489D1 (de) | 1994-10-20 |
WO1990011345A1 (en) | 1990-10-04 |
JP3030516B2 (ja) | 2000-04-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |