AT73479B - Process for the production of an easily absorbable, durable, non-hygroscopic calcium preparation. - Google Patents
Process for the production of an easily absorbable, durable, non-hygroscopic calcium preparation.Info
- Publication number
- AT73479B AT73479B AT73479DA AT73479B AT 73479 B AT73479 B AT 73479B AT 73479D A AT73479D A AT 73479DA AT 73479 B AT73479 B AT 73479B
- Authority
- AT
- Austria
- Prior art keywords
- production
- durable
- calcium preparation
- easily absorbable
- hygroscopic
- Prior art date
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Description
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Verfahren zur Herstellung eines leicht resorbierbaren, haltbaren, nichthygroskopischen
Kalkpräparates.
Wie Emmerieh und Loew beobachteten, wird Calcium aus seinen Sätzen vom Organismus besser resorbiert, wenn das Blut eine gewisse erhöhte Alkalescenz besitzt.
Dieses könnte am besten durch Zuführung des Natriumsalzes der dem menschlichen
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Natrium, das im Handel nur in Form einer hochkonzentrierten, wässerigen Lösung vorrätig gehalten wird, wegen seiner Hygroskopizität nicht verwendbar.
Es wurde nun beobachtet, dass die hochkonzentrierte Lösung des Handels beim Zusammenmischen mit nicht zu geringen Mengen des für die Kalktherapio als besonders brauchbar erfundenen Calciumlactats unter Erwärmung ein krümliges Produkt gibt, das sich an der Luft auf einen bestimmten Wassergehalt einstellt und ihn dann festhält.
Geht man im Zusatz des Calciumlactats unter das Verhältnis von 1/2 Molekül Calciumsalz für 1 Molekül Natriumsalz herab, so resultieren wieder hygroskopischProdukte. Bei Verwendung von 1 Molekül Calciumlactat auf 2 Moleküle Natriumlaetat
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einstellt.
Ein ähnliches, allerdings nur 2 Moleküle Kristallwasser enthaltendes Doppelsalz ist vor mehr als 50 Jahren bereits einmal in der Literatur beschrieben worden. Es wurde aus der wässerigen Lösung der Komponenten durch Auskristallisierenlassen erhalten.
Über die physikalischen Eigenschaften des Produktes, insbesondere seine Haltbarkeit an der Luft finden sich dort aber keine Angaben, auch nicht über die Ausbeute, die aber, weil sich das Doppelsalz in Wasser leicht löst, technisch natürlich völlig unzulänglich ist
Beispiel1.
238 g eines 9% Wasser enthaltenden milchsauren Kalkes werden mit 280 g eines milchsauren Natriums mit SO/o Wasser zusammengemischt, wobei das mehlige Calciumlaetai
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308 Teile eines 5 Moleküle Kristallwasser enthaltenden milchsauren lialkes werden m't 280 ölen eines milchsauren Natriums mit 20% Wassergehalt innig gemischt, das unter Temperaturänderung erstarrende Produkt wird durch ein Sieb gedrückt und bei zirka 60
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zurTablettenherstellungverwendetwerden.
**WARNUNG** Ende DESC Feld kannt Anfang CLMS uberlappen**.
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Process for the production of an easily absorbable, durable, non-hygroscopic
Lime preparation.
As Emmerieh and Loew observed, calcium from its deposits is better absorbed by the organism when the blood has a certain increased alkalinity.
This could best be done by adding the sodium salt to the human
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Sodium, which is only available commercially in the form of a highly concentrated aqueous solution, cannot be used due to its hygroscopicity.
It has now been observed that the highly concentrated commercial solution when mixed with not too small amounts of the calcium lactate invented to be particularly useful for calcium therapy gives a crumbly product when heated, which adjusts to a certain water content in the air and then holds it.
If the addition of calcium lactate goes below the ratio of 1/2 molecule of calcium salt to 1 molecule of sodium salt, the result is again hygroscopic products. When using 1 molecule of calcium lactate to 2 molecules of sodium acetate
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adjusts.
A similar double salt containing only 2 molecules of water of crystallization was already described in the literature more than 50 years ago. It was obtained from the aqueous solution of the components by allowing it to crystallize out.
There is no information there about the physical properties of the product, especially its durability in air, nor about the yield, which is of course completely inadequate technically because the double salt dissolves easily in water
Example 1.
238 g of a lactic acid lime containing 9% water are mixed together with 280 g of a lactic acid sodium with SO / o water, the floury calcium lay
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308 parts of a lactic acid liqueur containing 5 molecules of water of crystallization are intimately mixed with oils of lactic acid sodium with 20% water content
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be used for tablet production.
** WARNING ** End of DESC field may overlap beginning of CLMS **.
Claims (1)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT73479T | 1915-12-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
AT73479B true AT73479B (en) | 1917-06-25 |
Family
ID=3595150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT73479D AT73479B (en) | 1915-12-01 | 1915-12-01 | Process for the production of an easily absorbable, durable, non-hygroscopic calcium preparation. |
Country Status (1)
Country | Link |
---|---|
AT (1) | AT73479B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2856326A (en) * | 1956-03-19 | 1958-10-14 | Nat Dairy Prod Corp | Lactate composition for treatment of bovine ketosis |
-
1915
- 1915-12-01 AT AT73479D patent/AT73479B/en active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2856326A (en) * | 1956-03-19 | 1958-10-14 | Nat Dairy Prod Corp | Lactate composition for treatment of bovine ketosis |
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