AT89936B - Process for preparing a diethylbarbituric acid compound. - Google Patents
Process for preparing a diethylbarbituric acid compound.Info
- Publication number
- AT89936B AT89936B AT89936DA AT89936B AT 89936 B AT89936 B AT 89936B AT 89936D A AT89936D A AT 89936DA AT 89936 B AT89936 B AT 89936B
- Authority
- AT
- Austria
- Prior art keywords
- preparing
- acid compound
- diethylbarbituric acid
- compound
- salts
- Prior art date
Links
- 229960002319 barbital Drugs 0.000 title claims description 3
- -1 diethylbarbituric acid compound Chemical class 0.000 title claims description 3
- 238000004519 manufacturing process Methods 0.000 title claims 2
- 150000003839 salts Chemical class 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 150000007513 acids Chemical class 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- RMMXTBMQSGEXHJ-UHFFFAOYSA-N Aminophenazone Chemical compound O=C1C(N(C)C)=C(C)N(C)N1C1=CC=CC=C1 RMMXTBMQSGEXHJ-UHFFFAOYSA-N 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 150000007530 organic bases Chemical class 0.000 description 1
- 125000001997 phenyl group Chemical class [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
<Desc/Clms Page number 1>
VerfahrenzurDarstellungeinerDiäthylbarbitursäureverbindung.
EMI1.1
Andwendung eines Analgetieums. besonders zur Bekämpfung von Kopfschmerzen usw.. darauf ankommen muss. dass die Schmerzstillung ohne sehlafmachende Wirkung ermöglicht wird. um so in keiner Weise die Arbeitstätigkeit zu beeinträchtigen.
Bei der neuen Verbindung handelt es sieh um kein Salz. etwa nach \rt der bekannten Salze der Dialkylbarbitursäuren bzw. Aralkylbajbitursäuren mit organischen Basen bzw. der Salze des Phenyl-
EMI1.2
amiden. Diese Salze unterscheiden sieh in der Farbe in keiner Weise von der Farbe der Muttersubstanzen, während nach der vorliegenden Erfindung aus weissen Ausgangsstoffen eine Verbindung erhalten wird, die gelb ist. Schon dieser Umstand beweist. dass durch das vorliegende Verfahren eine molekulare Änderung herbeigeführt wird. Die neue Verbindung verhält sich daher chemisch auch ganz anders als die erwähnten Salze. Während bei diesen die Reaktion der einzelnen Ausgangstoffe unverändert erhalten ist, ist das bei der vorliegenden Verbindung nicht der Fall.
So gibt das dimethylaminophenyldimethyl- pyrazolon mit Wasserstoffsuperoxyd und Essigsäure bei gelindem wärmen eine charakteristische Blaufärbung. die bei der neuen Verbindung nicht eintritt. E folgt jedoch ihre. Aufspaltung durch MineralSäuren in der Wärme, so erscheint die Reaktion wieder.
Das vorliegende Verfahren führt also überraschenderweise zu einer besonders gearteten. neuen Verbindung mit neuen wertvollen Eigenschaften.
**WARNUNG** Ende DESC Feld kannt Anfang CLMS uberlappen**.
<Desc / Clms Page number 1>
Process for the preparation of a diethylbarbituric acid compound.
EMI1.1
Application of an analgesic. especially to fight headaches etc .. it has to matter. that the pain relief is made possible without sleep-inducing effect. so as not to impair work activity in any way.
The new compound is not a salt. about the known salts of dialkylbarbituric acids or aralkylbajbituric acids with organic bases or the salts of phenyl
EMI1.2
amides. These salts do not differ in color from the color of the parent substances, while according to the present invention a compound is obtained from white starting materials which is yellow. This fact alone proves it. that a molecular change is brought about by the present process. The new compound therefore behaves chemically very differently than the salts mentioned. While the reaction of the individual starting materials remains unchanged in these, this is not the case with the present compound.
Dimethylaminophenyldimethylpyrazolone with hydrogen peroxide and acetic acid gives a characteristic blue coloration when heated gently. which does not occur with the new connection. However, E follows theirs. Splitting by mineral acids in the heat, the reaction reappears.
The present method surprisingly leads to a particularly special one. new connection with new valuable properties.
** WARNING ** End of DESC field may overlap beginning of CLMS **.
Claims (1)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE89936X | 1920-01-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT89936B true AT89936B (en) | 1922-11-10 |
Family
ID=5642994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89936D AT89936B (en) | 1920-01-26 | 1921-01-05 | Process for preparing a diethylbarbituric acid compound. |
Country Status (2)
| Country | Link |
|---|---|
| AT (1) | AT89936B (en) |
| CH (1) | CH91247A (en) |
-
1921
- 1921-01-05 AT AT89936D patent/AT89936B/en active
- 1921-01-08 CH CH91247D patent/CH91247A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH91247A (en) | 1921-10-17 |
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