ATE101147T1 - Pharmazeutisch verwendbare polymorphe modifikation von buspiron. - Google Patents

Pharmazeutisch verwendbare polymorphe modifikation von buspiron.

Info

Publication number
ATE101147T1
ATE101147T1 AT88113970T AT88113970T ATE101147T1 AT E101147 T1 ATE101147 T1 AT E101147T1 AT 88113970 T AT88113970 T AT 88113970T AT 88113970 T AT88113970 T AT 88113970T AT E101147 T1 ATE101147 T1 AT E101147T1
Authority
AT
Austria
Prior art keywords
buspiron
pharmaceutically useable
polymorph modification
polymorph
modification
Prior art date
Application number
AT88113970T
Other languages
English (en)
Inventor
Jack C Simms
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22225222&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE101147(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE101147T1 publication Critical patent/ATE101147T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Body Structure For Vehicles (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AT88113970T 1987-08-28 1988-08-26 Pharmazeutisch verwendbare polymorphe modifikation von buspiron. ATE101147T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/090,984 US5015646A (en) 1987-08-28 1987-08-28 Pharmaceutically useful polymorphic modification of buspirone
EP88113970A EP0304941B1 (de) 1987-08-28 1988-08-26 Pharmazeutisch verwendbare polymorphe Modifikation von Buspiron

Publications (1)

Publication Number Publication Date
ATE101147T1 true ATE101147T1 (de) 1994-02-15

Family

ID=22225222

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88113970T ATE101147T1 (de) 1987-08-28 1988-08-26 Pharmazeutisch verwendbare polymorphe modifikation von buspiron.

Country Status (22)

Country Link
US (1) US5015646A (de)
EP (1) EP0304941B1 (de)
JP (1) JP2716740B2 (de)
KR (1) KR970011297B1 (de)
AT (1) ATE101147T1 (de)
AU (1) AU618549B2 (de)
CY (1) CY1785A (de)
DE (1) DE3887598T2 (de)
DK (1) DK170821B1 (de)
ES (1) ES2061576T3 (de)
FI (1) FI883961A7 (de)
HK (1) HK74494A (de)
HU (1) HU201322B (de)
IE (1) IE63071B1 (de)
IL (1) IL87468A (de)
MY (1) MY104061A (de)
NO (1) NO883805D0 (de)
NZ (1) NZ225896A (de)
OA (1) OA08908A (de)
PT (1) PT88356B (de)
YU (1) YU46962B (de)
ZA (1) ZA886082B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810789A (en) * 1987-08-28 1989-03-07 Bristol-Myers Company Process for buspirone hydrochloride polymorphic crystalline form conversion
US5484788A (en) * 1993-03-26 1996-01-16 Beth Israel Hospital Association Buspirone as a systemic immunosuppressant
US5631017A (en) * 1993-03-26 1997-05-20 Beth Israel Deaconess Medical Center, Inc. Topical application of buspirone for treatment of pathological conditions associated with immune responses
HU217129B (hu) * 1993-07-16 1999-11-29 EGIS Gyógyszergyár Rt. Eljárás nagy tisztaságú buspiron gyógyászati hatóanyag előállítására
US5637314A (en) * 1995-06-07 1997-06-10 Beth Israel Deaconess Medical Center, Inc. Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
JP3547707B2 (ja) 1998-06-19 2004-07-28 帝人株式会社 ２−（３−シアノ−４−イソブチルオキシフェニル）−４−メチル−５−チアゾールカルボン酸の結晶多形体およびその製造方法
US6465255B1 (en) * 1999-01-29 2002-10-15 The Regents Of The University Of California Method for identifying and probing phase transitions in materials
KR100433165B1 (ko) * 2000-10-10 2004-05-27 엔앤비텍 주식회사 가공란의 제조 방법, 상기 방법에 의하여 제조된 가공란,및 가공란을 제조하기 위한 장치
CL2004001034A1 (es) 2003-05-14 2005-03-28 Teijin Pharma Ltd Formas cristalinas de acido 4-(1-((,etilbenzotiofen-3-il)me til)benzimidazol-2-iltio)butanoico; procedimiento de preparacion de las formas cristalinas; composicion farmaceutica; y su uso para el tratamiento de enfermedades inflamatorias, alergicas, r
KR101292492B1 (ko) 2004-05-11 2013-08-01 이모셔널 브레인 비.브이. 약제학적 제형물 및 여성 성기능 부전의 치료에서 그것의용도
US20080015240A1 (en) * 2004-11-12 2008-01-17 Mitsuru Teramoto Acid Salt of Benzimidazole Derivative and Crystal Thereof
EP1790343A1 (de) 2005-11-11 2007-05-30 Emotional Brain B.V. Pharmazeutische Zusammensetzungen und deren Verwendung zur Behandlung sexueller Störungen der Frau
EP1925307A1 (de) * 2006-11-03 2008-05-28 Emotional Brain B.V. Verwendung von 3-alpha-androstanediol zur Behandlung sexueller Dysfunktion
CN118702676B (zh) * 2024-07-09 2026-01-27 济南大学 一种盐酸丁螺环酮晶型ii的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
US4351939A (en) * 1980-10-16 1982-09-28 Mead Johnson & Company Spiro-quaternary ammonium halides and N-(2-pyrimidinyl)piperazinylalkylazaspiroalkanedione process
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen

