AT73479B - Process for the production of an easily absorbable, durable, non-hygroscopic calcium preparation. - Google Patents

Process for the production of an easily absorbable, durable, non-hygroscopic calcium preparation.

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Publication number
AT73479B
AT73479B AT73479DA AT73479B AT 73479 B AT73479 B AT 73479B AT 73479D A AT73479D A AT 73479DA AT 73479 B AT73479 B AT 73479B
Authority
AT
Austria
Prior art keywords
production
durable
calcium preparation
easily absorbable
hygroscopic
Prior art date
Application number
Other languages
German (de)
Original Assignee
Johann A Wuelfing Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johann A Wuelfing Chem Fab filed Critical Johann A Wuelfing Chem Fab
Application granted granted Critical
Publication of AT73479B publication Critical patent/AT73479B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Description

  

   <Desc/Clms Page number 1> 
 



  Verfahren zur Herstellung eines leicht resorbierbaren, haltbaren, nichthygroskopischen
Kalkpräparates. 



   Wie   Emmerieh   und Loew beobachteten, wird Calcium aus seinen   Sätzen vom   Organismus besser resorbiert, wenn das Blut eine gewisse erhöhte Alkalescenz besitzt. 



   Dieses könnte am besten durch Zuführung des Natriumsalzes der dem menschlichen 
 EMI1.1 
 Natrium, das im Handel nur in Form einer hochkonzentrierten, wässerigen Lösung vorrätig gehalten wird, wegen seiner Hygroskopizität nicht verwendbar. 



   Es wurde nun beobachtet, dass die hochkonzentrierte Lösung des Handels beim Zusammenmischen mit nicht zu geringen Mengen des für die Kalktherapio als besonders brauchbar erfundenen Calciumlactats unter Erwärmung ein   krümliges   Produkt gibt, das sich an der Luft auf einen bestimmten Wassergehalt einstellt und ihn dann festhält. 



   Geht man im Zusatz des Calciumlactats unter das Verhältnis von 1/2 Molekül Calciumsalz für 1 Molekül Natriumsalz herab, so resultieren wieder hygroskopischProdukte. Bei Verwendung von 1 Molekül Calciumlactat auf   2 Moleküle Natriumlaetat   
 EMI1.2 
 einstellt. 



   Ein ähnliches, allerdings nur 2 Moleküle Kristallwasser enthaltendes Doppelsalz ist vor mehr als 50 Jahren bereits einmal in der Literatur beschrieben worden. Es wurde aus der   wässerigen   Lösung der Komponenten durch Auskristallisierenlassen   erhalten.   



   Über die physikalischen Eigenschaften des Produktes, insbesondere seine Haltbarkeit an der Luft finden sich dort aber keine Angaben, auch nicht   über   die Ausbeute, die aber, weil sich das Doppelsalz in Wasser leicht löst, technisch natürlich völlig unzulänglich ist 
Beispiel1. 



   238 g eines 9% Wasser enthaltenden   milchsauren   Kalkes werden mit 280   g eines   milchsauren Natriums mit   SO/o   Wasser zusammengemischt, wobei das   mehlige     Calciumlaetai   
 EMI1.3 
 



   308 Teile eines 5 Moleküle Kristallwasser enthaltenden milchsauren   lialkes werden m't     280 ölen   eines milchsauren Natriums mit 20% Wassergehalt innig gemischt, das unter   Temperaturänderung   erstarrende Produkt wird durch ein Sieb gedrückt und bei zirka 60  
 EMI1.4 
 zurTablettenherstellungverwendetwerden. 

**WARNUNG** Ende DESC Feld kannt Anfang CLMS uberlappen**.



   <Desc / Clms Page number 1>
 



  Process for the production of an easily absorbable, durable, non-hygroscopic
Lime preparation.



   As Emmerieh and Loew observed, calcium from its deposits is better absorbed by the organism when the blood has a certain increased alkalinity.



   This could best be done by adding the sodium salt to the human
 EMI1.1
 Sodium, which is only available commercially in the form of a highly concentrated aqueous solution, cannot be used due to its hygroscopicity.



   It has now been observed that the highly concentrated commercial solution when mixed with not too small amounts of the calcium lactate invented to be particularly useful for calcium therapy gives a crumbly product when heated, which adjusts to a certain water content in the air and then holds it.



   If the addition of calcium lactate goes below the ratio of 1/2 molecule of calcium salt to 1 molecule of sodium salt, the result is again hygroscopic products. When using 1 molecule of calcium lactate to 2 molecules of sodium acetate
 EMI1.2
 adjusts.



   A similar double salt containing only 2 molecules of water of crystallization was already described in the literature more than 50 years ago. It was obtained from the aqueous solution of the components by allowing it to crystallize out.



   There is no information there about the physical properties of the product, especially its durability in air, nor about the yield, which is of course completely inadequate technically because the double salt dissolves easily in water
Example 1.



   238 g of a lactic acid lime containing 9% water are mixed together with 280 g of a lactic acid sodium with SO / o water, the floury calcium lay
 EMI1.3
 



   308 parts of a lactic acid liqueur containing 5 molecules of water of crystallization are intimately mixed with oils of lactic acid sodium with 20% water content
 EMI1.4
 be used for tablet production.

** WARNING ** End of DESC field may overlap beginning of CLMS **.

 

Claims (1)

PATENT-ANSPRUCH : Verfahren zur Überführung des syrupösen, stark hygroskopischen Natriumlactats in ein pulverisierbares, nicht hygroskopisches Produkt, dadurch gekennzeichnet, dass man d : ts EMI1.5 **WARNUNG** Ende CLMS Feld Kannt Anfang DESC uberlappen**. PATENT CLAIM: Process for converting the syrupy, highly hygroscopic sodium lactate into a pulverizable, non-hygroscopic product, characterized in that d: ts EMI1.5 ** WARNING ** End of CLMS field may overlap beginning of DESC **.
AT73479D 1915-12-01 1915-12-01 Process for the production of an easily absorbable, durable, non-hygroscopic calcium preparation. AT73479B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT73479T 1915-12-01

Publications (1)

Publication Number Publication Date
AT73479B true AT73479B (en) 1917-06-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
AT73479D AT73479B (en) 1915-12-01 1915-12-01 Process for the production of an easily absorbable, durable, non-hygroscopic calcium preparation.

Country Status (1)

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AT (1) AT73479B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2856326A (en) * 1956-03-19 1958-10-14 Nat Dairy Prod Corp Lactate composition for treatment of bovine ketosis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2856326A (en) * 1956-03-19 1958-10-14 Nat Dairy Prod Corp Lactate composition for treatment of bovine ketosis

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