ATA677577A - METHOD FOR PRODUCING NEW SUBSTITUTED 6-PHENYL-1,2,4-TRIAZOLO- (4,3-B) PYRI- DACINS AND THE SALTS THEREOF - Google Patents
METHOD FOR PRODUCING NEW SUBSTITUTED 6-PHENYL-1,2,4-TRIAZOLO- (4,3-B) PYRI- DACINS AND THE SALTS THEREOFInfo
- Publication number
- ATA677577A ATA677577A AT677577A AT677577A ATA677577A AT A677577 A ATA677577 A AT A677577A AT 677577 A AT677577 A AT 677577A AT 677577 A AT677577 A AT 677577A AT A677577 A ATA677577 A AT A677577A
- Authority
- AT
- Austria
- Prior art keywords
- dacins
- pyri
- triazolo
- phenyl
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/12—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT652179A AT361495B (en) | 1976-09-22 | 1979-10-05 | PROCESS FOR PRODUCING NEW SUBSTITUTED 6-PHENYL-1,2,4-TRIAZOLO (4,3-B) PYRIDAZINES AND THEIR SALTS |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/725,597 US4230705A (en) | 1976-09-22 | 1976-09-22 | 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazines and their uses in treating anxiety |
| US73039576A | 1976-10-07 | 1976-10-07 | |
| US73547576A | 1976-10-26 | 1976-10-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA677577A true ATA677577A (en) | 1980-05-15 |
| AT360034B AT360034B (en) | 1980-12-10 |
Family
ID=27419081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT677577A AT360034B (en) | 1976-09-22 | 1977-09-21 | METHOD FOR PRODUCING NEW SUBSTITUTED 6-PHENYL-1,2,4-TRIAZOLO- (4,3-B) PYRI- DACINS AND THE SALTS THEREOF |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS5340798A (en) |
| AR (2) | AR218036A1 (en) |
| AT (1) | AT360034B (en) |
| AU (1) | AU513760B2 (en) |
| BG (1) | BG29287A3 (en) |
| CA (1) | CA1080712A (en) |
| DD (1) | DD132586A5 (en) |
| DE (1) | DE2741763A1 (en) |
| DK (1) | DK417377A (en) |
| ES (3) | ES462543A1 (en) |
| FI (1) | FI772802A (en) |
| FR (1) | FR2442848A1 (en) |
| GB (1) | GB1589237A (en) |
| GR (1) | GR71699B (en) |
| LU (1) | LU78150A1 (en) |
| NL (1) | NL7710389A (en) |
| NO (1) | NO773245L (en) |
| PT (1) | PT67067B (en) |
| RO (1) | RO72226A (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR70309B (en) * | 1979-10-29 | 1982-09-08 | Dow Chemical Co | |
| FR2473522A1 (en) * | 1980-01-16 | 1981-07-17 | Synthelabo | NOVEL DIHYDRO-2,3 IMIDAZO (1,2-B) PYRIDAZINE SUBSTITUTED DERIVATIVES AND MEDICAMENTS, PARTICULARLY USEFUL AS ANTIDEPRESSANTS, CONTAINING THEM |
| DE3173083D1 (en) * | 1980-03-22 | 1986-01-16 | Fbc Ltd | Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use |
| DE3217325A1 (en) * | 1982-05-08 | 1983-11-10 | Hoechst Ag, 6230 Frankfurt | 3-AMINO-6-ARYL-1,2,4-TRIAZOLO (4,3-B) -PYRIDAZINE, THEIR PRODUCTION AND USE |
| US4487930A (en) * | 1982-09-07 | 1984-12-11 | The Dow Chemical Company | 6-[(Cyclic amino)alkylamino]-tetrahydrotriazolo[3,4-a]phthalazines |
| FR2562071B1 (en) * | 1984-03-30 | 1986-12-19 | Sanofi Sa | TRIAZOLO (4,3-B) PYRIDAZINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| US4767765A (en) * | 1985-10-31 | 1988-08-30 | American Cyanamid Company | N-substituted-N-[3-(1,2,4-triazolo-[4,3-b]pyridazin-6-yl)phenyl]alkanamides, carbamates and ureas |
| US4654343A (en) * | 1985-10-31 | 1987-03-31 | American Cyanamid Company | N-substituted-N[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]alkanamides, carbamates and ureas |
