ATE107635T1 - Arylendiamin-substituierte pyrimidine. - Google Patents
Arylendiamin-substituierte pyrimidine.Info
- Publication number
- ATE107635T1 ATE107635T1 AT89308739T AT89308739T ATE107635T1 AT E107635 T1 ATE107635 T1 AT E107635T1 AT 89308739 T AT89308739 T AT 89308739T AT 89308739 T AT89308739 T AT 89308739T AT E107635 T1 ATE107635 T1 AT E107635T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted pyrimidines
- arylenediamine
- substituents
- alkyl
- compounds
- Prior art date
Links
- 150000003230 pyrimidines Chemical class 0.000 title abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/16—Nitrogen-containing compounds
- C08K5/34—Heterocyclic compounds having nitrogen in the ring
- C08K5/3442—Heterocyclic compounds having nitrogen in the ring having two nitrogen atoms in the ring
- C08K5/3462—Six-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/247,143 US4946956A (en) | 1988-09-21 | 1988-09-21 | Arylenediamine substituted pyrimidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE107635T1 true ATE107635T1 (de) | 1994-07-15 |
Family
ID=22933755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89308739T ATE107635T1 (de) | 1988-09-21 | 1989-08-30 | Arylendiamin-substituierte pyrimidine. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4946956A (de) |
| EP (1) | EP0363002B1 (de) |
| KR (1) | KR0120735B1 (de) |
| AT (1) | ATE107635T1 (de) |
| BR (1) | BR8904702A (de) |
| CA (1) | CA1339846C (de) |
| DE (1) | DE68916359T2 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6632820B1 (en) | 1998-08-29 | 2003-10-14 | Astrazeneca Ab | Pyrimidine compounds |
| ES2274634T3 (es) | 1998-08-29 | 2007-05-16 | Astrazeneca Ab | Compuestos de pirimidina. |
| GB9828511D0 (en) | 1998-12-24 | 1999-02-17 | Zeneca Ltd | Chemical compounds |
| GB9905075D0 (en) | 1999-03-06 | 1999-04-28 | Zeneca Ltd | Chemical compounds |
| GB9907658D0 (en) | 1999-04-06 | 1999-05-26 | Zeneca Ltd | Chemical compounds |
| GB9919778D0 (en) | 1999-08-21 | 1999-10-27 | Zeneca Ltd | Chemical compounds |
| GB0004887D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0004890D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0004888D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0004886D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
| US6465604B2 (en) | 2000-03-21 | 2002-10-15 | Flexsys America L.P. | Pyrimidine derivatives as hardness stabilizers |
| CN1215110C (zh) * | 2000-03-21 | 2005-08-17 | 弗莱克塞斯美国公司 | 作为硬度稳定剂的嘧啶衍生物 |
| GB0007371D0 (en) | 2000-03-28 | 2000-05-17 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0016877D0 (en) | 2000-07-11 | 2000-08-30 | Astrazeneca Ab | Chemical compounds |
| GB0021726D0 (en) | 2000-09-05 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
| US20030078271A1 (en) * | 2001-01-31 | 2003-04-24 | Blackburn Thomas P. | Use of GAL3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods |
| IL157102A0 (en) * | 2001-01-31 | 2004-02-08 | Synaptic Pharma Corp | Use of gal3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods |
| US7081470B2 (en) * | 2001-01-31 | 2006-07-25 | H. Lundbeck A/S | Use of GALR3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods |
| US20040127502A1 (en) * | 2001-01-31 | 2004-07-01 | Synaptic Pharmaceutical Corporation | Use of GAL3 antagonist for treatment of depression |
| GB0103926D0 (en) | 2001-02-17 | 2001-04-04 | Astrazeneca Ab | Chemical compounds |
| GB0113041D0 (en) | 2001-05-30 | 2001-07-18 | Astrazeneca Ab | Chemical compounds |
| AU2003208479A1 (en) | 2002-03-09 | 2003-09-22 | Astrazeneca Ab | 4- imidazolyl substuited pyrimidine derivatives with cdk inhibitiory activity |
| GB0205688D0 (en) | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
| GB0205690D0 (en) | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
| GB0205693D0 (en) | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
| US6936607B2 (en) * | 2002-08-07 | 2005-08-30 | H. Lunobeck A/S | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety |
| GB0311276D0 (en) | 2003-05-16 | 2003-06-18 | Astrazeneca Ab | Chemical compounds |
| GB0311274D0 (en) | 2003-05-16 | 2003-06-18 | Astrazeneca Ab | Chemical compounds |
| TW200528101A (en) | 2004-02-03 | 2005-09-01 | Astrazeneca Ab | Chemical compounds |
| CA2623374A1 (en) | 2005-09-30 | 2007-04-05 | Astrazeneca Ab | Imidazo [1,2-a] pyridine having anti-cell-proliferation activity |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3206398A1 (de) * | 1982-02-23 | 1983-09-01 | Basf Ag, 6700 Ludwigshafen | S-triazinderivate und ihre verwendung als lichtschutzmittel |
| US4650867A (en) * | 1985-03-26 | 1987-03-17 | Ciba-Geigy Corporation | Process for the preparation of 2,4,6-tris(aminophenylamino)triazines |
| US4786672A (en) * | 1986-07-31 | 1988-11-22 | Ciba-Geigy Corporation | Anilinotriazines and the use thereof |
| US4794134A (en) * | 1987-08-28 | 1988-12-27 | Uniroyal Chemical Company, Inc. | Ozone resistant elastomeric articles |
| JPH033982A (ja) * | 1989-05-31 | 1991-01-10 | Matsushita Electric Works Ltd | エアーポンプ |
-
1988
- 1988-09-21 US US07/247,143 patent/US4946956A/en not_active Expired - Lifetime
-
1989
- 1989-08-30 EP EP89308739A patent/EP0363002B1/de not_active Expired - Lifetime
- 1989-08-30 DE DE68916359T patent/DE68916359T2/de not_active Expired - Fee Related
- 1989-08-30 CA CA000609896A patent/CA1339846C/en not_active Expired - Fee Related
- 1989-08-30 AT AT89308739T patent/ATE107635T1/de not_active IP Right Cessation
- 1989-09-19 BR BR898904702A patent/BR8904702A/pt not_active IP Right Cessation
- 1989-09-19 KR KR1019890013422A patent/KR0120735B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE68916359T2 (de) | 1994-10-27 |
| KR0120735B1 (ko) | 1997-10-30 |
| EP0363002A1 (de) | 1990-04-11 |
| CA1339846C (en) | 1998-04-28 |
| BR8904702A (pt) | 1990-05-01 |
| US4946956A (en) | 1990-08-07 |
| EP0363002B1 (de) | 1994-06-22 |
| KR900004700A (ko) | 1990-04-12 |
| DE68916359D1 (de) | 1994-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |