ATA206296A - Verfahren zur herstellung von clavulansäure-aminsalzen - Google Patents
Verfahren zur herstellung von clavulansäure-aminsalzenInfo
- Publication number
- ATA206296A ATA206296A AT0206296A AT206296A ATA206296A AT A206296 A ATA206296 A AT A206296A AT 0206296 A AT0206296 A AT 0206296A AT 206296 A AT206296 A AT 206296A AT A206296 A ATA206296 A AT A206296A
- Authority
- AT
- Austria
- Prior art keywords
- clavulic
- producing
- amine salts
- acid amine
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D503/02—Preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0206296A AT404728B (de) | 1996-11-27 | 1996-11-27 | Verfahren zur herstellung von clavulansäure-aminsalzen |
AU55562/98A AU5556298A (en) | 1996-11-27 | 1997-11-25 | Purification of fermented clavulanic acid |
PCT/EP1997/006578 WO1998023622A1 (en) | 1996-11-27 | 1997-11-25 | Purification of fermented clavulanic acid |
EP97951975A EP0941229B1 (de) | 1996-11-27 | 1997-11-25 | Reinigung von fermentierter clavulansäure |
AT97951975T ATE248842T1 (de) | 1996-11-27 | 1997-11-25 | Reinigung von fermentierter clavulansäure |
JP52427298A JP2001504508A (ja) | 1996-11-27 | 1997-11-25 | 発酵により生成したクラブラン酸の精製 |
DE69724641T DE69724641T2 (de) | 1996-11-27 | 1997-11-25 | Reinigung von fermentierter clavulansäure |
KR1019997004472A KR20000069057A (ko) | 1996-11-27 | 1997-11-25 | 발효 클라부란산의 정제 |
CA002273021A CA2273021A1 (en) | 1996-11-27 | 1997-11-25 | Purification of fermented clavulanic acid |
ARP970105539A AR013876A1 (es) | 1996-11-27 | 1997-11-26 | Un procedimiento para la produccion de acido clavulanico y sales farmaceuticamente aceptables del mismo |
US09/871,357 US20010029038A1 (en) | 1996-11-27 | 2001-05-31 | Purification of fermented clavulanic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0206296A AT404728B (de) | 1996-11-27 | 1996-11-27 | Verfahren zur herstellung von clavulansäure-aminsalzen |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA206296A true ATA206296A (de) | 1998-06-15 |
AT404728B AT404728B (de) | 1999-02-25 |
Family
ID=3526971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0206296A AT404728B (de) | 1996-11-27 | 1996-11-27 | Verfahren zur herstellung von clavulansäure-aminsalzen |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0941229B1 (de) |
JP (1) | JP2001504508A (de) |
KR (1) | KR20000069057A (de) |
AR (1) | AR013876A1 (de) |
AT (1) | AT404728B (de) |
AU (1) | AU5556298A (de) |
CA (1) | CA2273021A1 (de) |
DE (1) | DE69724641T2 (de) |
WO (1) | WO1998023622A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2408853C (en) * | 2000-05-13 | 2012-01-10 | Smithkline Beecham P.L.C. | Process |
GB0022841D0 (en) | 2000-09-18 | 2000-11-01 | Smithkline Beecham Plc | Process |
PL360254A1 (en) * | 2000-10-20 | 2004-09-06 | Biochemie Gesellschaft M.B.H. | Pharmaceutical compositions |
WO2014128538A1 (en) * | 2013-02-22 | 2014-08-28 | Vardhman Chemtech Limited | A process for the preparation of amoxicillin trihydrate |
CN105384758B (zh) * | 2015-12-01 | 2018-05-01 | 国药集团威奇达药业有限公司 | 克拉维酸胺盐的制备方法 |
CN109535183A (zh) * | 2017-09-21 | 2019-03-29 | 联邦制药(内蒙古)有限公司 | 一种制备克拉维酸叔辛胺的制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1508977A (en) * | 1974-04-20 | 1978-04-26 | Beecham Group Ltd | Beta-lactam antibiotic from streptomyces clavuligerus |
EP0026044B1 (de) * | 1979-08-24 | 1983-06-08 | Beecham Group Plc | Aminsalz der Clavulansäure, seine Herstellung und Verwendung |
ES2010144A6 (es) * | 1989-03-01 | 1989-10-16 | Pharma Mar S A Pharmar | Un procedimiento de floculacion-coagulacion de caldos de fermentacion de streptomyces sp. que permite la obtencion directa de liquidos completamente transparentes. |
ES2010143A6 (es) * | 1989-03-01 | 1989-10-16 | Pharma Mar S A Pharmar | Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp. |
SI9300296B (sl) * | 1992-06-11 | 1998-06-30 | Smithkline Beecham P.L.C. | Postopek in intermedianti za pripravo klavulanske kisline |
KR100200239B1 (ko) * | 1992-10-21 | 1999-06-15 | 김충환 | 클라불란산 칼륨염의 제조방법 |
GB9305565D0 (en) * | 1993-03-18 | 1993-05-05 | Smithkline Beecham Plc | Novel compounds and processes |
SI9400107A (en) * | 1994-03-02 | 1995-10-31 | Lek Tovarna Farmacevtskih | New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804. |
GB9426261D0 (en) * | 1994-12-24 | 1995-02-22 | Spurcourt Ltd | Clavulanic acid salts |
SI9500074A (en) * | 1995-03-10 | 1996-10-31 | Lek Tovarna Farmacevtskih | Process for preparation of alkani salts of clavulanic acid. |
SI9500134B (sl) * | 1995-04-20 | 2004-04-30 | Lek, | Postopek za pripravo čistih alkalijskih soli klavulanske kisline |
KR100200242B1 (ko) * | 1995-05-16 | 1999-06-15 | 김충환 | 클라불란산염의 제조 방법 |
-
1996
- 1996-11-27 AT AT0206296A patent/AT404728B/de not_active IP Right Cessation
-
1997
- 1997-11-25 EP EP97951975A patent/EP0941229B1/de not_active Expired - Lifetime
- 1997-11-25 WO PCT/EP1997/006578 patent/WO1998023622A1/en active IP Right Grant
- 1997-11-25 CA CA002273021A patent/CA2273021A1/en not_active Abandoned
- 1997-11-25 AU AU55562/98A patent/AU5556298A/en not_active Abandoned
- 1997-11-25 JP JP52427298A patent/JP2001504508A/ja active Pending
- 1997-11-25 KR KR1019997004472A patent/KR20000069057A/ko not_active Application Discontinuation
- 1997-11-25 DE DE69724641T patent/DE69724641T2/de not_active Expired - Lifetime
- 1997-11-26 AR ARP970105539A patent/AR013876A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2273021A1 (en) | 1998-06-04 |
DE69724641D1 (de) | 2003-10-09 |
AU5556298A (en) | 1998-06-22 |
EP0941229B1 (de) | 2003-09-03 |
AR013876A1 (es) | 2001-01-31 |
KR20000069057A (ko) | 2000-11-25 |
JP2001504508A (ja) | 2001-04-03 |
AT404728B (de) | 1999-02-25 |
DE69724641T2 (de) | 2004-08-05 |
WO1998023622A1 (en) | 1998-06-04 |
EP0941229A1 (de) | 1999-09-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELJ | Ceased due to non-payment of the annual fee |