| CN1251589A (en) * | 1996-07-25 | 2000-04-26 | 默克·夏普-道姆公司 | Substituted triazolo-pyridazine derivatives as ligands for GABA receptors |
| WO1999036423A1 (en) * | 1998-01-14 | 1999-07-22 | Merck Sharp & Dohme Limited | Triazolo-pyridazine derivatives as ligands for gaba receptors |
| GB9801210D0 (en) | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801234D0 (en) * | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GEP20032868B (en) | 1998-01-21 | 2003-01-27 | Merck Sharp & Dohme | Triazolo-Pyridazine Derivatives as Ligands for Gaba Receptors, Methods for Their Production, Pharmaceutical Compositions Containing the Same for Treatment and/or Prevention of disorders of Central Nervous System |
| GB9801202D0 (en) * | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801208D0 (en) * | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801397D0 (en) * | 1998-01-22 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801538D0 (en) | 1998-01-23 | 1998-03-25 | Merck Sharp & Dohme | Pharmaceutical product |
| US7645756B2 (en) * | 2004-02-18 | 2010-01-12 | Banyu Pharmaceutical Co. Ltd. | Nitrogenous fused heteroaromatic ring derivative |
| EP3548033B1 (en) * | 2016-11-28 | 2024-04-10 | Praxis Precision Medicines, Inc. | Compounds and their methods of use |
| MX2020012838A (en) | 2018-05-30 | 2021-07-16 | Praxis Prec Medicines Inc | Ion channel modulators. |
| US11773099B2 (en) | 2019-05-28 | 2023-10-03 | Praxis Precision Medicines, Inc. | Compounds and their methods of use |
| US11505554B2 (en) | 2019-05-31 | 2022-11-22 | Praxis Precision Medicines, Inc. | Substituted pyridines as ion channel modulators |
-
1977
- 1977-08-16 CA CA284,806A patent/CA1080712A/en not_active Expired
- 1977-08-19 GR GR54197A patent/GR71699B/el unknown
- 1977-09-07 AR AR269126A patent/AR218036A1/en active
- 1977-09-16 DE DE19772741763 patent/DE2741763A1/en not_active Withdrawn
- 1977-09-20 LU LU78150A patent/LU78150A1/xx unknown
- 1977-09-20 RO RO7791618A patent/RO72226A/en unknown
- 1977-09-20 BG BG7737371A patent/BG29287A3/en unknown
- 1977-09-21 NO NO773245A patent/NO773245L/en unknown
- 1977-09-21 AU AU28995/77A patent/AU513760B2/en not_active Expired
- 1977-09-21 AT AT677577A patent/AT360034B/en not_active IP Right Cessation
- 1977-09-21 DK DK417377A patent/DK417377A/en unknown
- 1977-09-22 FR FR7728639A patent/FR2442848A1/en active Pending
- 1977-09-22 DD DD7700201157A patent/DD132586A5/en unknown
- 1977-09-22 NL NL7710389A patent/NL7710389A/en not_active Application Discontinuation
- 1977-09-22 ES ES462543A patent/ES462543A1/en not_active Expired
- 1977-09-22 PT PT67067A patent/PT67067B/en unknown
- 1977-09-22 JP JP11344877A patent/JPS5340798A/en active Pending
- 1977-09-22 GB GB39619/77A patent/GB1589237A/en not_active Expired
- 1977-09-22 FI FI772802A patent/FI772802A/en not_active Application Discontinuation
-
1978
- 1978-12-18 AR AR274489A patent/AR217886A1/en active
-
1979
- 1979-02-16 ES ES477799A patent/ES477799A1/en not_active Expired
- 1979-02-16 ES ES477800A patent/ES477800A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT360034B (en) | 1980-12-10 |
| ES462543A1 (en) | 1979-06-16 |
| JPS5340798A (en) | 1978-04-13 |
| LU78150A1 (en) | 1978-01-23 |
| AU2899577A (en) | 1979-03-29 |
| NO773245L (en) | 1978-03-28 |
| RO72226A (en) | 1982-09-09 |
| BG29287A3 (en) | 1980-10-15 |
| ES477799A1 (en) | 1980-04-01 |
| FI772802A (en) | 1978-03-23 |
| DD132586A5 (en) | 1978-10-11 |
| DK417377A (en) | 1978-03-23 |
| GB1589237A (en) | 1981-05-07 |
| CA1080712A (en) | 1980-07-01 |
| AU513760B2 (en) | 1980-12-18 |
| GR71699B (en) | 1983-06-21 |
| PT67067B (en) | 1979-02-19 |
| DE2741763A1 (en) | 1978-03-23 |
| ES477800A1 (en) | 1979-10-16 |
| PT67067A (en) | 1977-10-01 |
| AR218036A1 (en) | 1980-05-15 |
| NL7710389A (en) | 1978-03-28 |
| AR217886A1 (en) | 1980-04-30 |
| FR2442848A1 (en) | 1980-06-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATA800876A (en) | METHOD FOR PRODUCING NEW 2-PHENYL-3-AROYLBENZOTHIOPHENEN AND 2-PHENYL-3- -AROYLBENZOTHIOPHEN-1-OXIDEN AND THE SALTS THEREOF | |
| AT361932B (en) | METHOD FOR PRODUCING NEW PIPERAZINE-1-YL-ACETHYDROXAMIC ACIDS AND THE SALTS THEREOF | |
| AT360034B (en) | METHOD FOR PRODUCING NEW SUBSTITUTED 6-PHENYL-1,2,4-TRIAZOLO- (4,3-B) PYRI- DACINS AND THE SALTS THEREOF | |
| AT361912B (en) | METHOD FOR PRODUCING NEW HETEROCYCLIC 1-ARYLOXY-2-HYDROXY-3-ALKYLENE AMINOPROPANES AND THE SALTS THEREOF | |
| AT363491B (en) | METHOD FOR PRODUCING NEW 1,3,8TRISUBSTITUTED XANTHINS AND THEIR SALTS | |
| AT357553B (en) | METHOD FOR PRODUCING NEW 2- (2,2-DIARYLALKYL) -1-AZABICYCLO (2.2.2) OCTANS AND THEIR SALTS | |
| AT359064B (en) | METHOD FOR PRODUCING NEW 1H- -PYRAZOLO (3,4-B) -PYRIDINES AND THEIR ACID ADDITION SALTS | |
| AT355018B (en) | METHOD FOR PRODUCING NEW 1,2-BENZISOTHIAZOLINONES AND THEIR SALTS | |
| AT347952B (en) | METHOD FOR PRODUCING NEW 1,1,1-TRIARYLALKYLAMINES AND THEIR SALTS | |
| AT361487B (en) | METHOD FOR PRODUCING NEW PYRAZOLO (1, 5C) CHINAZOLINES AND THEIR SALTS | |
| ATA262677A (en) | METHOD FOR PRODUCING NEW 7-AMINO-ALKYL-THIOPHYLLINES AND THEIR SALTS | |
| ATA134777A (en) | METHOD FOR PRODUCING NEW SUBSTITUTED 2-AMINOPURINES AND THEIR SALTS | |
| ATA353377A (en) | METHOD FOR PRODUCING NEW (1,2-DIHYDRO-2-OXO-NICOTINAMIDO) -ALKYL-BENZOLE-SULFONYL UREAS AND THEIR SALTS | |
| AT357550B (en) | PROCESS FOR PRODUCING NEW 2,9-DIOXATRICYCLO (4,3,1,03,7) DECANES AND THEIR SALTS | |
| AT350584B (en) | METHOD FOR PRODUCING NEW BENZYLIDE AMINOGUANIDINS AND THEIR SALTS | |
| AT359070B (en) | METHOD FOR PRODUCING NEW 2,4-DIAMINO -5-BENZYLPYRIMIDINES AND THEIR SALTS | |
| AT352139B (en) | METHOD FOR PRODUCING NEW 2,9-DIOXATRICYCLO- (4,3,1,03,7) DECANES AND THEIR SALTS | |
| AT358588B (en) | METHOD FOR PRODUCING NEW 1,2,3,4- TETRAHYDROISOCHINOLINES AND THEIR SALTS | |
| AT361002B (en) | METHOD FOR PRODUCING NEW 2,9-DIOXATRICYCLO (4,3,1,03,7) DECANES AND THEIR SALTS | |
| AT356293B (en) | METHOD FOR PRODUCING NEW D-6-ALKYL-8-CYANMETHYLERGOLINES-I AND THE SALTS THEREOF | |
| ATA677379A (en) | METHOD FOR PRODUCING NEW 1,3-THIAUOL COMPOUNDS AND THEIR SALTS | |
| AT357556B (en) | METHOD FOR PRODUCING NEW 3-AMINOMETHYL-4BETA-HYDROXY-2,9-DIOXATRICYCLO (4,3,1, 03,7) DECANES AND THEIR SALTS | |
| ATA42180A (en) | METHOD FOR PRODUCING NEW 2,4- -DIAMINO-5-BENZYLPYRIMIDINES AND THEIR SALTS | |
| ATA42280A (en) | METHOD FOR PRODUCING NEW 2,4- -DIAMINO-5-BENZYLPYRIMIDINES AND THEIR SALTS | |
| ATA745579A (en) | METHOD FOR PRODUCING NEW SUBSTITUTED HYDANTOINES AND THEIR SALTS |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |