AT334373B - Verfahren zur herstellung von neuen 4-hydroxy-3-nitrocarbostyrilderivaten und deren salzen - Google Patents

Verfahren zur herstellung von neuen 4-hydroxy-3-nitrocarbostyrilderivaten und deren salzen

Info

Publication number
AT334373B
AT334373B AT409674A AT409674A AT334373B AT 334373 B AT334373 B AT 334373B AT 409674 A AT409674 A AT 409674A AT 409674 A AT409674 A AT 409674A AT 334373 B AT334373 B AT 334373B
Authority
AT
Austria
Prior art keywords
nitrocarbostyril
hydroxy
derivatives
salts
preparation
Prior art date
Application number
AT409674A
Other languages
German (de)
English (en)
Other versions
ATA409674A (de
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Application granted granted Critical
Publication of AT334373B publication Critical patent/AT334373B/de
Publication of ATA409674A publication Critical patent/ATA409674A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/24Oxygen atoms attached in position 8
    • C07D215/26Alcohols; Ethers thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/10Aza-phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT409674A 1973-05-19 1974-05-17 Verfahren zur herstellung von neuen 4-hydroxy-3-nitrocarbostyrilderivaten und deren salzen AT334373B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2400073A GB1453863A (en) 1973-05-19 1973-05-19 Pharmaceutical compositions comprising nitrocarbostyrils for the treatment of allergic and immunological hypersensitivity
GB2431773 1973-05-22

Publications (2)

Publication Number Publication Date
AT334373B true AT334373B (de) 1976-01-10
ATA409674A ATA409674A (de) 1976-05-15

Family

ID=26256830

Family Applications (1)

Application Number Title Priority Date Filing Date
AT409674A AT334373B (de) 1973-05-19 1974-05-17 Verfahren zur herstellung von neuen 4-hydroxy-3-nitrocarbostyrilderivaten und deren salzen

Country Status (21)

Country Link
JP (1) JPS5030884A (fi)
AR (1) AR201506A1 (fi)
AT (1) AT334373B (fi)
CA (1) CA1030539A (fi)
CH (1) CH601243A5 (fi)
DD (1) DD112126A5 (fi)
DE (1) DE2424076A1 (fi)
DK (1) DK137043B (fi)
ES (1) ES426427A1 (fi)
FI (1) FI153174A (fi)
FR (1) FR2229414B1 (fi)
GB (1) GB1453863A (fi)
HU (1) HU168001B (fi)
IE (1) IE39269B1 (fi)
IL (1) IL44849A (fi)
IN (1) IN139603B (fi)
NL (1) NL7406711A (fi)
PH (1) PH10621A (fi)
SE (1) SE7406631L (fi)
SU (1) SU578869A3 (fi)
ZM (1) ZM7974A1 (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065457A (en) * 1973-05-19 1977-12-27 Beecham Group Limited 4-Hydroxy-3-nitro-carbostyril compounds
US4192876A (en) * 1975-07-23 1980-03-11 Sandoz, Inc. 4-Hydroxy-3-nitro-quinoline-2(1H)-ones
DE2631317A1 (de) * 1975-07-23 1977-02-17 Sandoz Ag Organische verbindungen, ihre verwendung und herstellung
JPS5919095B2 (ja) * 1977-06-22 1984-05-02 大塚製薬株式会社 キノリン誘導体及びその製造法
JPH0681744B2 (ja) * 1986-10-06 1994-10-19 三菱化成株式会社 2,4−ジオキシキノリン誘導体の製造方法
US5622965A (en) * 1993-03-12 1997-04-22 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon 4-hydroxy-3-nitro-1,2-dihydroquinolin-2-ones and the use thereof as excitatory amino acid and glycine receptor antagonists

Also Published As

Publication number Publication date
SU578869A3 (ru) 1977-10-30
ZM7974A1 (en) 1974-12-20
FR2229414A1 (fi) 1974-12-13
JPS5030884A (fi) 1975-03-27
CH601243A5 (fi) 1978-06-30
ES426427A1 (es) 1976-09-16
DD112126A5 (fi) 1975-03-20
IL44849A0 (en) 1974-07-31
IN139603B (fi) 1976-07-10
DE2424076A1 (de) 1974-12-05
NL7406711A (fi) 1974-11-21
GB1453863A (en) 1976-10-27
AR201506A1 (es) 1975-03-21
FR2229414B1 (fi) 1977-11-10
DK137043B (da) 1978-01-09
IE39269B1 (en) 1978-08-30
IE39269L (en) 1974-11-19
DK137043C (fi) 1978-06-05
SE7406631L (fi) 1974-11-20
ATA409674A (de) 1976-05-15
AU6915874A (en) 1975-11-20
CA1030539A (en) 1978-05-02
IL44849A (en) 1978-04-30
HU168001B (fi) 1976-02-28
PH10621A (en) 1977-07-19
FI153174A (fi) 1974-11-20

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee