AT358046B - Verfahren zur herstellung von neuen trans-5a- -aryl-decahydrobenzazepinen und ihren saeure- additionssalzen - Google Patents

Verfahren zur herstellung von neuen trans-5a- -aryl-decahydrobenzazepinen und ihren saeure- additionssalzen

Info

Publication number
AT358046B
AT358046B AT782277A AT782277A AT358046B AT 358046 B AT358046 B AT 358046B AT 782277 A AT782277 A AT 782277A AT 782277 A AT782277 A AT 782277A AT 358046 B AT358046 B AT 358046B
Authority
AT
Austria
Prior art keywords
decahydrobenzazepines
aryl
acid addition
addition salts
producing new
Prior art date
Application number
AT782277A
Other languages
German (de)
English (en)
Other versions
ATA782277A (de
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ATA782277A publication Critical patent/ATA782277A/de
Application granted granted Critical
Publication of AT358046B publication Critical patent/AT358046B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT782277A 1976-11-02 1977-11-02 Verfahren zur herstellung von neuen trans-5a- -aryl-decahydrobenzazepinen und ihren saeure- additionssalzen AT358046B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/737,959 US4141894A (en) 1976-11-02 1976-11-02 Trans-5a-aryl-decahydrobenzazepines

Publications (2)

Publication Number Publication Date
ATA782277A ATA782277A (de) 1980-01-15
AT358046B true AT358046B (de) 1980-08-11

Family

ID=24965985

Family Applications (1)

Application Number Title Priority Date Filing Date
AT782277A AT358046B (de) 1976-11-02 1977-11-02 Verfahren zur herstellung von neuen trans-5a- -aryl-decahydrobenzazepinen und ihren saeure- additionssalzen

Country Status (26)

Country Link
US (1) US4141894A (US06534493-20030318-C00166.png)
JP (1) JPS5356683A (US06534493-20030318-C00166.png)
AR (1) AR221835A1 (US06534493-20030318-C00166.png)
AT (1) AT358046B (US06534493-20030318-C00166.png)
AU (1) AU510911B2 (US06534493-20030318-C00166.png)
BE (1) BE860315A (US06534493-20030318-C00166.png)
BG (1) BG28417A3 (US06534493-20030318-C00166.png)
CA (2) CA1096861A (US06534493-20030318-C00166.png)
DD (1) DD133797A5 (US06534493-20030318-C00166.png)
DE (1) DE2748468A1 (US06534493-20030318-C00166.png)
DK (1) DK485177A (US06534493-20030318-C00166.png)
ES (1) ES463782A1 (US06534493-20030318-C00166.png)
FR (1) FR2369268A1 (US06534493-20030318-C00166.png)
GB (1) GB1585296A (US06534493-20030318-C00166.png)
GR (1) GR70052B (US06534493-20030318-C00166.png)
IE (1) IE45899B1 (US06534493-20030318-C00166.png)
IL (1) IL53235A0 (US06534493-20030318-C00166.png)
NL (1) NL7712052A (US06534493-20030318-C00166.png)
PH (1) PH13506A (US06534493-20030318-C00166.png)
PL (1) PL108916B1 (US06534493-20030318-C00166.png)
PT (1) PT67195B (US06534493-20030318-C00166.png)
RO (1) RO72899B (US06534493-20030318-C00166.png)
SE (1) SE7712219L (US06534493-20030318-C00166.png)
SU (1) SU843743A3 (US06534493-20030318-C00166.png)
YU (1) YU257577A (US06534493-20030318-C00166.png)
ZA (1) ZA776498B (US06534493-20030318-C00166.png)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1298132E (pt) * 2000-07-06 2007-01-31 Sankyo Co Sais de adição de ácido derivados de hidropiridina
FR3062850B1 (fr) * 2017-02-10 2020-01-31 Guerbet Procede de preparation monotope de composes organo-iodes
FR3084668A1 (fr) 2018-08-02 2020-02-07 Guerbet Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT330179B (de) * 1972-07-20 1976-06-25 Du Pont Verfahren zur herstellung von neuen 4a-aryl- transdecahydroisochinolinderivaten sowie deren optischen isomeren
US4001248A (en) * 1974-06-07 1977-01-04 Eli Lilly And Company N-cycloalkylmethyl decahydroisoquinolines
US4001247A (en) * 1974-06-07 1977-01-04 Eli Lilly And Company 1-ethyl 3a-(substituted-phenyl) decahydroisoquinoline

Also Published As

Publication number Publication date
BG28417A3 (en) 1980-04-15
SU843743A3 (ru) 1981-06-30
BE860315A (fr) 1978-04-28
FR2369268B1 (US06534493-20030318-C00166.png) 1980-05-16
DK485177A (da) 1978-05-03
AU3023377A (en) 1979-05-10
ZA776498B (en) 1979-06-27
DE2748468A1 (de) 1978-05-03
PL108916B1 (en) 1980-05-31
CA1102319A (en) 1981-06-02
JPS5356683A (en) 1978-05-23
NL7712052A (nl) 1978-05-05
RO72899B (ro) 1981-03-22
PT67195B (en) 1979-03-23
IE45899B1 (en) 1982-12-29
ES463782A1 (es) 1978-12-16
PT67195A (en) 1977-11-01
US4141894A (en) 1979-02-27
GR70052B (US06534493-20030318-C00166.png) 1982-07-26
CA1096861A (en) 1981-03-03
SE7712219L (sv) 1978-05-03
ATA782277A (de) 1980-01-15
GB1585296A (en) 1981-02-25
PL201883A1 (pl) 1979-01-29
DD133797A5 (de) 1979-01-24
IE45899L (en) 1978-05-02
IL53235A0 (en) 1977-12-30
AR221835A1 (es) 1981-03-31
YU257577A (en) 1983-01-21
FR2369268A1 (fr) 1978-05-26
AU510911B2 (en) 1980-07-17
PH13506A (en) 1980-06-03

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Legal Events

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ELJ Ceased due to non-payment of the annual fee