AT384023B - Verfahren zur herstellung von neuen 2,4-diamino-5-(subst.)pyrimidinen und deren salzen, n-oxiden und n-acylderivaten - Google Patents

Verfahren zur herstellung von neuen 2,4-diamino-5-(subst.)pyrimidinen und deren salzen, n-oxiden und n-acylderivaten

Info

Publication number
AT384023B
AT384023B AT483781A AT483781A AT384023B AT 384023 B AT384023 B AT 384023B AT 483781 A AT483781 A AT 483781A AT 483781 A AT483781 A AT 483781A AT 384023 B AT384023 B AT 384023B
Authority
AT
Austria
Prior art keywords
subst
pyrimidines
diamino
oxides
salts
Prior art date
Application number
AT483781A
Other languages
English (en)
Other versions
ATA483781A (de
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Priority to AT483781A priority Critical patent/AT384023B/de
Publication of ATA483781A publication Critical patent/ATA483781A/de
Application granted granted Critical
Publication of AT384023B publication Critical patent/AT384023B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/40—Nitrogen atoms attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/64—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with oxygen atoms directly attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
AT483781A 1980-11-11 1981-11-10 Verfahren zur herstellung von neuen 2,4-diamino-5-(subst.)pyrimidinen und deren salzen, n-oxiden und n-acylderivaten AT384023B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT483781A AT384023B (de) 1980-11-11 1981-11-10 Verfahren zur herstellung von neuen 2,4-diamino-5-(subst.)pyrimidinen und deren salzen, n-oxiden und n-acylderivaten

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8036135 1980-11-11
AT483781A AT384023B (de) 1980-11-11 1981-11-10 Verfahren zur herstellung von neuen 2,4-diamino-5-(subst.)pyrimidinen und deren salzen, n-oxiden und n-acylderivaten

Publications (2)

Publication Number Publication Date
ATA483781A ATA483781A (de) 1987-02-15
AT384023B true AT384023B (de) 1987-09-25

Family

ID=25601570

Family Applications (1)

Application Number Title Priority Date Filing Date
AT483781A AT384023B (de) 1980-11-11 1981-11-10 Verfahren zur herstellung von neuen 2,4-diamino-5-(subst.)pyrimidinen und deren salzen, n-oxiden und n-acylderivaten

Country Status (1)

Country Link
AT (1) AT384023B (de)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB957797A (en) * 1959-09-03 1964-05-13 Wellcome Found Method for making 2,4-diamino-5-arylmethylpyrimidines and intermediates therefor
DE2252807A1 (de) * 1971-12-01 1973-06-07 Hoffmann La Roche Neue benzylpyrimidine
AT337185B (de) * 1972-06-26 1977-06-10 Hoffmann La Roche Verfahren zur herstellung neuer n-oxyde von 2,4-diamino-5-(3-methoxy-4,5-methylendioxybenzyl)-pyrimidin und ihrer saureadditionssalze

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB957797A (en) * 1959-09-03 1964-05-13 Wellcome Found Method for making 2,4-diamino-5-arylmethylpyrimidines and intermediates therefor
DE2252807A1 (de) * 1971-12-01 1973-06-07 Hoffmann La Roche Neue benzylpyrimidine
AT321310B (de) * 1971-12-01 1975-03-25 Hoffmann La Roche Verfahren zur Herstellung von neuen Benzylpyrimidinen und von deren Säureadditionssalzen
AT337185B (de) * 1972-06-26 1977-06-10 Hoffmann La Roche Verfahren zur herstellung neuer n-oxyde von 2,4-diamino-5-(3-methoxy-4,5-methylendioxybenzyl)-pyrimidin und ihrer saureadditionssalze

Also Published As

Publication number Publication date
ATA483781A (de) 1987-02-15

Similar Documents

Publication Publication Date Title
ATA122485A (de) Verfahren zur herstellung von neuen 1,4-dihydro-4-oxonaphthyridin-derivaten und deren salzen
AT363479B (de) Verfahren zur herstellung von neuen imidazo-chinazolinen, deren tautomeren und salzen
AT384805B (de) Verfahren zur herstellung von neuen 1,2-diaminocyclobuten-3,4-dionen und deren salzen
ATA63678A (de) Verfahren zur herstellung von neuen 1-(1,3dioxolan-2-ylmethyl)-1h-imidazolen und -1h-1,2,4- triaxolen und deren salzen
ATA220185A (de) Verfahren zur herstellung von neuen -aryl-5h-2,3-benzodiazepin-derivaten und deren saeureadditionssalzen
AT383120B (de) Verfahren zur herstellung von neuen 3,4-dihydro-5h-2,3-benzodiazepinderivaten sowie von deren saeureadditionssalzen
AT363491B (de) Verfahren zur herstellung von neuen 1,3,8trisubstituierten xanthinen und deren salzen
AT357553B (de) Verfahren zur herstellung von neuen 2-(2,2- diarylalkyl)-1-azabicyclo(2.2.2)octanen und von deren salzen
AT381705B (de) Verfahren zur herstellung von neuen thiazolidindion-derivaten und deren salzen
AT368156B (de) Verfahren zur herstellung von neuen 4-oxo-4hpyrido(1,2-a)pyrimidinderivaten sowie von deren saeureadditions- oder quaternaeren salzen
AT362381B (de) Verfahren zur herstellung von neuen 2,4-diamino -pyrimidinderivaten und von deren alkalimetall- salzen
DE3886936D1 (de) 2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLEN 2-PGI-DERIVATE, VERFAHREN ZUR HERSTELLUNG UND DEREN VERWENDUNG.
AT381494B (de) Verfahren zur herstellung neuer 2,3,4-trinor-1,5inter-m-phenylen-prostacyclin-derivaten und von deren salzen
AT379804B (de) Verfahren zur herstellung von neuen phenaethylimidazolderivaten und von deren salzen
AT357144B (de) Verfahren zur herstellung von neuen 1-acyl-2- hydroxy-1,3-diaminopropanen und deren salzen
AT384023B (de) Verfahren zur herstellung von neuen 2,4-diamino-5-(subst.)pyrimidinen und deren salzen, n-oxiden und n-acylderivaten
ATA238481A (de) Verfahren zur herstellung von neuen acylaminophenylpyridinderivaten und deren salzen
AT359070B (de) Verfahren zur herstellung von neuen 2,4-diamino -5-benzylpyrimidinen und deren salzen
DE3784218D1 (de) Neue thiochinacridone und isothiochinacridone, verfahren zu deren herstellung und verwendung.
AT384806B (de) Verfahren zur herstellung von neuen 4-aryl-2-methyl-1,2,3,4-tetrahydro-isochinolinderivaten und deren salzen
DE3582398D1 (de) Verfahren zur herstellung von substituierten pyridinen.
DE3667491D1 (de) Verfahren zur herstellung von 1-methyl-1,4-androstadien-3,17-dion.
AT381303B (de) Verfahren zur herstellung von neuen, optisch aktiven und racemischen 5-substituierten-4-oxo -pgi1-derivaten sowie von deren salzen
DE3783065D1 (de) 5-fluorouracil-derivate und verfahren zu deren herstellung.
ATA400482A (de) Verfahren zur herstellung von neuen n-substituierten ergolin- und 9,10-didehydroergolin-8-carboxamid-derivaten

Legal Events

Date Code Title Description
EIH Change in the person of patent owner
ELJ Ceased due to non-payment of the annual fee