AT337897B - PROCESS FOR PRODUCING NEW ACYLDER DERIVATIVES - Google Patents

PROCESS FOR PRODUCING NEW ACYLDER DERIVATIVES

Info

Publication number
AT337897B
AT337897B AT476975A AT476975A AT337897B AT 337897 B AT337897 B AT 337897B AT 476975 A AT476975 A AT 476975A AT 476975 A AT476975 A AT 476975A AT 337897 B AT337897 B AT 337897B
Authority
AT
Austria
Prior art keywords
acylder
derivatives
producing new
producing
new
Prior art date
Application number
AT476975A
Other languages
German (de)
Other versions
ATA476975A (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ATA476975A publication Critical patent/ATA476975A/en
Application granted granted Critical
Publication of AT337897B publication Critical patent/AT337897B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
AT476975A 1974-06-21 1975-06-20 PROCESS FOR PRODUCING NEW ACYLDER DERIVATIVES AT337897B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH853774A CH609989A5 (en) 1974-06-21 1974-06-21 Process for the preparation of acyl derivatives

Publications (2)

Publication Number Publication Date
ATA476975A ATA476975A (en) 1976-11-15
AT337897B true AT337897B (en) 1977-07-25

Family

ID=4341690

Family Applications (1)

Application Number Title Priority Date Filing Date
AT476975A AT337897B (en) 1974-06-21 1975-06-20 PROCESS FOR PRODUCING NEW ACYLDER DERIVATIVES

Country Status (25)

Country Link
JP (1) JPS625917B2 (en)
AT (1) AT337897B (en)
AU (1) AU498387B2 (en)
BE (1) BE830455A (en)
BR (1) BR7503782A (en)
CA (1) CA1111021A (en)
CH (1) CH609989A5 (en)
CU (1) CU34293A (en)
DD (1) DD121113A5 (en)
DE (1) DE2527291A1 (en)
DK (2) DK153155C (en)
FI (1) FI751815A (en)
FR (1) FR2275215A1 (en)
GB (1) GB1471804A (en)
HU (1) HU170576B (en)
IE (1) IE41888B1 (en)
IL (1) IL47299A (en)
LU (1) LU72771A1 (en)
NL (1) NL180665C (en)
NO (1) NO752202L (en)
NZ (1) NZ177508A (en)
PH (1) PH13030A (en)
SE (1) SE431755B (en)
SU (2) SU635873A3 (en)
ZA (1) ZA753086B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1599232A (en) * 1977-06-03 1981-09-30 Hoffmann La Roche 7-(2-oximinoacetamido)-cephalosporin derivatives
JPS5419990A (en) * 1977-07-14 1979-02-15 Shionogi & Co Ltd Dihydrotriazinylthioxacephalosporin
MC1259A1 (en) * 1978-05-30 1980-01-14 Hoffmann La Roche ACYL DERIVATIVES
FR2474030A1 (en) * 1980-01-17 1981-07-24 Rhone Poulenc Ind 2-Mercapto-1,2,4-triazine, 1,3,4-triazole or tetrazole derivs. - useful as intermediates for antibacterial cephalosporin(s)
FR2494278A1 (en) * 1980-11-20 1982-05-21 Rhone Poulenc Ind NEW DERIVATIVES OF CEPHALOSPORIN, THEIR PREPARATIONS AND THE MEDICINAL PRODUCTS CONTAINING THEM
KR20040014498A (en) * 2001-04-19 2004-02-14 바이오퍼마 무르시아, 에스.에이. Process for preparing cephalosporin derivatives
CA2717753C (en) * 2008-03-05 2016-09-13 Merck Patent Gmbh Pyrazinone derivatives as insulin secretion stimulators, methods for obtaining them and use thereof for the treatment of diabetes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3868369A (en) * 1972-11-14 1975-02-25 Smithkline Corp 3-heterocyclicthiomethylcephalosporins

Also Published As

Publication number Publication date
SU589921A3 (en) 1978-01-25
BE830455A (en) 1975-12-22
DE2527291A1 (en) 1976-01-08
DK153155C (en) 1988-10-31
CA1111021A (en) 1981-10-20
IE41888L (en) 1975-12-21
PH13030A (en) 1979-11-15
AU8191275A (en) 1976-12-09
SU635873A3 (en) 1978-11-30
DK271975A (en) 1975-12-22
SE431755B (en) 1984-02-27
HU170576B (en) 1977-07-28
CU34293A (en) 1979-01-16
DK453687D0 (en) 1987-08-28
JPS625917B2 (en) 1987-02-07
FR2275215A1 (en) 1976-01-16
DK453687A (en) 1987-08-28
JPS5113793A (en) 1976-02-03
FI751815A (en) 1975-12-22
NL7507390A (en) 1975-12-23
GB1471804A (en) 1977-04-27
DK155329B (en) 1989-03-28
DE2527291C2 (en) 1988-01-14
NZ177508A (en) 1978-04-03
AU498387B2 (en) 1979-03-08
NL180665C (en) 1987-04-01
ATA476975A (en) 1976-11-15
SE7506908L (en) 1975-12-22
NO752202L (en) 1975-12-23
IE41888B1 (en) 1980-04-23
DK155329C (en) 1989-08-07
NL180665B (en) 1986-11-03
BR7503782A (en) 1976-07-06
ZA753086B (en) 1976-04-28
LU72771A1 (en) 1977-03-04
DD121113A5 (en) 1976-07-12
IL47299A0 (en) 1976-10-31
DK153155B (en) 1988-06-20
IL47299A (en) 1979-01-31
FR2275215B1 (en) 1980-05-16
CH609989A5 (en) 1979-03-30

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee