PT67067B - Process for preparing a new organic compounds and more particulary 6-phenyl-1,2,4-triazolo/4,3-b/pyridazines - Google Patents
Process for preparing a new organic compounds and more particulary 6-phenyl-1,2,4-triazolo/4,3-b/pyridazinesInfo
- Publication number
- PT67067B PT67067B PT67067A PT6706777A PT67067B PT 67067 B PT67067 B PT 67067B PT 67067 A PT67067 A PT 67067A PT 6706777 A PT6706777 A PT 6706777A PT 67067 B PT67067 B PT 67067B
- Authority
- PT
- Portugal
- Prior art keywords
- pyridazines
- particulary
- triazolo
- phenyl
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/12—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/725,597 US4230705A (en) | 1976-09-22 | 1976-09-22 | 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazines and their uses in treating anxiety |
| US73039576A | 1976-10-07 | 1976-10-07 | |
| US73547576A | 1976-10-26 | 1976-10-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT67067A PT67067A (en) | 1977-10-01 |
| PT67067B true PT67067B (en) | 1979-02-19 |
Family
ID=27419081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT67067A PT67067B (en) | 1976-09-22 | 1977-09-22 | Process for preparing a new organic compounds and more particulary 6-phenyl-1,2,4-triazolo/4,3-b/pyridazines |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS5340798A (en) |
| AR (2) | AR218036A1 (en) |
| AT (1) | AT360034B (en) |
| AU (1) | AU513760B2 (en) |
| BG (1) | BG29287A3 (en) |
| CA (1) | CA1080712A (en) |
| DD (1) | DD132586A5 (en) |
| DE (1) | DE2741763A1 (en) |
| DK (1) | DK417377A (en) |
| ES (3) | ES462543A1 (en) |
| FI (1) | FI772802A (en) |
| FR (1) | FR2442848A1 (en) |
| GB (1) | GB1589237A (en) |
| GR (1) | GR71699B (en) |
| LU (1) | LU78150A1 (en) |
| NL (1) | NL7710389A (en) |
| NO (1) | NO773245L (en) |
| PT (1) | PT67067B (en) |
| RO (1) | RO72226A (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR70309B (en) * | 1979-10-29 | 1982-09-08 | Dow Chemical Co | |
| FR2473522A1 (en) * | 1980-01-16 | 1981-07-17 | Synthelabo | NOVEL DIHYDRO-2,3 IMIDAZO (1,2-B) PYRIDAZINE SUBSTITUTED DERIVATIVES AND MEDICAMENTS, PARTICULARLY USEFUL AS ANTIDEPRESSANTS, CONTAINING THEM |
| DE3173083D1 (en) * | 1980-03-22 | 1986-01-16 | Fbc Ltd | Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use |
| DE3217325A1 (en) * | 1982-05-08 | 1983-11-10 | Hoechst Ag, 6230 Frankfurt | 3-AMINO-6-ARYL-1,2,4-TRIAZOLO (4,3-B) -PYRIDAZINE, THEIR PRODUCTION AND USE |
| US4487930A (en) * | 1982-09-07 | 1984-12-11 | The Dow Chemical Company | 6-[(Cyclic amino)alkylamino]-tetrahydrotriazolo[3,4-a]phthalazines |
| FR2562071B1 (en) * | 1984-03-30 | 1986-12-19 | Sanofi Sa | TRIAZOLO (4,3-B) PYRIDAZINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| US4767765A (en) * | 1985-10-31 | 1988-08-30 | American Cyanamid Company | N-substituted-N-[3-(1,2,4-triazolo-[4,3-b]pyridazin-6-yl)phenyl]alkanamides, carbamates and ureas |
| US4654343A (en) * | 1985-10-31 | 1987-03-31 | American Cyanamid Company | N-substituted-N[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]alkanamides, carbamates and ureas |
| CN1251589A (en) * | 1996-07-25 | 2000-04-26 | 默克·夏普-道姆公司 | Substituted triazolo-pyridazine derivatives as ligands for GABA receptors |
| WO1999036423A1 (en) * | 1998-01-14 | 1999-07-22 | Merck Sharp & Dohme Limited | Triazolo-pyridazine derivatives as ligands for gaba receptors |
| GB9801210D0 (en) | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801234D0 (en) * | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GEP20032868B (en) | 1998-01-21 | 2003-01-27 | Merck Sharp & Dohme | Triazolo-Pyridazine Derivatives as Ligands for Gaba Receptors, Methods for Their Production, Pharmaceutical Compositions Containing the Same for Treatment and/or Prevention of disorders of Central Nervous System |
| GB9801202D0 (en) * | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801208D0 (en) * | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801397D0 (en) * | 1998-01-22 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801538D0 (en) | 1998-01-23 | 1998-03-25 | Merck Sharp & Dohme | Pharmaceutical product |
| US7645756B2 (en) * | 2004-02-18 | 2010-01-12 | Banyu Pharmaceutical Co. Ltd. | Nitrogenous fused heteroaromatic ring derivative |
| EP3548033B1 (en) * | 2016-11-28 | 2024-04-10 | Praxis Precision Medicines, Inc. | Compounds and their methods of use |
| MX2020012838A (en) | 2018-05-30 | 2021-07-16 | Praxis Prec Medicines Inc | Ion channel modulators. |
| US11773099B2 (en) | 2019-05-28 | 2023-10-03 | Praxis Precision Medicines, Inc. | Compounds and their methods of use |
| US11505554B2 (en) | 2019-05-31 | 2022-11-22 | Praxis Precision Medicines, Inc. | Substituted pyridines as ion channel modulators |
-
1977
- 1977-08-16 CA CA284,806A patent/CA1080712A/en not_active Expired
- 1977-08-19 GR GR54197A patent/GR71699B/el unknown
- 1977-09-07 AR AR269126A patent/AR218036A1/en active
- 1977-09-16 DE DE19772741763 patent/DE2741763A1/en not_active Withdrawn
- 1977-09-20 LU LU78150A patent/LU78150A1/xx unknown
- 1977-09-20 RO RO7791618A patent/RO72226A/en unknown
- 1977-09-20 BG BG7737371A patent/BG29287A3/en unknown
- 1977-09-21 NO NO773245A patent/NO773245L/en unknown
- 1977-09-21 AU AU28995/77A patent/AU513760B2/en not_active Expired
- 1977-09-21 AT AT677577A patent/AT360034B/en not_active IP Right Cessation
- 1977-09-21 DK DK417377A patent/DK417377A/en unknown
- 1977-09-22 FR FR7728639A patent/FR2442848A1/en active Pending
- 1977-09-22 DD DD7700201157A patent/DD132586A5/en unknown
- 1977-09-22 NL NL7710389A patent/NL7710389A/en not_active Application Discontinuation
- 1977-09-22 ES ES462543A patent/ES462543A1/en not_active Expired
- 1977-09-22 PT PT67067A patent/PT67067B/en unknown
- 1977-09-22 JP JP11344877A patent/JPS5340798A/en active Pending
- 1977-09-22 GB GB39619/77A patent/GB1589237A/en not_active Expired
- 1977-09-22 FI FI772802A patent/FI772802A/en not_active Application Discontinuation
-
1978
- 1978-12-18 AR AR274489A patent/AR217886A1/en active
-
1979
- 1979-02-16 ES ES477799A patent/ES477799A1/en not_active Expired
- 1979-02-16 ES ES477800A patent/ES477800A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT360034B (en) | 1980-12-10 |
| ES462543A1 (en) | 1979-06-16 |
| JPS5340798A (en) | 1978-04-13 |
| LU78150A1 (en) | 1978-01-23 |
| AU2899577A (en) | 1979-03-29 |
| NO773245L (en) | 1978-03-28 |
| RO72226A (en) | 1982-09-09 |
| BG29287A3 (en) | 1980-10-15 |
| ES477799A1 (en) | 1980-04-01 |
| FI772802A (en) | 1978-03-23 |
| DD132586A5 (en) | 1978-10-11 |
| DK417377A (en) | 1978-03-23 |
| GB1589237A (en) | 1981-05-07 |
| CA1080712A (en) | 1980-07-01 |
| AU513760B2 (en) | 1980-12-18 |
| GR71699B (en) | 1983-06-21 |
| DE2741763A1 (en) | 1978-03-23 |
| ES477800A1 (en) | 1979-10-16 |
| PT67067A (en) | 1977-10-01 |
| AR218036A1 (en) | 1980-05-15 |
| ATA677577A (en) | 1980-05-15 |
| NL7710389A (en) | 1978-03-28 |
| AR217886A1 (en) | 1980-04-30 |
| FR2442848A1 (en) | 1980-06-27 |
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