AT333447B - Verfahren zur herstellung von neuen prostanoesaurederivaten und von deren salzen - Google Patents
Verfahren zur herstellung von neuen prostanoesaurederivaten und von deren salzenInfo
- Publication number
- AT333447B AT333447B AT419172A AT419172A AT333447B AT 333447 B AT333447 B AT 333447B AT 419172 A AT419172 A AT 419172A AT 419172 A AT419172 A AT 419172A AT 333447 B AT333447 B AT 333447B
- Authority
- AT
- Austria
- Prior art keywords
- salts
- production
- acid derivatives
- prostanoic acid
- new
- Prior art date
Links
- WGJJROVFWIXTPA-OALUTQOASA-N prostanoic acid Chemical class CCCCCCCC[C@H]1CCC[C@@H]1CCCCCCC(O)=O WGJJROVFWIXTPA-OALUTQOASA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/535—Organo-phosphoranes
- C07F9/5352—Phosphoranes containing the structure P=C-
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1413971 | 1971-05-11 | ||
| GB3967272A GB1348036A (en) | 1970-05-15 | 1972-01-05 | Transistorized vertical deflection circuit |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA419172A ATA419172A (de) | 1976-03-15 |
| AT333447B true AT333447B (de) | 1976-11-25 |
Family
ID=26235892
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT538973*7A AT328103B (de) | 1971-05-11 | 1972-05-12 | Verfahren zur herstellung von neuen prostanoesaurederivaten |
| AT419172A AT333447B (de) | 1971-05-11 | 1972-05-12 | Verfahren zur herstellung von neuen prostanoesaurederivaten und von deren salzen |
| AT539073*7A AT328104B (de) | 1971-05-11 | 1973-05-12 | Verfahren zur herstellung von neuen prostanoesaurederivaten |
| AT539173*7A AT328105B (de) | 1971-05-11 | 1973-05-12 | Verfahren zur herstellung von neuen prostanoesaurederivaten |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT538973*7A AT328103B (de) | 1971-05-11 | 1972-05-12 | Verfahren zur herstellung von neuen prostanoesaurederivaten |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT539073*7A AT328104B (de) | 1971-05-11 | 1973-05-12 | Verfahren zur herstellung von neuen prostanoesaurederivaten |
| AT539173*7A AT328105B (de) | 1971-05-11 | 1973-05-12 | Verfahren zur herstellung von neuen prostanoesaurederivaten |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS5611699B1 (de) |
| AR (4) | AR194952A1 (de) |
| AT (4) | AT328103B (de) |
| AU (1) | AU462755B2 (de) |
| BE (1) | BE783292A (de) |
| CA (1) | CA1077033A (de) |
| CH (3) | CH590223A5 (de) |
| CS (1) | CS192456B2 (de) |
| DD (1) | DD99155A5 (de) |
| DE (1) | DE2223365C3 (de) |
| DK (1) | DK134598B (de) |
| EG (1) | EG10752A (de) |
| ES (1) | ES402627A1 (de) |
| FI (1) | FI63221C (de) |
| FR (1) | FR2137712A1 (de) |
| HK (1) | HK50176A (de) |
| HU (1) | HU166717B (de) |
| IE (1) | IE37602B1 (de) |
| IL (1) | IL39376A (de) |
| KE (1) | KE2634A (de) |
| NL (1) | NL164272C (de) |
| NO (1) | NO139521C (de) |
| SE (4) | SE399705B (de) |
| SU (1) | SU662007A3 (de) |
| YU (1) | YU35876B (de) |
| ZM (1) | ZM8172A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4304907A (en) * | 1972-05-10 | 1981-12-08 | The Upjohn Company | Bicyclo lactone intermediates for prostaglandin analogs |
| DD118856A5 (de) * | 1972-11-08 | 1976-03-20 | ||
| US3968144A (en) * | 1973-05-21 | 1976-07-06 | The Upjohn Company | 5-Oxa-11-deoxy phenyl- and phenoxy-substituted prostalandin E1 analogs |
| US3966795A (en) * | 1973-05-21 | 1976-06-29 | The Upjohn Company | 5-Oxa-11-deoxyphenyl- and phenoxy-substituted prostaglandin F1.sub.α analogs |
| US4387241A (en) * | 1974-11-01 | 1983-06-07 | American Cyanamid Company | Novel 16-aryloxy-17,18,19,20-tetranorprostanoic acids and derivatives |
| US4149006A (en) * | 1977-01-24 | 1979-04-10 | G. D. Searle & Co. | Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2β side chain |
| US4191774A (en) * | 1978-01-18 | 1980-03-04 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. | Novel 17-aza-PGF2α derivatives and pharmaceutical compositions containing the same |