Also Published As

Publication number Publication date
EP0304941B1 (de) 1994-02-02
FI883961L (fi) 1989-03-01
NZ225896A (en) 1991-04-26
ZA886082B (en) 1989-04-26
US5015646A (en) 1991-05-14
AU2107688A (en) 1989-03-02
JP2716740B2 (ja) 1998-02-18
DE3887598D1 (de) 1994-03-17
HK74494A (en) 1994-08-05
FI883961A7 (fi) 1989-03-01
KR890003740A (ko) 1989-04-17
IE882528L (en) 1989-02-28
IL87468A0 (en) 1989-01-31
JPS6471816A (en) 1989-03-16
YU161688A (en) 1990-10-31
AU618549B2 (en) 1992-01-02
MY104061A (en) 1993-11-30
ES2061576T3 (es) 1994-12-16
CY1785A (en) 1995-10-20
DK478788D0 (da) 1988-08-26
IE63071B1 (en) 1995-03-22
PT88356A (pt) 1989-06-30
IL87468A (en) 1992-12-01
HU201322B (en) 1990-10-28
DK478788A (da) 1989-03-01
FI883961A0 (fi) 1988-08-26
EP0304941A1 (de) 1989-03-01
KR970011297B1 (ko) 1997-07-09
DK170821B1 (da) 1996-01-29
NO883805D0 (no) 1988-08-25
PT88356B (pt) 1995-03-31
HUT47564A (en) 1989-03-28
YU46962B (sh) 1994-09-09
OA08908A (en) 1989-10-31
DE3887598T2 (de) 1994-05-19

Similar Documents

Publication Publication Date Title
ATE101147T1 (de) Pharmazeutisch verwendbare polymorphe modifikation von buspiron.
PH31123A (en) Benzimidazole compounds.
ES2132284T3 (es) Derivados de carbamato de 2-(piperidin-4-il, piridin-4-il y tetrahidropiridin-4-il)-benzofurano-7, su preparacion y su uso como inhibidores de acetilcolinesterasa.
NO964859D0 (no) Fremgangsmåte for fremstilling av vannfrie og hydratformer av antihistaminiske piperidinderivater, polymorfer og pseudomorfer derav
DE68914292D1 (de) Zusammensetzung zur Behandlung von ischämischen Störungen in Organen.
ATE88894T1 (de) Methode zur behandlung von kachexie und bestimmte dafuer anzuwendende verbindungen.
ATE152711T1 (de) Substituierte chinolincarboxylsäure
ES8702403A1 (es) Un procedimiento para la preparacion de nuevas n-((4-piperidinil)alquil)oxazol y tiazolaminas condensadas biciclicas sustituidas
DE69104314D1 (de) Verwendung von 1-[3-(Dimethylamino)propyl]-1-phenylphthalenen zur Behandlung zerebrovaskulärer Störungen.
SE8305467L (sv) 1,4-dihydropyridinderivat
PT88656A (pt) Process for preparing 4-aminopyridine derivatives
ATE113044T1 (de) Verfahren zur umwandlung des niedrigschmelzenden polymorphs von buspirone hydrochlorid in das höherschmelzende.
RO92245A (ro) Procedeu pentru prepararea unor derivati de 1,6-naftiridina
FI893682A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten 1,2,5-ditiatsosiinijohdannaisten valmistamiseksi
DE3889772D1 (de) Verfahren zur Herstellung von 3,3-Diarylacrylsäureamiden.
ES557207A0 (es) Un procedimiento para preparar benzo(c)-1,5-naftiridinas
PL291408A1 (en) Method of obtaining novel 1-(pyridinylalkylo)-1h-indoles
ES2085540T3 (es) 2-(3-fenilpropil)hidrazinas, productos intermedios en y un procedimiento para la preparacion de las mismas, y su uso como medicamentos.
PT98646A (pt) Processo para a preparacao de carbamoil-1-(piridinalquil)-1h-indois indolinas e os seus analogos

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee