AT506505A1 - Cylindrical-shaped mechanical concentration device for diagnostic analysis of particles of body fluid, has silicone rubber seal sealing amount of fluid compressed by transparent base plate and transparent hollow cover in sterile manner - Google Patents

Cylindrical-shaped mechanical concentration device for diagnostic analysis of particles of body fluid, has silicone rubber seal sealing amount of fluid compressed by transparent base plate and transparent hollow cover in sterile manner Download PDF

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Publication number
AT506505A1
AT506505A1 AT2582008A AT2582008A AT506505A1 AT 506505 A1 AT506505 A1 AT 506505A1 AT 2582008 A AT2582008 A AT 2582008A AT 2582008 A AT2582008 A AT 2582008A AT 506505 A1 AT506505 A1 AT 506505A1
Authority
AT
Austria
Prior art keywords
cylindrical
particles
base plate
silicone rubber
hollow lid
Prior art date
Application number
AT2582008A
Other languages
German (de)
Inventor
Hans G Dr Loew
Original Assignee
Hans G Dr Loew
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hans G Dr Loew filed Critical Hans G Dr Loew
Priority to AT2582008A priority Critical patent/AT506505A1/en
Publication of AT506505A1 publication Critical patent/AT506505A1/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G01N2001/4088—Concentrating samples by other techniques involving separation of suspended solids filtration

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The device has a transparent base plate (P) for diagnostic analysis purposes. A particle filter plate (F) is attached to a piston pin (K) and oriented to an open end of a cylindrical hollow cover (H). A silicone rubber seal (D) seals amount of fluid compressed by the base plate and the cover in sterile manner. The cover is fitted on a cylindrical threaded cup (B) after filling fluid particle suspension into the cup with external thread, and is pressed into the cup by multiple rotary motion along thread processes. The motion is locked by the seal pressed on lower side of the cover.

Description

       

  Diagnostische Analysezwecke erfordern die Manipulation von nicht sterilen Körperflüssigkeiten. Eine in Kunststoff realisierbare aus zwei Teilen bestehende Vorrichtung vereinfacht mehrere Arbeitsschritte zur Trennung von Zellen bzw. Sedimenten aus der Flüssigphase. Eine zylindrischer Hohldeckel H mit Innengewinde samt Kolbendorn K trägt eine Filterplatte F ( s. Skizze 1 ). Nach Einfüllen der flüssigen Partikelsuspension in den Becher B mit Aussengewinde wird der Hohldeckel H auf Becher B aufgesetzt und durch mehrfache Drehbewegung entlang des Gewindeverlaufes in den Becher gepresst. Mit dem Hohldeckel gleitet auch der Kolbendorn K mit der Filterplatte in das Innere des Bechers. Vorhandene Partikel werden durch einen Filter hin zur transparenten Bodenplatte P gesammelt während die Flüssigkeit durch die Filterplatte gepresst wird und sich oberhalb der Platte sammelt.

   Die Drehbewegung wird durch eine auf der Unterseite des Hohldeckels eingepresste Silikongummidichtung D abgeschlossen. Damit ist der Behälter dicht und erlaubt die sterile Weiterverwendung für Zähl- und Analysezwecke. 

  
18/02 2008 MO 10 40 [SE/EM NR 9405] (c)001



  Diagnostic analysis requires the manipulation of non-sterile body fluids. An implementable in plastic two-piece device simplifies several steps for the separation of cells or sediments from the liquid phase. A cylindrical hollow cover H with internal thread including piston mandrel K carries a filter plate F (see sketch 1). After filling the liquid particle suspension in the cup B with external thread of the hollow cover H is placed on cup B and pressed by multiple rotational movement along the thread course in the cup. With the hollow lid and the Kolbendorn K slides with the filter plate in the interior of the cup. Existing particles are collected through a filter towards the transparent bottom plate P as the liquid is forced through the filter plate and collects above the plate.

   The rotational movement is completed by a pressed-in on the underside of the hollow lid silicone rubber seal D. Thus, the container is sealed and allows the sterile re-use for counting and analysis purposes.