| US4228296A (en) * | 1979-01-24 | 1980-10-14 | American Cyanamid Company | Novel 16-aryloxy-17,18,19,20-tetranorprostanoic acids and derivatives |
| US4929740A (en) * | 1984-10-09 | 1990-05-29 | Syntex (U.S.A.) Inc. | Process for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives |
| CS264861B1 (en) * | 1986-12-12 | 1989-09-12 | Kral Josef | Agent for cow natality increase |
| CS265947B1 (en) * | 1987-06-16 | 1989-11-14 | Kral Josef | Means for farming animals' ovarian functions control |
| US5565492A (en) * | 1988-07-18 | 1996-10-15 | Alcon Laboratories, Inc. | Prostaglandin combinations in glaucoma therapy |
| CS276003B6 (en) * | 1988-09-28 | 1992-03-18 | Spolana | method of production of (+)-isomer of cloprostenol |
| US5352708A (en) * | 1992-09-21 | 1994-10-04 | Allergan, Inc. | Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| US5688819A (en) * | 1992-09-21 | 1997-11-18 | Allergan | Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| US5510383A (en) * | 1993-08-03 | 1996-04-23 | Alcon Laboratories, Inc. | Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension |
| US6531504B2 (en) * | 2001-05-17 | 2003-03-11 | Allergan, Inc. | Prostanoic acid derivatives as agents for lowering intraocular pressure |
| NZ585517A (en) * | 2007-11-09 | 2012-08-31 | Allergan Inc | 5-[3-(2-Alkyl-cyclopentyl)-propyl]thiophene-2-carboxylic acid derivatives as prostaglandin analogues, and pharmaceutical uses thereof |
-
1972
- 1972-04-27 IE IE557/72A patent/IE37602B1/xx unknown
- 1972-04-28 CA CA140,884A patent/CA1077033A/en not_active Expired
- 1972-05-04 HU HUIE502A patent/HU166717B/hu unknown
- 1972-05-08 AU AU42024/72A patent/AU462755B2/en not_active Expired
- 1972-05-08 ZM ZM81/72*UA patent/ZM8172A1/xx unknown
- 1972-05-08 IL IL39376A patent/IL39376A/xx unknown
- 1972-05-09 NO NO1648/72A patent/NO139521C/no unknown
- 1972-05-09 EG EG193/72A patent/EG10752A/xx active
- 1972-05-09 SE SE7206139A patent/SE399705B/xx unknown
- 1972-05-10 NL NL7206361.A patent/NL164272C/xx not_active IP Right Cessation
- 1972-05-10 SU SU721787999A patent/SU662007A3/ru active
- 1972-05-10 CH CH697472A patent/CH590223A5/xx not_active IP Right Cessation
- 1972-05-10 BE BE783292A patent/BE783292A/xx not_active IP Right Cessation
- 1972-05-10 FI FI1333/72A patent/FI63221C/fi active
- 1972-05-10 ES ES402627A patent/ES402627A1/es not_active Expired
- 1972-05-10 CH CH1566676A patent/CH596165A5/xx not_active IP Right Cessation
- 1972-05-10 FR FR7216685A patent/FR2137712A1/fr active Granted
- 1972-05-10 DK DK236272AA patent/DK134598B/da unknown
- 1972-05-10 CH CH1566776A patent/CH596166A5/xx not_active IP Right Cessation
- 1972-05-11 DD DD162906A patent/DD99155A5/xx unknown
- 1972-05-11 CS CS723161A patent/CS192456B2/cs unknown
- 1972-05-11 YU YU1250/72A patent/YU35876B/xx unknown
- 1972-05-11 JP JP4684472A patent/JPS5611699B1/ja active Pending
- 1972-05-11 AR AR241955A patent/AR194952A1/es active
- 1972-05-12 AT AT538973*7A patent/AT328103B/de not_active IP Right Cessation
- 1972-05-12 AT AT419172A patent/AT333447B/de not_active IP Right Cessation
- 1972-05-12 DE DE2223365A patent/DE2223365C3/de not_active Expired
- 1972-11-30 AR AR245420A patent/AR200484A1/es active
- 1972-11-30 AR AR245418A patent/AR197100A1/es active
- 1972-11-30 AR AR245419A patent/AR197101A1/es active
-
1973
- 1973-05-12 AT AT539073*7A patent/AT328104B/de not_active IP Right Cessation
- 1973-05-12 AT AT539173*7A patent/AT328105B/de not_active IP Right Cessation
-
1975
- 1975-04-15 SE SE7504336A patent/SE7504336L/xx unknown
- 1975-04-15 SE SE7504335A patent/SE7504335L/xx unknown
- 1975-04-15 SE SE7504337A patent/SE7504337L/xx unknown
-
1976
- 1976-05-31 KE KE2634*UA patent/KE2634A/xx unknown
- 1976-08-05 HK HK501/76*UA patent/HK50176A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EIH | Change in the person of patent owner | ||
| ELA | Expired due to lapse of time |