  
18/02 2008 MO 10 40 [SE / EM NR 9405] (c) 001

Claims (1)

<EMI ID=2.1>  <EMI ID = 2.1> ANSPRÜCHE: CLAIMS: 1. Zylindrische Bauform einer mechanischen Konzentrationsvorrichtung für Partikeln aus Flüssigkeiten bestehend aus 2 nicht zusammenhängenden ineinanderschraubbaren Geräteteilen 1. Cylindrical design of a mechanical concentration device for particles of liquids consisting of 2 non-contiguous zusammeneinanderschraubbaren device parts 2. zylindrische Bauform einer mechanischen Konzentrationsvorrichtung von Partikeln mit transparenter Bodenplatte zu Analysezwecken 2. cylindrical shape of a mechanical concentration device of particles with transparent bottom plate for analysis purposes 3. Konzentrationsvorrichtung nach Anspruch 1 und 2, gekennzeichnet durch einen koaxial mit einem zylindrischen Hohldeckel innenseitig verbundenen Kolbendorn, an welchen eine zum offenen Ende des Hohldeckels orientierte Partikcl-Filterplatte angebaut ist. 3. Concentrating device according to claim 1 and 2, characterized by a coaxial with a cylindrical hollow lid on the inside connected piston mandrel, on which an open end of the hollow lid oriented Partikcl filter plate is grown. 4. Konzentrationsvorrichtung nach Anspruch 1 und 2, gekennzeichnet durch einen Hohldeckel, welcher ein innenseitiges Gewinde trägt und einen dazu passenden zylindrischen Gewindebecher, welcher ein aussenseitiges Gewinde trägt. 4. Concentrating device according to claim 1 and 2, characterized by a hollow lid, which carries an inside thread and a matching cylindrical threaded cup, which carries an external thread. 5. Konzentrationsvorrichtung nach Anspruch 4, gekennzeichnet durch Gewindegänge mit rechteckigem Profil, einem Durchmesser von maximal 5 cm , Zylinderlänge bis maximal 12 cm und einer Steigung zwischen 1 :5 und 1 :7 5. Concentrating device according to claim 4, characterized by threads with a rectangular profile, a maximum diameter of 5 cm, cylinder length to a maximum of 12 cm and a slope between 1: 5 and 1: 7 6. Konzentrationsvorrichtung nach Anspruch 1 und 2 , gekennzeichnet durch eine an der Innenseite des Hohldeckels eingeprcssie ringförmige Flachdichtung aus Silikonkautschuk zur sterilen Abdichtung der durch die beiden Geräteteile zusammengepressten Flüssigkeitsmenge. Bis zum Kontakt des Gewindebechers zur Silikondichtung während der Verschraubungsbewegung kann Restluft aus dem Volumen des Hohldeckels nach aussen entweichen. 6. Concentrating device according to claim 1 and 2, characterized by a eingprcssie on the inside of the hollow lid annular gasket made of silicone rubber for the sterile sealing of the compressed by the two parts of the device liquid quantity. Until the contact of the threaded cup to the silicone gasket during the screwing movement, residual air can escape out of the volume of the hollow lid to the outside. 18/02 2008 MO 10:40 [SE/EM NR 8405] 0003 18/02 2008 MO 10:40 [SE / EM NO 8405] 0003
AT2582008A 2008-02-18 2008-02-18 Cylindrical-shaped mechanical concentration device for diagnostic analysis of particles of body fluid, has silicone rubber seal sealing amount of fluid compressed by transparent base plate and transparent hollow cover in sterile manner AT506505A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT2582008A AT506505A1 (en) 2008-02-18 2008-02-18 Cylindrical-shaped mechanical concentration device for diagnostic analysis of particles of body fluid, has silicone rubber seal sealing amount of fluid compressed by transparent base plate and transparent hollow cover in sterile manner

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT2582008A AT506505A1 (en) 2008-02-18 2008-02-18 Cylindrical-shaped mechanical concentration device for diagnostic analysis of particles of body fluid, has silicone rubber seal sealing amount of fluid compressed by transparent base plate and transparent hollow cover in sterile manner

Publications (1)

Publication Number Publication Date
AT506505A1 true AT506505A1 (en) 2009-09-15

Family

ID=41057705

Family Applications (1)

Application Number Title Priority Date Filing Date
AT2582008A AT506505A1 (en) 2008-02-18 2008-02-18 Cylindrical-shaped mechanical concentration device for diagnostic analysis of particles of body fluid, has silicone rubber seal sealing amount of fluid compressed by transparent base plate and transparent hollow cover in sterile manner

Country Status (1)

Country Link
AT (1) AT506505A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109289958A (en) * 2017-07-24 2019-02-01 郑州威瑞生物技术有限公司 Clamshell pipe cap and clamshell test tube component
WO2020099475A3 (en) * 2018-11-13 2020-07-16 Sarstedt Ag & Co. Kg Device and method for obtaining a cell-free sample fraction

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109289958A (en) * 2017-07-24 2019-02-01 郑州威瑞生物技术有限公司 Clamshell pipe cap and clamshell test tube component
CN109289958B (en) * 2017-07-24 2023-10-31 郑州威瑞生物技术有限公司 Flip formula cap and flip formula test tube assembly
WO2020099475A3 (en) * 2018-11-13 2020-07-16 Sarstedt Ag & Co. Kg Device and method for obtaining a cell-free sample fraction

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Effective date: 20160515